Skin Decontamination; a Literature Search
Author | : Frances L. Sachs |
Publisher | : |
Total Pages | : 56 |
Release | : 1952 |
Genre | : Nuclear energy |
ISBN | : |
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Author | : Frances L. Sachs |
Publisher | : |
Total Pages | : 56 |
Release | : 1952 |
Genre | : Nuclear energy |
ISBN | : |
Author | : Hanjiang Zhu |
Publisher | : |
Total Pages | : |
Release | : 2020 |
Genre | : Skin |
ISBN | : 9783030240103 |
The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to chemical warfare agents and toxic industrial chemicals because it decreases serious skin damage to the patient and, potentially, their doctor. This multi-authored international text pulls together a century of decontamination research and helps the reader expedite solutions that will decrease morbidity and mortality. Complete with dozens of hiqh quality photographs and illustrations, Skin Decontamination aids industrial hygiene, dermatology, occupational physicians and those involved in the public health arena.
Author | : Hanjiang Zhu |
Publisher | : Springer Nature |
Total Pages | : 280 |
Release | : 2019-09-26 |
Genre | : Medical |
ISBN | : 3030240096 |
The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to chemical warfare agents and toxic industrial chemicals because it decreases serious skin damage to the patient and, potentially, their doctor. This multi-authored international text pulls together a century of decontamination research and helps the reader expedite solutions that will decrease morbidity and mortality. Complete with dozens of hiqh quality photographs and illustrations, Skin Decontamination aids industrial hygiene, dermatology, occupational physicians and those involved in the public health arena.
Author | : Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents |
Publisher | : National Academies Press |
Total Pages | : 303 |
Release | : 1999-02-26 |
Genre | : History |
ISBN | : 0309523141 |
The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.
Author | : United States. Congress. Joint Committee ... |
Publisher | : |
Total Pages | : 2526 |
Release | : 1957 |
Genre | : |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : 24 |
Release | : 1954 |
Genre | : Energy development |
ISBN | : |
Author | : Paul E. Postell |
Publisher | : |
Total Pages | : 64 |
Release | : 1953 |
Genre | : Nuclear energy |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : 18 |
Release | : 2004 |
Genre | : |
ISBN | : |
Battelle's Medical Research and Evaluation Facility (MREF) was tasked to determine the decontaminant effectiveness of Reactive Skin Decontaminant Lotion (RSDL) and to assist U.S. Army Medical Materiel Development Activity (USAMMDA) in requesting a marketing clearance from the U.S. Food and Drug Administration (FDA) as part of the Foreign Comparative Testing (FCT) program and the Joint Services Fixed Site Decontamination System (JSFXD) Program. The task was divided into two phases. Phase I was comprised of a review of open literature and supplemental information provided by USAMMDA. The review included verification of existing decontaminant efficacy data, and identification of the requirements for filing a Premarket Notification Application 510(k) with FDA Center for Devices and Readiological Health (CDRH). Phase II was comprised of four laboratory tasks: three modules and a study to evaluate the offgassing of agent from the applicators following use. Module 1 assessed RSDL performance against VX and HD relative to that of the M291 SDK. Module 2 assessed RSDL's compatibility with fielded materials when decontaminating O-ethyl S-2-(DIISOPROPYLAMINO)ETHYL (VX) and Sulfur Mustard (HD). The third module, labeled Module 8, was comprised of three clinical studies to evaluate RSDL for production of human skin irritation, phototoxicity, and photoallergy. The studies were a 2 1-day cumulative irritation study of RSDL in humans, a repeated insult patch test in humans, and evaluation of phototoxicity and photoallergy. The clinical studies indicated that RSDL exhibits minimal irritation and did not produce phototoxicity or photosensitivity.
Author | : U.S. Atomic Energy Commission |
Publisher | : |
Total Pages | : 82 |
Release | : 1965 |
Genre | : Radioactive decontamination |
ISBN | : |
Author | : Aileen M. Feschuk |
Publisher | : Springer Nature |
Total Pages | : 339 |
Release | : 2022-10-05 |
Genre | : Medical |
ISBN | : 3031092228 |
This book is a comprehensive volume dedicated to dermal absorption and decontamination. Given risks including chemical warfare and accidents with toxic industrial chemicals, studies involving dermal absorption and decontamination are of the utmost importance. Each chapter consists of a systematic review on an important dermal absorption and/or decontamination topic. Chapters address key issues such as the general acceptance of water/ soap and water as the gold standard of dermal decontamination despite the fact that it commonly provides incomplete decontamination and may even result in a “wash-in effect” (an increased penetration of contaminant). Decontamination with other substances (e.g. RSDL) is explored, and factors that affect dermal penetration (e.g. anatomical variation) are summarized. All systematic reviews are comprehensive and up-to-date. Dermal Absorption and Decontamination will be useful for many fields and disciplines. Firstly, information on dermal decontamination may be used by governments for military and national defense purposes in the event of chemical warfare. Additionally, this information would be of use to many production companies, whose employees are at risk of an accident with toxic industrial chemicals. Topics covered in the book will also be of use to pharmaceutical companies, especially those exploring transdermal delivery of drugs and is of great relevance to those in the medical field, particularly dermatologists.