Sickle Cell Syndromes An Issue Of Hematology Oncology Clinics Of North America E Book PDF Download

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Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book

Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book
Author: Sophie Lanzkron
Publisher: Elsevier Health Sciences
Total Pages: 289
Release: 2022-11-20
Genre: Medical
ISBN: 0323986641

Download Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America, E-Book Book in PDF, ePub and Kindle

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America

Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America
Author: Sophie Lanzkron
Publisher: Elsevier
Total Pages: 0
Release: 2022-12-28
Genre: Medical
ISBN: 9780323986632

Download Sickle Cell Syndromes, An Issue of Hematology/Oncology Clinics of North America Book in PDF, ePub and Kindle

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sophie Lanzkron and Jane Little bring their considerable expertise to the topic of Sickle Cell Syndromes. Top experts in the field cover key topics such as structural racism and impact on sickle cell disease (SCD); pathophysiology and biomarkers of SCD; genetic modifiers of SCD; allogeneic transplant and gene therapy: reproductive health; chronic pain; and more. Contains 16 relevant, practice-oriented topics including innovative therapies, addressing challenging complications, novel science on mechanisms of disease; preventing cognitive decline in people with SCD; quality of life in SCD; and more. Provides in-depth clinical reviews on sickle cell syndromes, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics

Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics
Author: Elliot Vichinsky
Publisher: Elsevier Health Sciences
Total Pages: 281
Release: 2014-04-28
Genre: Medical
ISBN: 0323290000

Download Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics Book in PDF, ePub and Kindle

This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; Regulation of ineffective erythropoiesis in iron metabolism; Altering oxygen affinity; Cellular adhesion and the endothelium; Arginine therapy; Role of the hemostatic system on SCD pathophysiology and potential therapeutics; Adenosine signaling and novel therapies; New approaches to correcting ineffective erythropoiesis and iron dysregulation; New approaches to correcting ineffective erythropoiesis and iron dysregulation; Fetal hemoglobin induction; Gene therapy for hemoglobinopathies; and Oxidative injury and the role of antioxidant therapy.


Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America

Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America
Author: Rachael Grace
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2019-05-05
Genre: Medical
ISBN: 0323673341

Download Pediatric Hematology, An Issue of Hematology/Oncology Clinics of North America Book in PDF, ePub and Kindle

This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.


Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book

Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book
Author: Edward J. BenzJr
Publisher: Elsevier Health Sciences
Total Pages: 241
Release: 2023-03-16
Genre: Medical
ISBN: 044318321X

Download Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book Book in PDF, ePub and Kindle

In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes. Contains 16 practice-oriented topics including molecular basis and genetic modifiers of thalassemia; fetal hemoglobin in thalassemia; clinical complications and their management; iron chelation in thalassemia; fertility and pregnancy in women with transfusion-dependent thalassemia; gene therapy and genome editing in thalassemia; emerging medical therapies for thalassemia; and more. Provides in-depth clinical reviews on thalassemia, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America

Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America
Author: John C. Perkins
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2017-11-06
Genre: Medical
ISBN: 0323611486

Download Hematology/Oncology Emergencies, An Issue of Hematology/Oncology Clinics of North America Book in PDF, ePub and Kindle

This issue of Hematology/Oncology Clinics, edited by Drs. John Perkins and and Jonathan Davis, focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!


An Update on Pediatric Oncology and Hematology , an Issue of Hematology/Oncology Clinics of North America

An Update on Pediatric Oncology and Hematology , an Issue of Hematology/Oncology Clinics of North America
Author: Max J. Coppes
Publisher: Clinics: Internal Medicine
Total Pages: 0
Release: 2010
Genre: Medical
ISBN: 9781437722024

Download An Update on Pediatric Oncology and Hematology , an Issue of Hematology/Oncology Clinics of North America Book in PDF, ePub and Kindle

This issue highlights some of the exciting new developments in pediatric oncology and hematology. Three articles are devoted to pediatric leukemia, which remains the most common form of pediatric cancer. Specifically, articles address ALL, AML, and leukemia in patients with Down syndrome. Other articles that address pediatric oncology include CNS tumors and neuroblastoma as well as advances in cancer immunotherapy. A very interesting article addresses the challenges experienced by adults who survived a childhood cancer. The hematology articles in this issue cover aspects that most clinicians see on a regular basis-sickle cell disease, thalassemia, and hemophilia, and ITP.


Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book

Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book
Author: Daniel E. Bauer
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2017-09-27
Genre: Medical
ISBN: 0323546692

Download Gene Therapy, An Issue of Hematology/Oncology Clinics of North America, E-Book Book in PDF, ePub and Kindle

This issue of Hematology/Oncology Clinics will focus on Gene Therapy. Topics include, but are not limited to Historical Perspective and Current Renaissance, Integrating Vectors, Nonintegrating Vectors, Gene Editing, Conditioning Therapies for Autologous HSCT, Approaches to Immunodeficiency, Approaches to Hemoglobinopathy, Approaches to Hemophilia, Hematopoietic Gene Therapies for Neurologic and Metabolic Disease, Gene Therapy Approaches to HIV and other Infectious Diseases, HSC Approaches to Cancer, and Gene Modified T Cell Therapies for Cancer.


Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book

Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book
Author: Nirali N. Shah
Publisher: Elsevier Health Sciences
Total Pages: 273
Release: 2022-07-19
Genre: Medical
ISBN: 0323987761

Download Gene-Based Therapies for Pediatric Blood Diseases, An Issue of Hematology/Oncology Clinics of North America, E-Book Book in PDF, ePub and Kindle

In this issue of Hematology/Oncology Clinics, guest editors Drs. Sung-Yun Pai and Nirali N. Shah bring their considerable expertise to the topic of Gene-Based Therapies for Pediatric Blood Diseases. Top experts in the field cover key topics such as CAR T-cell therapy: current status; engineered T cells; NK-cell therapy; hemoglobinopathies: beta-thalassemia, sickle cell disease; hemophilia A/B; primary immunodeficiencies; and more. Contains 14 relevant, practice-oriented topics including the evolution of gene therapy; viral vectors in hematopoietic stem cell gene therapy; gene editing in hematopoietic stem cells; nonintegrating vectors and engineered capsids; regulatory aspects of gene therapy; and more. Provides in-depth clinical reviews on gene-based therapies for pediatric blood diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America, E-Book

Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America, E-Book
Author: Jennifer R. Brown︎
Publisher: Elsevier Health Sciences
Total Pages: 217
Release: 2021-07-01
Genre: Medical
ISBN: 0323896936

Download Chronic Lymphocytic Leukemia, An Issue of Hematology/Oncology Clinics of North America, E-Book Book in PDF, ePub and Kindle

This issue of Hematology/Oncology Clinics, guest edited by Dr. Jennifer R. Brown?, will focus on Chronic Lymphocytic Leukemia. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue will include: Chronic Lymphocytic Leukemia: Do We Know the Cell of Origin Yet?; Significance of BCR Stereotypy; Prognostic and Predictive Implications of Cytogenetics and Genomics; Role of Epigenetics in Chronic Lymphocytic Leukemia; Genomics of Resistance to Targeted Therapies; First Line Therapy for Chronic Lymphocytic Leukemia; The Ongoing Unmet Needs in Chronic Lymphocytic Leukemia Therapy; BTK Inhibitors; Minimal Residual Disease; Should Undetectable MRD Be the Goal of Chronic Lymphocytic Leukemia Therapy?; Management of Chronic Lymphocytic Leukemia after Progression on BTK Inhibitors; Role of PI3K Inhibitors in Chronic Lymphocytic Leukemia; Can We Restore the Immunodeficiency of Chronic Lymphocytic Leukemia?; and Immune Therapy for Chronic Lymphocytic Leukemia