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Smallpox: The Death of a Disease

Smallpox: The Death of a Disease
Author: D. A. Henderson, M.D.
Publisher: Prometheus Books
Total Pages: 338
Release: 2009-09-25
Genre: Science
ISBN: 161592230X

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For more than 3000 years, hundreds of millions of people have died or been left permanently scarred or blind by the relentless, incurable disease called smallpox. In 1967, Dr. D.A. Henderson became director of a worldwide campaign to eliminate this disease from the face of the earth. This spellbinding book is Dr. Henderson’s personal story of how he led the World Health Organization’s campaign to eradicate smallpox—the only disease in history to have been deliberately eliminated. Some have called this feat "the greatest scientific and humanitarian achievement of the past century." In a lively, engrossing narrative, Dr. Henderson makes it clear that the gargantuan international effort involved more than straightforward mass vaccination. He and his staff had to cope with civil wars, floods, impassable roads, and refugees as well as formidable bureaucratic and cultural obstacles, shortages of local health personnel and meager budgets. Countries across the world joined in the effort; the United States and the Soviet Union worked together through the darkest cold war days; and professionals from more than 70 nations served as WHO field staff. On October 26, 1976, the last case of smallpox occurred. The disease that annually had killed two million people or more had been vanquished–and in just over ten years. The story did not end there. Dr. Henderson recounts in vivid detail the continuing struggle over whether to destroy the remaining virus in the two laboratories still that held it. Then came the startling discovery that the Soviet Union had been experimenting with smallpox virus as a biological weapon and producing it in large quantities. The threat of its possible use by a rogue nation or a terrorist has had to be taken seriously and Dr. Henderson has been a central figure in plans for coping with it. New methods for mass smallpox vaccination were so successful that he sought to expand the program of smallpox immunization to include polio, measles, whooping cough, diphtheria, and tetanus vaccines. That program now reaches more than four out of five children in the world and is eradicating poliomyelitis. This unique book is to be treasured—a personal and true story that proves that through cooperation and perseverance the most daunting of obstacles can be overcome.


House on Fire

House on Fire
Author: William H. Foege
Publisher: Univ of California Press
Total Pages: 240
Release: 2011-06-06
Genre: Biography & Autobiography
ISBN: 0520268369

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“Bill Foege takes us inside the world's greatest public health triumph: the eradication of smallpox. It's a story of true determination, passion and courage. The story of smallpox should encourage all of us to continue the critical work of worldwide disease eradication.”--Bill Gates, Co-Chair of the Bill & Melinda Gates Foundation “Bill Foege is one of the public health giants of our times. He was responsible for the design of the campaign that eradicated smallpox—the most important global health achievement in history and possibly the greatest feat in any field of international cooperation. His insights into the nature of this major event will undoubtedly help to meet the global health challenges of the 21st century.”—Julio Frenk, M.D, PhD, Dean, Harvard School of Public Health “The eradication of a disease has long been the holy grail of global health and Bill Foege found it: more than any other person, he was responsible for the eradication of smallpox from the face of the earth. This is a story told by a remarkably humble man, about the extraordinary coalition that he helped to build, and the most impressive global health accomplishment the world has ever seen.”—Mark Rosenberg, author of Real Collaboration: What It Takes for Global Health to Succeed “I am thrilled that Bill Foege, one of the great heroes of the smallpox eradication campaign, has written this important book. It tells a beautiful human story of an incredible public health triumph, and is full of lessons that could be applied to many of the global challenges we face today.”—Helene D. Gayle MD, President and CEO, CARE USA “Bill Foege’s House on Fire is the first-hand account of how a revised strategy to eradicate smallpox was tested, validated, and applied. Without the global adoption of this new surveillance strategy, the final deathblow to this longtime global menace might never have been dealt.”—Adetokunbo O. Lucas, MD, DSc, author of It Was The Best of Times: From Local to Global Health “Smallpox is the most devastating disease the world has known, as it destroyed lives and shaped history over the centuries. House on Fire provides a day-to-day account by my friend Dr. Bill Foege of the battle required to defeat this wily and diabolic virus."--President Jimmy Carter


Assessment of Future Scientific Needs for Live Variola Virus

Assessment of Future Scientific Needs for Live Variola Virus
Author: Committee on the Assessment of Future Scientific Needs for Variola Virus
Publisher: National Academies Press
Total Pages: 126
Release: 1999-05-14
Genre: Medical
ISBN: 030959698X

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In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. In 1986, WHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus, one at the Centers for Disease Control and Prevention and the other at the VECTOR laboratory in Siberia. In June 1999, WHO decided to delay the destruction of these stocks. Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: -- Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies. -- What further benefits, if any, would likely be gained through the use of variola in research and development efforts related to agent detection, diagnosis, prevention, and treatment. -- What unique potential benefits, if any, the study of variola would have in increasing our fundamental understanding of the biology, host-agent interactions, pathogenesis, and immune mechanisms of viral diseases.


Angel of Death

Angel of Death
Author: G. Williams
Publisher: Springer
Total Pages: 453
Release: 2010-05-17
Genre: History
ISBN: 0230293190

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The story of the rise and fall of smallpox, one of the most savage killers in the history of mankind, and the only disease ever to be successfully exterminated (30 years ago next year) by a public health campaign.


The War Against Smallpox

The War Against Smallpox
Author: Michael Bennett
Publisher: Cambridge University Press
Total Pages: 437
Release: 2020-06-18
Genre: History
ISBN: 0521765676

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A history of the global spread of vaccination during the Napoleonic Wars, when millions of children were saved from smallpox.


Smallpox

Smallpox
Author: David Koplow
Publisher: Univ of California Press
Total Pages: 284
Release: 2003-01-21
Genre: Medical
ISBN: 9780520938083

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Though smallpox was eradicated from the planet two decades ago, recent terrorist acts have raised the horrific possibility that rogue states, laboratories, or terrorist groups are in possession of secret stockpiles of the virus that causes the disease, and may be preparing to unleash it on target populations. Because it is a far deadlier killer than other biological warfare agents such as anthrax, and because the universal vaccination against smallpox was halted decades ago, a smallpox attack today would be nothing short of catastrophic. This clear, authoritative study looks at the long and fascinating history of the virus, with an informative overview of the political, biological, environmental, medical, and legal issues surrounding the question of whether or not the virus should be exterminated. The only two known samples of the virus are currently stored in Atlanta and Russia. The World Health Organization has repeatedly scheduled their destruction—an action that would rid the planet of all publicly acknowledged smallpox strains forever. Opponents of this plan argue that by destroying these last samples we are denying the possibility that this unique virus could be turned to beneficial purposes in basic scientific research. Others see the stockpile as part of a deterrent against future germ attacks. Proponents of prompt eradication argue that scientists have already learned all they can from this particular virus, and that by destroying the stockpile we are preventing it from ever falling into the wrong hands. As a thirty-year veteran of arms control issues, David Koplow is uniquely suited to provide readers with an informed and well-considered understanding of the complexities involved in the handling of this deadly virus.


Pox Americana

Pox Americana
Author: Elizabeth A. Fenn
Publisher: Macmillan
Total Pages: 388
Release: 2002-10-02
Genre: History
ISBN: 9780809078219

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A horrifying epidemic of smallpox was sweeping across the Americas when the War of Independence began, and yet little is known about it. Fenn reveals how deeply "variola" affected the outcome of the war in every colony and the lives of everyone in North America. Illustrations.


Albert Einstein

Albert Einstein
Author: Joyce Goldenstern
Publisher: Enslow Publishers, Inc.
Total Pages: 132
Release: 2007-06-01
Genre: Juvenile Nonfiction
ISBN: 9780766028388

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A biography of the life and achievements of Albert Einstein, one of the most important scientists of the twentieth century.


Scourge

Scourge
Author: Jonathan B. Tucker
Publisher: Grove Press
Total Pages: 336
Release: 2002
Genre: History
ISBN: 9780802139399

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A history of one of the world's deadliest diseases traces the influence of the smallpox plague on the course of human civilization, describes Jenner's creation of a vaccine against it and the World Health Organization's global efforts to eradicate it, and examines the dangers it still poses today as


Scientific and Policy Considerations in Developing Smallpox Vaccination Options

Scientific and Policy Considerations in Developing Smallpox Vaccination Options
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 57
Release: 2002-11-28
Genre: Medical
ISBN: 0309086043

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At the World Health Assembly in May 1980, the World Health Organization declared the world free of smallpox. Smallpox vaccination of civilians is now indicated only for laboratory workers directly involved with smallpox or closely related orthopox viruses. However recent questions raised by the terrorist attacks in fall 2001 have renewed concerns about possible outbreaks of smallpox resulting from its use as a biological weapon. In June 2002, the Institute of Medicine convened a public conference to discuss the scientific, clinical, procedural, and administrative aspects of various immunization strategies. Scientific and Policy Considerations in Developing Smallpox Vaccination Options summarizes the presentations and discussions from this workshop.