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Science of Synthesis: Flow Chemistry in Organic Synthesis

Science of Synthesis: Flow Chemistry in Organic Synthesis
Author: T.F. Jamison
Publisher: Thieme
Total Pages: 932
Release: 2018-12-12
Genre: Science
ISBN: 3132423343

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The aim of this work is to convey the practice, power, and potential of flow chemistry to a larger audience. An emerging and strengthening trend is that flow chemistry is much more than the adaption of batch processes to flow systems. Rather, flow chemistry offers a new paradigm in the way we think about chemical synthesis. This volume demonstrates the enabling power of continuous flow to access new reaction types and different chemistry space and, to this end, it has been compiled by a team of pioneers and leaders, who present both the practical and conceptual aspects of this rapidly growing field. Included are the principles of reactor design, automation, and separations/purifications in flow systems, applications in photochemistry, electrochemistry, gaseous systems, immobilized reagents and catalysts, and multistep processes. The synthesis of peptides, carbohydrates, and pharmaceuticals is covered and several chapters give insight into the use of flow in an industrial context.


Flow Chemistry – Fundamentals

Flow Chemistry – Fundamentals
Author: Ferenc Darvas
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 307
Release: 2014-08-25
Genre: Technology & Engineering
ISBN: 3110388758

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"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.


Micro Reaction Technology in Organic Synthesis

Micro Reaction Technology in Organic Synthesis
Author: Charlotte Wiles
Publisher: CRC Press
Total Pages: 453
Release: 2016-04-19
Genre: Science
ISBN: 143982472X

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While continuous processes have found widespread application within chemical production, members of the research and development communities have historically favored the centuries old technique of iterative batch reactions. With the exception of combinatorial and microwave chemistry, little had been done to change the way that synthetic chemists c


Science of Synthesis

Science of Synthesis
Author: Kurt Faber
Publisher:
Total Pages: 0
Release: 2015
Genre: Biocatalysis
ISBN: 9783132028715

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The three Science of Synthesis volumes on "Biocatalysis in Organic Synthesis" present a broad contemporary overview on the state-of-the-art in enzymatic methods for asymmetric synthesis suitable for academics and industrial researchers working in the field of organic synthesis. The goal is to start a new wave of enthusiasm for biocatalysis in the broader community and to give an overview of the field. "Biocatalysis in Organic Synthesis" offers critical reviews of organic transformations by experts, including experimental procedures. The organization is based on the type of reaction performed under biocatalysis.


Flow Chemistry – Fundamentals

Flow Chemistry – Fundamentals
Author: Ferenc Darvas
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 568
Release: 2021-10-25
Genre: Technology & Engineering
ISBN: 3110693771

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The fully up-dated edition of the two-volume work covers both the theoretical foundation as well as the practical aspects. Presenting the complete insight into driving a chemical reaction provides a deep understanding for new potential technologies. Updated overview on devices and new key concepts of experimental procedures. Vol. 2: Applications.


Principles of Organic Synthesis, 3rd Edition

Principles of Organic Synthesis, 3rd Edition
Author: Richard O.C. Norman
Publisher: CRC Press
Total Pages: 850
Release: 1993-09-16
Genre: Science
ISBN: 9780748761623

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This book is designed for those who have had no more than a brief introduction to organic chemistry and who require a broad understanding of the subject. The book is in two parts. In Part I, reaction mechanism is set in its wider context of the basic principles and concepts that underlie chemical reactions: chemical thermodynamics, structural theory, theories of reaction kinetics, mechanism itself and stereochemistry. In Part II these principles and concepts are applied to the formation of particular types of bonds, groupings, and compounds. The final chapter in Part II describes the planning and detailed execution of the multi-step syntheses of several complex, naturally occurring compounds.


Flow Chemistry – Applications

Flow Chemistry – Applications
Author: Ferenc Darvas
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 350
Release: 2014-11-18
Genre: Technology & Engineering
ISBN: 3110367505

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"Flow Chemistry fills the gap in graduate education by covering chemistry and reaction principles along with current practice, including examples of relevant commercial reaction, separation, automation, and analytical equipment. The Editors of Flow Chemistry are commended for having taken the initiative to bring together experts from the field to provide a comprehensive treatment of fundamental and practical considerations underlying flow chemistry. It promises to become a useful study text and as well as reference for the graduate students and practitioners of flow chemistry." Professor Klavs Jensen Massachusetts Institute of Technology, USA Broader theoretical insight in driving a chemical reaction automatically opens the window towards new technologies particularly to flow chemistry. This emerging concept promotes the transformation of present day's organic processes into a more rapid continuous set of synthesis operations, more compatible with the envisioned sustainable world. These two volumes Fundamentals and Applications provide both the theoretical foundation as well as the practical aspects.


Continuous-Flow Chemistry in the Research Laboratory

Continuous-Flow Chemistry in the Research Laboratory
Author: Toma Glasnov
Publisher: Springer
Total Pages: 119
Release: 2016-06-01
Genre: Science
ISBN: 331932196X

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This book presents a short introduction to the historical background to the field, the state of the art and a brief survey of the available instrumentation and the processing techniques used. The following major areas of interest in synthetic, organic and medicinal chemistry are elaborated on: transition-metal catalyzed reactions, organocatalytic transformations, heterocyclic synthesis, and photochemical reactions. Finally, selected applications in industry are also discussed. With its ample presentation of examples from recent literature, this is an essential and reliable source of information for both experienced researchers and postgraduate newcomers to the field.


Flow Chemistry for the Synthesis of Heterocycles

Flow Chemistry for the Synthesis of Heterocycles
Author: Upendra K. Sharma
Publisher: Springer
Total Pages: 397
Release: 2018-06-20
Genre: Science
ISBN: 3319943286

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This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability. In recent times, flow chemistry has heralded a paradigm shift in organic synthesis as it offers several unique advantages over conventional methods like drastic acceleration of sluggish transformations, enhanced yields, cleaner reactions etc and is gradually gaining a lot of attention among organic chemist worldwide. Given the importance of heterocycles in natural products, medicinal chemistry and pharmaceuticals, this is a well warranted volume and complements the previous volume of Topics in Organometallic Chemistry ‘Organometallic Flow Chemistry’. This volume offers a versatile overview of the topic, besides discussing the recent progress in the flourishing area of flow chemistry in relevance to heterocyclic chemistry; it will also help researchers to better understand the chemistry behind these reactions. This in turn provides a platform for future innovations towards the designing of novel transformations under continuous flow. Thus, this volume will appeal to both the novices in this field as well as to experts in academia and industry.