Single Nucleotide Polymorphism Analysis By Matrix Assisted Laser Desorption Ionization Time Of Flight Mass Spectrometry PDF Download
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Author | : Timothy J. Griffin |
Publisher | : |
Total Pages | : 364 |
Release | : 1999 |
Genre | : |
ISBN | : |
Download Genetic Analysis by Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectrometry Book in PDF, ePub and Kindle
Author | : Alexander R. Ivanov |
Publisher | : Springer Science & Business Media |
Total Pages | : 1081 |
Release | : 2011-06-15 |
Genre | : Science |
ISBN | : 9400708289 |
Download Sample Preparation in Biological Mass Spectrometry Book in PDF, ePub and Kindle
The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the latest inventions and introduction of highly sophisticated mass spectrometry equipment sample preparation becomes an extremely important bottleneck of biomedical analysis. We have a goal of giving the reader several successful examples of sample preparation, development and optimization, leading to the success in analytical steps and proper conclusions made at the end of the day. This book is structured as a compilation of contributed chapters ranging from protocols to research articles and reviews. The main philosophy of this volume is that sample preparation methods have to be optimized and validated for every project, for every sample type and for every downstream analytical technique.
Author | : Robin Liu |
Publisher | : Springer Science & Business Media |
Total Pages | : 216 |
Release | : 2008-12-03 |
Genre | : Medical |
ISBN | : 0387767592 |
Download Integrated Biochips for DNA Analysis Book in PDF, ePub and Kindle
The objective of this book is to provide up-to-date coverage of some of the emerging developments in the field of integrated DNA biochips. It will prove a useful source of information for researchers in the field and for those who are just entering the field of biochip research.
Author | : Zhengdong Fei |
Publisher | : |
Total Pages | : 350 |
Release | : 1999 |
Genre | : |
ISBN | : |
Download Single Nucleotide Polymorphism Analysis by Matrix-assisted Laser Desorption/ Ionization Time-of-flight Mass Spectrometry Book in PDF, ePub and Kindle
Author | : |
Publisher | : Academic Press |
Total Pages | : 200 |
Release | : 2011-03-10 |
Genre | : Science |
ISBN | : 9780123858566 |
Download Advances in Clinical Chemistry Book in PDF, ePub and Kindle
Volume 53 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology. Leading experts from academia and clinical laboratory science Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies
Author | : David E. Bruns |
Publisher | : Amer. Assoc. for Clinical Chemistry |
Total Pages | : 396 |
Release | : 2002 |
Genre | : Medical |
ISBN | : 9781890883607 |
Download Molecular Testing in Laboratory Medicine Book in PDF, ePub and Kindle
Author | : Jose V. Bonilla |
Publisher | : CRC Press |
Total Pages | : 514 |
Release | : 2011-02-23 |
Genre | : Medical |
ISBN | : 1439819939 |
Download Handbook of Analysis of Oligonucleotides and Related Products Book in PDF, ePub and Kindle
Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for applying state-of-the-art analytical techniques in research, development, and manufacturing settings.
Author | : |
Publisher | : |
Total Pages | : 1828 |
Release | : 2000 |
Genre | : Medicine |
ISBN | : |
Download Cumulated Index Medicus Book in PDF, ePub and Kindle
Author | : John Roboz |
Publisher | : CRC Press |
Total Pages | : 577 |
Release | : 2002-03-25 |
Genre | : Medical |
ISBN | : 1420042696 |
Download Mass Spectrometry in Cancer Research Book in PDF, ePub and Kindle
Cancer research is becoming multidisciplinary. The complex structural and therapeutic problems require synergistic approaches employing an assortment of biochemical manipulations, chromatographic or electrophoretic separations, sequencing strategies, and more and more mass spectrometry. Mass Spectrometry in Cancer Research provides a broad
Author | : Yi-Wei Tang |
Publisher | : Springer |
Total Pages | : 541 |
Release | : 2018-11-09 |
Genre | : Medical |
ISBN | : 3319339001 |
Download Advanced Techniques in Diagnostic Microbiology Book in PDF, ePub and Kindle
In recent years, advanced molecular techniques in diagnostic microbiology have been revolutionizing the practice of clinical microbiology in the hospital setting. Molecular diagnostic testing in general and nucleic acid-based amplification methods in particular have been heralded as diagnostic tools for the new millennium. This third edition covers not only the most recent updates and advances, but details newly invented omic techniques, such as next generation sequencing. It is divided into two distinct volumes, with Volume 1 describing the techniques, and Volume 2 addressing their applications in the field. In addition, both volumes focus more so on the clinical relevance of the test results generated by these techniques than previous editions.