Single Molecule Biophysics And Molecular Biology PDF Download
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Author | : Yuri L. Lyubchenko |
Publisher | : CRC Press |
Total Pages | : 240 |
Release | : 2017-11-22 |
Genre | : Science |
ISBN | : 1351333127 |
Download An Introduction to Single Molecule Biophysics Book in PDF, ePub and Kindle
This book gives an accessible, detailed overview on techniques of single molecule biophysics (SMB), showing how they are applied to numerous biological problems associated with understanding the molecular mechanisms of DNA replication, transcription, and translation, as well as functioning of molecular machines. It covers major single molecule imaging and probing techniques, highlighting key strengths and limitations of each method using recent examples. The chapters begin with a discussion of single molecule fluorescence techniques followed by an overview of the atomic force microscope and its use for direct time-lapse visualization of dynamics of molecular complexes at the nanoscale, as well as applications in measurements of interactions between molecules and mechanical properties of isolated molecules and their complexes. The next chapters address magnetic tweezers and optical tweezers, including instrumentation, fundamentals of operation, and applications. A final chapter turns to nanopore transport and nanopore-based DNA sequencing technology that will play a major role in next-generation genomics and healthcare applications.
Author | : S. Leuba |
Publisher | : |
Total Pages | : 110 |
Release | : 2001 |
Genre | : |
ISBN | : |
Download Single-molecule Biophysics and Molecular Biology Book in PDF, ePub and Kindle
Author | : Peter Hinterdorfer |
Publisher | : Springer Science & Business Media |
Total Pages | : 634 |
Release | : 2009-12-24 |
Genre | : Science |
ISBN | : 0387764976 |
Download Handbook of Single-Molecule Biophysics Book in PDF, ePub and Kindle
This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.
Author | : S.H. Leuba |
Publisher | : Elsevier |
Total Pages | : 263 |
Release | : 2001-12-17 |
Genre | : Science |
ISBN | : 008056061X |
Download Biology at the Single Molecule Level Book in PDF, ePub and Kindle
This is the first book solely devoted to single-molecule biochemistry and molecular biology. Authors were selected on the basis of their contribution to this new and exciting field, and were asked to focus more on the biological problems that can be approached using single-molecule techniques rather than on the techniques per se. It is thought that such techniques will eventually dominate the physical characterization of biologically important macromolecules.
Author | : Tamiki Komatsuzaki |
Publisher | : John Wiley & Sons |
Total Pages | : 403 |
Release | : 2011-11-16 |
Genre | : Science |
ISBN | : 111813138X |
Download Single-Molecule Biophysics Book in PDF, ePub and Kindle
Discover the experimental and theoretical developments in optical single-molecule spectroscopy that are changing the ways we think about molecules and atoms The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This latest volume explores the advent of optical single-molecule spectroscopy, and how atomic force microscopy has empowered novel experiments on individual biomolecules, opening up new frontiers in molecular and cell biology and leading to new theoretical approaches and insights. Organized into two parts—one experimental, the other theoretical—this volume explores advances across the field of single-molecule biophysics, presenting new perspectives on the theoretical properties of atoms and molecules. Single-molecule experiments have provided fresh perspectives on questions such as how proteins fold to specific conformations from highly heterogeneous structures, how signal transductions take place on the molecular level, and how proteins behave in membranes and living cells.This volume is designed to further contribute to the rapid development of single-molecule biophysics research. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.
Author | : S. Leuba |
Publisher | : |
Total Pages | : 140 |
Release | : 2000 |
Genre | : |
ISBN | : |
Download Focussed Issue: Single-molecule Biophysics and Molecular Biology Book in PDF, ePub and Kindle
Author | : Erwin J. G. Peterman |
Publisher | : Humana Press |
Total Pages | : 317 |
Release | : 2011-09-15 |
Genre | : Science |
ISBN | : 9781617792816 |
Download Single Molecule Analysis Book in PDF, ePub and Kindle
Life scientists believe that life is driven, directed, and shaped by biomolecules working on their own or in concert. It is only in the last few decades that technological breakthroughs in sensitive fluorescence microscopy and single-molecule manipulation techniques have made it possible to observe and manipulate single biomolecules and measure their individual properties. The methodologies presented in Single Molecule Techniques: Methods and Protocols are being applied more and more to the study of biologically relevant molecules, such as DNA, DNA-binding proteins, and motor proteins, and are becoming commonplace in molecular biophysics, biochemistry, and molecular and cell biology. The aim of Single Molecule Techniques: Methods and Protocols is to provide a broad overview of single-molecule approaches applied to biomolecules on the basis of clear and concise protocols, including a solid introduction to the most widely used single-molecule techniques, such as optical tweezers, single-molecule fluorescence tools, atomic force microscopy, magnetic tweezers, and tethered particle motion. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Single Molecule Techniques: Methods and Protocols serves as an ideal guide to scientists of all backgrounds and provides a broad and thorough overview of the exciting and still-emerging field of single-molecule biology.
Author | : Mark C. Leake |
Publisher | : Cambridge University Press |
Total Pages | : 291 |
Release | : 2013-01-31 |
Genre | : Science |
ISBN | : 1107005833 |
Download Single-Molecule Cellular Biophysics Book in PDF, ePub and Kindle
Indispensable textbook for undergraduate students in the physical and life sciences, unravelling the inner workings of the cell.
Author | : Mark C. Leake |
Publisher | : Cambridge University Press |
Total Pages | : 291 |
Release | : 2013-01-31 |
Genre | : Science |
ISBN | : 1107005833 |
Download Single-Molecule Cellular Biophysics Book in PDF, ePub and Kindle
Indispensable textbook for undergraduate students in the physical and life sciences, unravelling the inner workings of the cell.
Author | : Andres F. Oberhauser |
Publisher | : Springer Science & Business Media |
Total Pages | : 283 |
Release | : 2012-11-09 |
Genre | : Science |
ISBN | : 1461449219 |
Download Single-molecule Studies of Proteins Book in PDF, ePub and Kindle
In Single Molecule Studies of Proteins, expert researchers discuss the successful application of single-molecule techniques to a wide range of biological events, such as the imaging and mapping of cell surface receptors, the analysis of the unfolding and folding pathways of single proteins, the analysis interaction forces between biomolecules, the study of enzyme catalysis or the visualization of molecular motors in action. The chapters are aimed at established investigators and post-doctoral researchers in the life sciences wanting to pursue research in the various areas in which single-molecule approaches are important; this volume also remains accessible to advanced graduate students seeking similar research goals.