Sertoli Cell Biology PDF Download
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| Author | : Michael K. Skinner |
| Publisher | : Elsevier |
| Total Pages | : 511 |
| Release | : 2004-11-23 |
| Genre | : Science |
| ISBN | : 0080492282 |
Download Sertoli Cell Biology Book in PDF, ePub and Kindle
Sertoli cells assist in the production of sperm in the male reproductive system. This book provides a state-of-the-art update on the topic of sertoli cells and male reproduction. It addresses such highly topical areas as stem cells, genomics, and molecular genetics, as well as provides historical information on the discovery of this type of cell, and the pathophysiology of male infertility. * Presents the state-of-the-art research on topics such as stem cell research, transplantation and genomics* Includes contributions from leaders in the field, including several members of the National Academy of Science
| Author | : Michael D. Griswold |
| Publisher | : Academic Press |
| Total Pages | : 488 |
| Release | : 2014-11-19 |
| Genre | : Science |
| ISBN | : 012417048X |
Download Sertoli Cell Biology Book in PDF, ePub and Kindle
Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro. Fully revised Written by experts in the field Summarizes 10 years of research Contains clear explanations and summaries Provides a summary of references over the last 10 years
| Author | : Lonnie Dee Russell |
| Publisher | : |
| Total Pages | : 840 |
| Release | : 1993 |
| Genre | : Sertoli cells |
| ISBN | : |
Download The Sertoli Cell Book in PDF, ePub and Kindle
| Author | : Pedro F. Oliveira |
| Publisher | : Springer |
| Total Pages | : 103 |
| Release | : 2015-11-29 |
| Genre | : Medical |
| ISBN | : 3319197916 |
Download Sertoli Cell Metabolism and Spermatogenesis Book in PDF, ePub and Kindle
This book is focused on Sertoli cell physiology and its role in the spermatogenic event. These cells, known as “nurse cells”, are essential for the normal development of germ cells by offering not only physical support and creating an immune-privileged environment, but also for providing nutritional support. The presence of Sertoli cells promotes the establishment of the appropriate microenvironment so that spermatogenesis may occur. Spermatogenesis maintenance in vivo is highly dependent on the metabolic cooperation established between Sertoli cells and developing germ cells. For many years this metabolic cooperation between testicular cells has been disregarded, but recent advances have highlighted the relevance of these processes for male fertility. Thus, the understanding of the functioning and regulation of these metabolic processes is a crucial step to identify key mechanisms associated with Sertoli cell (dys)function and to enlighten their influence on male fertility.
| Author | : R. Brehm |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 105 |
| Release | : 2005-12-12 |
| Genre | : Medical |
| ISBN | : 3540294465 |
Download Regulation of Sertoli Cell and Germ Cell Differentiation Book in PDF, ePub and Kindle
Unwanted childlessness affects approximately one in six couples worldwide. - though the exact proportion of the predominant cause of the problem remains controversial, according to the World Health Organization (WHO), in nearly 40% of cases the cause can be attributed to the female, in 20% to the male, in 25% to both, and in 15% the cause remains unknown. Based on these ?gures, the - cidence of male factor infertility in the general population is approximately 7%. The majority of these men, approximately 30%, experience irreversible idiopathic infertility and cannot father children without some form of medical intervention. Male factor infertility, in addition, may be caused by testicular germ cell cancer, which is known to represent the most common cancer among young men, aged 15 to 35 years, in Western industrialized countries. The number of affected men has increased dramatically over the past 50 years. There is now growing evidence that human testicular germ cell cancer originates from fetal germ cells exhibiting an aberrant programme of gene expression, and tumour progression may be favoured by an aberrant Sertoli cell-germ cell communication.
| Author | : Cornelia Schulze |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 1984-09-01 |
| Genre | : Medical |
| ISBN | : 9783540136033 |
Download Sertoli Cells and Leydig Cells in Man Book in PDF, ePub and Kindle
The testis is composed of seminiferous tubules and interstitial tissue. The most important component of the interstitial tissue are the testosterone-producing Leydig cells. The seminiferous tubules contain the successive generations of germ cells, which can only exist in the presence of Sertoli cells. Sertoli cells mediate the effect of testosterone, which is indispensable for the maintenance of spermatogenesis. Consequently, the function of the Sertoli cells depends large lyon the function of the Leydig cells, and a local control mechanism between the two cell systems has been assumed. Sertoli cells are supposed to interfere with the regulation of Leydig cell hormone production (Aoki and Fawcett 1978; Sharpe et al. 1981). Few cell types of the testis have received as much attention in recent years as have the Sertoli cells. While comprehensive data had accumulated concerning the differentiation of germ cells, there was formerly little information available on the influence of Sertoli cells on this process. Only through recently developed methods and experimental approaches could their central role in spermatogene sis be verified. Sertoli cells are the only somatic cells in the seminiferous tubules. Their origin is still disputed (for references see Ritzen et al. 1981). They supposedly stem either from the coelomic epithelium or from mesenchymal cells of the genital ridges. According to Wartenberg (1978) they are derived from a gonadal blas tema containing cells from both the coelomic epithelium and the mesonephros.
| Author | : Larry I. Lipshultz |
| Publisher | : Cambridge University Press |
| Total Pages | : 691 |
| Release | : 2009-09-24 |
| Genre | : Medical |
| ISBN | : 1139483242 |
Download Infertility in the Male Book in PDF, ePub and Kindle
The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.
| Author | : Claude Desjardins |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 524 |
| Release | : 1993 |
| Genre | : Medical |
| ISBN | : 9780195062694 |
Download Cell and Molecular Biology of the Testis Book in PDF, ePub and Kindle
This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.
| Author | : Rafal P. Piprek |
| Publisher | : Springer |
| Total Pages | : 444 |
| Release | : 2016-06-14 |
| Genre | : Science |
| ISBN | : 3319319736 |
Download Molecular Mechanisms of Cell Differentiation in Gonad Development Book in PDF, ePub and Kindle
This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions. The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
| Author | : Marco G. Alves |
| Publisher | : Humana |
| Total Pages | : 297 |
| Release | : 2019-06-06 |
| Genre | : Science |
| ISBN | : 9781493985432 |
Download Sertoli Cells Book in PDF, ePub and Kindle
This detailed volume explores the use of Sertoli cells as models in male reproductive biology or as supporters for other cell types, and it answers the need for standardized protocols for their in vitro culture. Prepared for non-specialists as well as experienced researchers that may be interested in a multidisciplinary approach to study these cells, the book examines these remarkable cells that present some unique features that go far beyond the physical and nutritional support of spermatogenesis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Sertoli Cells: Methods and Protocols serves as a valuable resource for experienced researchers in reproductive biology, particularly andrologists, but also for future investigators and young students starting to study these extraordinary cells.
