Signal Transduction Research Trends PDF Download
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Author | : Jennifer N. Meyers |
Publisher | : Nova Publishers |
Total Pages | : 270 |
Release | : 2007 |
Genre | : Cell interaction |
ISBN | : 9781600213755 |
Download Trends in Signal Transduction Research Book in PDF, ePub and Kindle
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Author | : Nickolas O. Grachevsky |
Publisher | : Nova Publishers |
Total Pages | : 330 |
Release | : 2007 |
Genre | : Medical |
ISBN | : 9781600214875 |
Download Signal Transduction Research Trends Book in PDF, ePub and Kindle
Signal transduction is any process by which a cell converts one kind of signal or stimulus into another. Processes referred to as signal transduction often involve a sequence of biochemical reactions inside the cell, which are carried out by enzymes and linked through second messengers. In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. Responses of cells to environmental signals, toxins and stressors have profound implications for diverse aspects of human health and disease including development, cystic fibrosis, diabetes, asthma, heart, autoimmune diseases and cancer. The delineation of the signal transduction pathways affected in these and other complex human diseases are likely to present new avenues for therapeutic intervention and understanding of human disease mechanisms.
Author | : Ari Sitaramayya |
Publisher | : Springer |
Total Pages | : 452 |
Release | : 2016-04-01 |
Genre | : |
ISBN | : 9783662501917 |
Download Signal Transduction Book in PDF, ePub and Kindle
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Author | : Ari Sitaramayya |
Publisher | : Springer Science & Business Media |
Total Pages | : 429 |
Release | : 2009-12-02 |
Genre | : Science |
ISBN | : 3642021123 |
Download Signal Transduction: Pathways, Mechanisms and Diseases Book in PDF, ePub and Kindle
Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.
Author | : ljsbrand M. Kramer |
Publisher | : Academic Press |
Total Pages | : 1126 |
Release | : 2015-10-23 |
Genre | : Science |
ISBN | : 0123948193 |
Download Signal Transduction Book in PDF, ePub and Kindle
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions Essential signaling events embedded in rich physiological and pathological contexts Extensive conceptual colour artwork to assist with comprehension of key topics Special emphasis on how molecular structure determines protein function and subcellular localization Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web
Author | : Dave E. Caplin |
Publisher | : Nova Publishers |
Total Pages | : 252 |
Release | : 2006 |
Genre | : Cellular signal transduction |
ISBN | : 9781594546334 |
Download Trends in Cellular Signaling Book in PDF, ePub and Kindle
Cell signalling is the communication inside a cell or with its environment. It plays an important role in cellular growth, survival and apoptosis. For instance, the growth of a cell requires production of certain proteins. The genes that encode these proteins are located in DNA inside the nucleus while the initial signal for cellular growth may come from outside the cell. To induce the expression of these genes, the external signal must pass through specific pathways to reach these genes in DNA. The signalling pathway involves several proteins. If any one of them becomes abnormal or non-functional, the cellular process would be altered, which may cause disease. Therefore, knowing the detailed pathway is very important in understanding the pathogenesis of diseases.
Author | : Toren Finkel |
Publisher | : John Wiley & Sons |
Total Pages | : 490 |
Release | : 2003-07-18 |
Genre | : Science |
ISBN | : 0471448370 |
Download Signal Transduction and Human Disease Book in PDF, ePub and Kindle
This book uniquely relates the broad impact of signal transduction research on the understanding and treatment of human disease. There have been significant advances in the area of signaling in disease processes, yet no resource presently connects these advances with understanding of disease processes and applications for novel therapeutics. Given the emphasis on translational research and biological relevance in biotechnology, and, conversely, the importance of molecular approaches for clinical research, it is evident that a single resource bridging signaling research and human disease will be invaluable.
Author | : Sundas Fayyaz |
Publisher | : Springer |
Total Pages | : 310 |
Release | : 2018-03-07 |
Genre | : Medical |
ISBN | : 3319715534 |
Download Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs Book in PDF, ePub and Kindle
Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics. This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.
Author | : Jonathan W. Boyd |
Publisher | : John Wiley & Sons |
Total Pages | : 336 |
Release | : 2019-04-16 |
Genre | : Science |
ISBN | : 1119060265 |
Download Cellular Signal Transduction in Toxicology and Pharmacology Book in PDF, ePub and Kindle
Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques
Author | : Bruce R. Yanson |
Publisher | : Nova Publishers |
Total Pages | : 282 |
Release | : 2007 |
Genre | : Cell interaction |
ISBN | : 9781600213793 |
Download New Research on Signal Transduction Book in PDF, ePub and Kindle
In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. In such cases the chain of steps is referred to as a "signalling cascade" or a "second messenger pathway" and often results in a small stimulus eliciting a large response. Hormones and other signalling molecules may exit the sending cell by exocytosis or other means of membrane transport. The sending cell is typically of a specialised type. Its recipients may be of one type or several, as in the case of insulin, which triggers diverse and systemic effects. This book sheds new light in this exciting field of cell transportation research.