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Single Molecule Spectroscopy in Chemistry, Physics and Biology

Single Molecule Spectroscopy in Chemistry, Physics and Biology
Author: Astrid Graslund
Publisher: Springer Science & Business Media
Total Pages: 570
Release: 2010-04-17
Genre: Molecular spectroscopy
ISBN: 3642025986

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Written by the leading experts in the field, this book describes the development and current state of the art in single molecule spectroscopy. The application of this technique, which started 1989, in physics, chemistry and biosciences is displayed.


Single Molecule Spectroscopy

Single Molecule Spectroscopy
Author: R. Rigler
Publisher: Springer Science & Business Media
Total Pages: 375
Release: 2012-12-06
Genre: Science
ISBN: 3642565441

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The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.


Single Molecule Chemistry and Physics

Single Molecule Chemistry and Physics
Author: Chen Wang
Publisher: Springer Science & Business Media
Total Pages: 306
Release: 2006-09-22
Genre: Technology & Engineering
ISBN: 3540395024

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Single-molecule studies constitute a distinguishable category of focused - search in nanoscience and nanotechnology. This book is dedicated to the - troduction of recent advances on single-molecule studies. It will be illustrated that studying single molecules is both intellectually and technologically ch- lenging, and also o?ers vast potential in opening up new scienti?c frontiers. We wish to present the readers with several di?erent techniques for studying single molecules, such as electron-tunneling methods, interaction-force m- surement techniques, optical spectroscopy, plus a number of directions where further progress could be pursued. We hope the work may assist the readers, especially graduate students and those who wish to explore single molecules, to become familiarized with the pace of the progress in this ?eld and the relevant primary techniques. Due to limitation of space, we are not able to elaborate on the technical details of all of the experimental methods that are vital in single molecule studies, so introductions to only selected experimental methods are touched in the context. Since the technical details and theoretical analysis of these techniqueshavealreadybeenthoroughlycoveredinmanyliteratures,weonly provide introductions to the basic principles of the detection techniques here, and focus on their experimental achievements in the area of single-molecule studies. These techniques have proven to be highly e?ective when indep- dently used. The combinationof those techniques could lead to further - vances in the detection capabilities.


Fluorescence Correlation Spectroscopy

Fluorescence Correlation Spectroscopy
Author: R. Rigler
Publisher: Springer Science & Business Media
Total Pages: 503
Release: 2012-12-06
Genre: Science
ISBN: 3642595421

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This is the first book-length treatment of both the theoretical background to fluorescence correlation spectroscopy (FCS) and a variety of applications in various fields of science. The high spatial and temporal resolution of FCS has made it a powerful tool for the analysis of molecular interactions and kinetics, transport properties due to thermal motion, and flow. It contains an essential contribution from Nobel Prize winner M. Eigen, who is credited with inventing FCS.


Single-Molecule Biophysics

Single-Molecule Biophysics
Author: Tamiki Komatsuzaki
Publisher: John Wiley & Sons
Total Pages: 403
Release: 2011-11-16
Genre: Science
ISBN: 111813138X

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Discover the experimental and theoretical developments in optical single-molecule spectroscopy that are changing the ways we think about molecules and atoms The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This latest volume explores the advent of optical single-molecule spectroscopy, and how atomic force microscopy has empowered novel experiments on individual biomolecules, opening up new frontiers in molecular and cell biology and leading to new theoretical approaches and insights. Organized into two parts—one experimental, the other theoretical—this volume explores advances across the field of single-molecule biophysics, presenting new perspectives on the theoretical properties of atoms and molecules. Single-molecule experiments have provided fresh perspectives on questions such as how proteins fold to specific conformations from highly heterogeneous structures, how signal transductions take place on the molecular level, and how proteins behave in membranes and living cells.This volume is designed to further contribute to the rapid development of single-molecule biophysics research. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.


Selective Spectroscopy of Single Molecules

Selective Spectroscopy of Single Molecules
Author: Igor Osad'ko
Publisher: Springer Science & Business Media
Total Pages: 378
Release: 2013-04-17
Genre: Science
ISBN: 3662052482

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This book is the first detailed and comprehensive guide to the theory of optical band shape of guest-molecule-doped crystals, polymers and glasses. Its main focus is on the dynamics of a single molecule, measured with the help of a train of photons emitted at random time moments.


Theory and Evaluation of Single-molecule Signals

Theory and Evaluation of Single-molecule Signals
Author: Eli Barkai
Publisher: World Scientific
Total Pages: 416
Release: 2008
Genre: Science
ISBN: 9812793488

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This book reviews recently developed theoretical and numerical approaches to deal with optical and mechanical signals from individual molecules. The character of data generated by single molecules, and more generally by single nano-objects, qualitatively differs from those obtained in conventional experiments on large ensembles of molecules. Fluctuations, randomness and irreproducibility are central to single-molecule measurements, and the specific methods required to extract reliable and statistically relevant information from them are presented here. With contributions mainly from participants of the ?Theory, Modeling and Evaluation of Single-Molecule Measurements? workshop held in Leiden, the Netherlands, on April 16-20, 2007, this book is an authoritative compendium on the subject.


Single Molecule Detection in Solution

Single Molecule Detection in Solution
Author: Christoph Zander
Publisher: Wiley-VCH
Total Pages: 398
Release: 2002-05-06
Genre: Science
ISBN:

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The detection of single molecules opens up new horizons in analytical chemistry, biology and medicine. This discipline, which belongs to the expanding field of nanoscience, has been rapidly emerging over the last ten years. This handbook provides a thorough overview of the field. It begins with basics of single molecule detection in solution, describes methods and devices (fluorescense correlation spectroscopy, surface enhanced Raman scattering, sensors, especially dyes, screening techniques, especially confocal laser scanning microscopy). In the second part, various applications in life sciences and medicine provide the latest research results. This modern handbook is a highly accessible reference for a broad community from advanced researchers, specialists and company professionals in physics, spectroscopy, biotechnology, analytical chemistry, and medicine. Written by leading authorities in the field, it is timely and fills a gap - up to now there exists no handbook concerning this theme.


Single-Molecule Optical Detection, Imaging and Spectroscopy

Single-Molecule Optical Detection, Imaging and Spectroscopy
Author: W. E. Moerner
Publisher: John Wiley & Sons
Total Pages: 264
Release: 2008-09-26
Genre: Science
ISBN: 3527614702

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Single Molecule Spectroscopy is one of the hottest topics in today's chemistry. It brings us close to the the most exciting vision generations of chemists have been dreaming of: To observe and examine single molecules! While most of chemistry deals with myriads of molecules, this books presents the latest developments for the detection and investigation of single entities. Written by internationally renowned authors, it is a thorough and comprehensive survey of current methods and their applications.


Single Molecules and Nanotechnology

Single Molecules and Nanotechnology
Author: Rudolf Rigler
Publisher: Springer Science & Business Media
Total Pages: 322
Release: 2007-12-07
Genre: Technology & Engineering
ISBN: 3540739246

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This book focuses on recent advances in the rapidly evolving field of single molecule research. These advances are of importance for the investigation of biopolymers and cellular biochemical reactions, and are essential to the development of quantitative biology. Written by leading experts in the field, the articles cover a broad range of topics, including quantum photonics of organic dyes and inorganic nanoparticles and monitoring of single molecule (enzymatic) reactions.