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SNP and Microsatellite Genotyping

SNP and Microsatellite Genotyping
Author: Ali Hajeer
Publisher: Eaton Publishing Company/Biotechniques Books
Total Pages: 0
Release: 2000
Genre: Genetic markers
ISBN: 9781881299387

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Genomics-Assisted Crop Improvement

Genomics-Assisted Crop Improvement
Author: Rajeev K. Varshney
Publisher: Springer Science & Business Media
Total Pages: 517
Release: 2007-12-13
Genre: Technology & Engineering
ISBN: 1402062974

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This superb volume provides a critical assessment of genomics tools and approaches for crop breeding. Volume 1 presents the status and availability of genomic resources and platforms, and also devises strategies and approaches for effectively exploiting genomics research. Volume 2 goes into detail on a number of case studies of several important crop and plant species that summarize both the achievements and limitations of genomics research for crop improvement.


Principles of Population Genetics

Principles of Population Genetics
Author: Daniel L. Hartl
Publisher: Sinauer Associates Incorporated
Total Pages: 652
Release: 2007
Genre: Science
ISBN: 9780878933082

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This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.


Numerical Ecology with R

Numerical Ecology with R
Author: Daniel Borcard
Publisher: Springer
Total Pages: 444
Release: 2018-03-19
Genre: Mathematics
ISBN: 331971404X

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This new edition of Numerical Ecology with R guides readers through an applied exploration of the major methods of multivariate data analysis, as seen through the eyes of three ecologists. It provides a bridge between a textbook of numerical ecology and the implementation of this discipline in the R language. The book begins by examining some exploratory approaches. It proceeds logically with the construction of the key building blocks of most methods, i.e. association measures and matrices, and then submits example data to three families of approaches: clustering, ordination and canonical ordination. The last two chapters make use of these methods to explore important and contemporary issues in ecology: the analysis of spatial structures and of community diversity. The aims of methods thus range from descriptive to explanatory and predictive and encompass a wide variety of approaches that should provide readers with an extensive toolbox that can address a wide palette of questions arising in contemporary multivariate ecological analysis. The second edition of this book features a complete revision to the R code and offers improved procedures and more diverse applications of the major methods. It also highlights important changes in the methods and expands upon topics such as multiple correspondence analysis, principal response curves and co-correspondence analysis. New features include the study of relationships between species traits and the environment, and community diversity analysis. This book is aimed at professional researchers, practitioners, graduate students and teachers in ecology, environmental science and engineering, and in related fields such as oceanography, molecular ecology, agriculture and soil science, who already have a background in general and multivariate statistics and wish to apply this knowledge to their data using the R language, as well as people willing to accompany their disciplinary learning with practical applications. People from other fields (e.g. geology, geography, paleoecology, phylogenetics, anthropology, the social and education sciences, etc.) may also benefit from the materials presented in this book. Users are invited to use this book as a teaching companion at the computer. All the necessary data files, the scripts used in the chapters, as well as extra R functions and packages written by the authors of the book, are available online (URL: http://adn.biol.umontreal.ca/~numericalecology/numecolR/).


Genetic Analysis Workshop 14

Genetic Analysis Workshop 14
Author: Joan E. Bailey-Wilson
Publisher:
Total Pages: 132
Release: 2005
Genre:
ISBN:

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Plant Genotyping II

Plant Genotyping II
Author: Robert J. Henry
Publisher: CABI
Total Pages: 297
Release: 2008
Genre: Science
ISBN: 1845933834

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Describes some of the developments in the field of Plant Genotyping, focusing on single nucleotide polymorphism (SNPs). This book covers the discovery, analysis and uses of SNPs, and examines other approaches to plant genotyping.


Marker-Assisted Plant Breeding: Principles and Practices

Marker-Assisted Plant Breeding: Principles and Practices
Author: B.D. Singh
Publisher: Springer
Total Pages: 542
Release: 2015-06-26
Genre: Science
ISBN: 8132223160

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Marker-assisted plant breeding involves the application of molecular marker techniques and statistical and bioinformatics tools to achieve plant breeding objectives in a cost-effective and time-efficient manner. This book is intended for beginners in the field who have little or no prior exposure to molecular markers and their applications, but who do have a basic knowledge of genetics and plant breeding, and some exposure to molecular biology. An attempt has been made to provide sufficient basic information in an easy-to-follow format, and also to discuss current issues and developments so as to offer comprehensive coverage of the subject matter. The book will also be useful for breeders and research workers, as it offers a broad range of up-to-the-year information, including aspects like the development of different molecular markers and their various applications. In the first chapter, the field of marker-assisted plant breeding is introduced and placed in the proper perspective in relation to plant breeding. The next three chapters describe the various molecular marker systems, while mapping populations and mapping procedures including high-throughput genotyping are discussed in the subsequent five chapters. Four chapters are devoted to various applications of markers, e.g. marker-assisted selection, genomic selection, diversity analysis, finger printing and positional cloning. In closing, the last two chapters provide information on relevant bioinformatics tools and the rapidly evolving field of phenomics.


European Bison

European Bison
Author: Małgorzata Krasińska
Publisher: Springer Science & Business Media
Total Pages: 380
Release: 2013-06-19
Genre: Science
ISBN: 3642365558

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The mighty and majestic European bison is the relictual embodiment of the wildness of prehistoric Europe. Tragically, the millennia since that time have seen so many species driven to extinction by human impacts, and the European bison has only narrowly avoided the same fate. Today, the species represents the symbolic sentinel of successful conservation actions in a world in which such achievements remain few and far between. From an early stage in the restitution of the European bison, husband-and-wife team Małgorzata Krasińska and Zbigniew A. Krasiński have been participating in relevant management initiatives and researching all facets of the bison, from its morphology and diet, to its movements, social life and reproduction, and the conservation management actions that have been taken to save it. Now they have summarised this wealth of knowledge on the species, giving rise to a publication ideal for students, professional biologists and conservationists, but also for all nature enthusiasts. This new edition of the monograph offers extensively updated content taking into account research carried out on the European bison in the last few years. Also featured, a new chapter devoted to knowledge of the genetics of the species drawn up by Małgorzata Tokarska of the Białowieża-based Mammal Research Institute PAS.


Genetics of Bone Biology and Skeletal Disease

Genetics of Bone Biology and Skeletal Disease
Author: Rajesh V. Thakker
Publisher: Academic Press
Total Pages: 878
Release: 2017-10-31
Genre: Medical
ISBN: 0128041986

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Genetics of Bone Biology and Skeletal Disease, Second Edition, is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders. The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models. The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets. Identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluation of treatments Demonstrates how the interactions between bone and joint biology, physiology, and genetics have greatly enhanced the understanding of normal bone function as well as the molecular pathogenesis of metabolic bone disorders Summarizes the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder


Development of a Single Nucleotide Polymorphism (SNP) Assay for Rapid Genotyping of Elk (Cervus Canadensis) Based on Non-invasively Collected Samples

Development of a Single Nucleotide Polymorphism (SNP) Assay for Rapid Genotyping of Elk (Cervus Canadensis) Based on Non-invasively Collected Samples
Author: Gunmeet Kaur Bali
Publisher:
Total Pages:
Release: 2018
Genre:
ISBN: 9780355969221

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In recent decades, non-invasively collected DNA samples have become an essential tool for wildlife genetic monitoring and conservation. While microsatellites have been traditionally used to genotype non-invasive genetic samples, single nucleotide polymorphisms (SNPs) offer several potential advantages over microsatellites. However, high-quantity DNA requirements of most SNP-genotyping platforms have posed a challenge to the use of SNPs for noninvasively collected DNA samples. We used a nanofluidic Integrated Fluidic Circuit (IFC)-based SNP genotyping technology (Fluidigm), which had been used previously on noninvasively collected DNA samples from carnivores. We developed a panel of 96 SNP loci for a Fluidigm platform and validated this assay for genotyping low quantity and quality DNA samples (fecal pellets) obtained from elk (Cervus canadensis). We initially tested 168 SNP loci on 94 high-quality (tissue, blood) samples (29 C. c. nannodes, 33 C. c. roosevelti, and 32 C. c. nelsoni), and selected a final set of 96 highly informative SNP loci based on performance and power to resolve individuals and discriminate subspecies. We then tested this panel of 96 SNPs on serial dilutions of the same high-quality samples (to simulate low quantity and quality DNA) as well as on 40 fecal DNA samples run in duplicate. Call rates were >98% and genotyping error rates