Serotonin In The Central Nervous System And Periphery PDF Download
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Author | : Akikazu Takada |
Publisher | : Elsevier Science & Technology |
Total Pages | : 280 |
Release | : 1995 |
Genre | : Medical |
ISBN | : |
Download Serotonin in the Central Nervous System and Periphery Book in PDF, ePub and Kindle
This work contains contributions on the progress of serotonin research. On the central nervous system, papers deal with topics such as 5-HT receptors and animal models of anxiety; in the periphery, the roles of 5-HT and effects of antagonists of 5-HT receptors in the circulation are presented.
Author | : Abel Lajtha |
Publisher | : |
Total Pages | : |
Release | : 1982 |
Genre | : Neurochemistry |
ISBN | : |
Download Handbook of Neurochemistry Book in PDF, ePub and Kindle
Author | : Robert Vink |
Publisher | : University of Adelaide Press |
Total Pages | : 354 |
Release | : 2011 |
Genre | : Medical |
ISBN | : 0987073052 |
Download Magnesium in the Central Nervous System Book in PDF, ePub and Kindle
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author | : Giuseppe Di Giovanni |
Publisher | : Springer Science & Business Media |
Total Pages | : 556 |
Release | : 2010-11-30 |
Genre | : Medical |
ISBN | : 1607619415 |
Download 5-HT2C Receptors in the Pathophysiology of CNS Disease Book in PDF, ePub and Kindle
Part of Springer’s “The Receptors,” series, this text is the first ever overview on the research of 5-HT2c receptors. 5-HT2c receptor research has been productive for twenty-five years, but recent years have seen an extraordinary increase in both amount produced and insight gained. 5-HT2c is a prominent central serotonin receptor subtype widely expressed within the central and the peripheral nervous system and is thought to play a key role in the regulation of numerous behaviors. This text covers the molecular, cellular, anatomical, biochemical and behavioral aspects of this receptor, highlighting its distinctive regulatory properties and the emerging functional significance of constitutive activity and RNA-editing in vivo. It also investigates the receptors’ therapeutic potential in many diseases, treated individually in separate chapters, including depression, drug abuse, schizophrenia, eating disorders, Parkinson’s disease, Prader-Willi Syndrome, Alzheimer’s disease and epilepsy.
Author | : Alessia G. Marino |
Publisher | : |
Total Pages | : 0 |
Release | : 2008-10 |
Genre | : Serotonin |
ISBN | : 9781604567649 |
Download Serotonin Book in PDF, ePub and Kindle
Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. In the central nervous system, serotonin is believed to play an important role as a neurotransmitter, in the modulation of anger, aggression, body temperature, mood, sleep, sexuality, and appetite as well as stimulating vomiting. In addition, serotonin is also a peripheral signal mediator. For instance, serotonin is found extensively in the human gastrointestinal tract (about 90%), and the major storage place is platelets in the blood stream. As with all neurotransmitters, the effects of 5-HT on the human mood and state of mind and its role in consciousness are very difficult to ascertain. This new book presents the latest research in the field from around the world. The serotonin (5-HT) system is evolutionarily quite old and is found in all nervous systems. And although making comparative analysis provides ample opportunity for misinterpretation, sufficient similarities exist regarding the 5-HT system and its role in behavioural control to make some generalisations about the function of the 5-HT system and its relationship to specific behaviours and disorders. The 5-HT system is involved in the initiation or the inhibition of many behaviours in a "normal" behavioural repertoire, and many of those are of interest to psychologists. Such behaviours include, but are not limited to mood, aggression, impulsivity, sleep, appetite, and motor function. This book provides leading edge research on this field from around the globe.
Author | : Bryan L. Roth |
Publisher | : Springer Science & Business Media |
Total Pages | : 628 |
Release | : 2008-08-17 |
Genre | : Medical |
ISBN | : 1597450804 |
Download The Serotonin Receptors Book in PDF, ePub and Kindle
A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 448 |
Release | : 1999-09-15 |
Genre | : Technology & Engineering |
ISBN | : 0309172810 |
Download The Role of Protein and Amino Acids in Sustaining and Enhancing Performance Book in PDF, ePub and Kindle
It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Author | : Carla E. M. Hollak |
Publisher | : Oxford University Press |
Total Pages | : 657 |
Release | : 2016 |
Genre | : Medical |
ISBN | : 0199972133 |
Download Inherited Metabolic Disease in Adults Book in PDF, ePub and Kindle
As clinical management of inherited metabolic diseases (IMDs) has improved, more patients affected by these conditions are surviving into adulthood. This trend, coupled with the widespread recognition that IMDs can present differently and for the first time during adulthood, makes the need for a working knowledge of these diseases more important than ever. Inherited Metabolic Disease in Adults offers an authoritative clinical guide to the adult manifestations of these challenging and myriad conditions. These include both the classic pediatric-onset conditions and a number of new diseases that can manifest at any age. It is the first book to give a clear and concise overview of how this group of conditions affects adult patients, a that topic will become a growing imperative for physicians across primary and specialized care.
Author | : |
Publisher | : Academic Press |
Total Pages | : 478 |
Release | : 2019-07-20 |
Genre | : Medical |
ISBN | : 0128173106 |
Download Nutritional Epigenomics Book in PDF, ePub and Kindle
Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. Empowers the reader to employ nutritional epigenomics approaches in their own research Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies
Author | : Fatima Shad Kaneez |
Publisher | : BoD – Books on Demand |
Total Pages | : 318 |
Release | : 2017-07-26 |
Genre | : Medical |
ISBN | : 9535133616 |
Download Serotonin Book in PDF, ePub and Kindle
Serotonin - A Chemical Messenger Between All Types of Living Cells is a very interesting book on the most ancient neurotransmitter, hormone and trophic factor serotonin or 5-hydroxytryptamine (5-HT). This unique chemical is present in all living cells including plants and animals. This book will take us through a serene journey of the evolutionary history of serotonin and its role from man to mollusk. There are many interesting chapters incorporated in this book, including novel approaches for detecting minor metabolites of serotonin in human plasma, production and function of serotonin in cardiac cells, immuno-thrombotic effects of serotonin in platelets to the identification and localization of serotonin in the nervous system and gonad of bivalve mollusks.