Skeletal Muscle Regeneration in the Mouse
Author | : Michael Kyba |
Publisher | : |
Total Pages | : 346 |
Release | : 2016 |
Genre | : Biomedicine |
ISBN | : 9781493938100 |
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Author | : Michael Kyba |
Publisher | : |
Total Pages | : 346 |
Release | : 2016 |
Genre | : Biomedicine |
ISBN | : 9781493938100 |
Author | : Alexander Mauro |
Publisher | : Raven Press (ID) |
Total Pages | : 582 |
Release | : 1979 |
Genre | : Medical |
ISBN | : |
Author | : Michael Kyba |
Publisher | : Springer |
Total Pages | : 0 |
Release | : 2016-08-06 |
Genre | : Science |
ISBN | : 9781493938087 |
This volume focuses on the cell biology and physiology of skeletal muscle regeneration. This Book is a collection of classic and cutting edge protocols optimized for mice, but in most cases adaptable to rat or other mammalian models, that will allow an investigator to develop and implement a research study on skeletal muscle regeneration. Chapters address the three major areas of study: provoking regeneration by inducing damage to muscle, analyzing the progenitor cells of skeletal muscle, and quantifying overall muscle function. Subjects discussed include: inducing skeletal muscle injury by eccentric contraction; volumetric muscle loss; single myofiber isolation and culture; satellite cell transplantation; muscle clearing for whole mount immunostaining; luciferase tracking of muscle stem cells; mitochondrial and mitophagy flux analysis; in vivo assessment of muscle contractility; force measurements on single isolated myofibers; and analysis of aerobic respiration in intact skeletal muscle tissue by microplate respirometry. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to each respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Skeletal Muscle Regeneration in the Mouse: Methods and Protocols is an essential laboratory reference for research in skeletal muscle growth, damage, repair, degeneration, and regenerative therapy in the mouse model system.
Author | : Alexander Mauro |
Publisher | : Raven Press (ID) |
Total Pages | : 584 |
Release | : 1979 |
Genre | : Fasciae (Anatomy) |
ISBN | : |
Author | : Stefano Schiaffino |
Publisher | : Springer Science & Business Media |
Total Pages | : 385 |
Release | : 2008-01-18 |
Genre | : Medical |
ISBN | : 1402067682 |
Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. It provides up-to-date coverage and presents a broad range of topics.
Author | : Antonio Musarò |
Publisher | : MDPI |
Total Pages | : 500 |
Release | : 2020-11-20 |
Genre | : Science |
ISBN | : 3039434365 |
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration. One of the most ambitious aspirations of modern medical science is the possibility of regenerating any damaged part of the body, including skeletal muscle. This desire has prompted clinicians and researchers to search for innovative technologies aimed at replacing organs and tissues that are compromised. In this context, the papers, collected in this book, addressing a specific aspects of muscle homeostasis and regeneration under physiopathologic conditions, will help us to better understand the underlying mechanisms of muscle healing and will help to design more appropriate therapeutic approaches to improve muscle regeneration and to counteract muscle diseases.
Author | : Sharon Bintliff |
Publisher | : |
Total Pages | : 132 |
Release | : 1960 |
Genre | : Regeneration (Biology) |
ISBN | : |
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Author | : Bruce Spiegelman |
Publisher | : Springer |
Total Pages | : 108 |
Release | : 2018-03-07 |
Genre | : Science |
ISBN | : 3319727907 |
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Author | : Atsushi Asakura |
Publisher | : Springer Nature |
Total Pages | : 472 |
Release | : 2023-03-30 |
Genre | : Science |
ISBN | : 1071630369 |
This volume looks at the latest technologies and methods--combined with new genetic tools available in animal models--used in this constantly evolving field. The chapters in this book are organized into three sections: Section one covers muscle stem cells and progenitor cells; Section Two discusses animal models for muscle stem cells and regeneration; and Section Three explores bioinformatics and imaging analysis for muscle stem cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Skeletal Muscle Stem Cells and Regeneration: Methods and Protocols is a valuable tool for all researchers looking to expand their knowledge on skeletal muscle growth, repair, degeneration, aging, and regenerative medicine.