Role Of Glycogen Synthase Kinase 3 Iin The Regulation Of Vascular Smooth Muscle Cell Glucose Transport And Function PDF Download
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Author | : Robert D. Loberg |
Publisher | : |
Total Pages | : 248 |
Release | : 2003 |
Genre | : |
ISBN | : |
Download Role of Glycogen Synthase Kinase 3 Iin the Regulation of Vascular Smooth Muscle Cell Glucose Transport and Function Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 1876 |
Release | : 2004 |
Genre | : Medicine |
ISBN | : |
Download Index Medicus Book in PDF, ePub and Kindle
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author | : |
Publisher | : |
Total Pages | : 806 |
Release | : 2004 |
Genre | : Dissertations, Academic |
ISBN | : |
Download Dissertation Abstracts International Book in PDF, ePub and Kindle
Author | : |
Publisher | : |
Total Pages | : 1796 |
Release | : 2000 |
Genre | : Medicine |
ISBN | : |
Download Cumulated Index Medicus Book in PDF, ePub and Kindle
Author | : David J. Kwiatkowski |
Publisher | : John Wiley & Sons |
Total Pages | : 415 |
Release | : 2011-08-24 |
Genre | : Science |
ISBN | : 3527644679 |
Download Tuberous Sclerosis Complex Book in PDF, ePub and Kindle
The only comprehensive overview of the molecular basis and clinical features of the genetic disorder tuberous sclerosis, which affects approximately 50,000 people in the US alone. Special focus is placed on novel insights into the signal transduction pathways affected by the disease as well as genotype phenotype correlations, while existing and potential therapies are also discussed in depth. The editors are leading experts in research and treatment of the disease as well as the Vice President of the Tuberous Sclerosis Alliance, the only voluntary health organization for TSC in the US.
Author | : José Marín-García |
Publisher | : Springer Science & Business Media |
Total Pages | : 511 |
Release | : 2011-06-21 |
Genre | : Medical |
ISBN | : 1441994610 |
Download Signaling in the Heart Book in PDF, ePub and Kindle
Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Author | : Robert Vink |
Publisher | : University of Adelaide Press |
Total Pages | : 354 |
Release | : 2011 |
Genre | : Medical |
ISBN | : 0987073052 |
Download Magnesium in the Central Nervous System Book in PDF, ePub and Kindle
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author | : Ronald F. Tuma |
Publisher | : Academic Press |
Total Pages | : 1000 |
Release | : 2011-04-28 |
Genre | : Science |
ISBN | : 9780080569932 |
Download Microcirculation Book in PDF, ePub and Kindle
This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume
Author | : Robert J. Alpern |
Publisher | : Elsevier |
Total Pages | : 2928 |
Release | : 2007-10-10 |
Genre | : Science |
ISBN | : 0080559506 |
Download Seldin and Giebisch's The Kidney Book in PDF, ePub and Kindle
A classic nephrology reference for over 20 years, Seldin & Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch’s The Kidney is your number one source for information. * Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic. * Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics. * Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.
Author | : Michael Johnstone |
Publisher | : Springer Nature |
Total Pages | : 1071 |
Release | : 2023-06-01 |
Genre | : Medical |
ISBN | : 3031131770 |
Download Diabetes and Cardiovascular Disease Book in PDF, ePub and Kindle
This third edition of the book offers an up-to-date review of Diabetes Mellitus with a focus on both Micro- and Macrovascular Disease. The text includes a review of the basic concepts of : Diabetes and Vascular Disease, including Endothelial Dysfunction; The Effect of Insulin on the Vascular System; The Mechanism of Atherosclerosis in Diabetes Mellitus and the Role of Inflammation on the Vascular Tree; and The Role of the Renin-Angiotensin-Aldosteronism on Diabetes Mellitus. Chapters will discuss the Genetics of Type 2 Diabetes Mellitus as well as the Metabolic Syndrome. Other chapters discuss the Risk Factors of Diabetes and Vascular Disease, including Hypertension; Dyslipidemia; and Thrombosis. The book also reviews Microcirculation; Diabetic Nephropathy; Diabetic Retinopathy; as well as the Epidemiology, Diagnosis, and Treatment of Peripheral Vascular Disease; Diabetes and Coronary Artery Disease; Diabetes and Percutaneous Interventions; Diabetes and Cardiac Surgery; and Diabetes and Heart Failure. Chapters conclude with a review of the present-day Treatment of the Diabetic Patient. Diabetes and Cardiovascular Disease, 3rd Edition, offers practicing physicians a cutting-edge scientific and clinical review of diabetic cardiovascular disease, providing both a deeper understanding of its pathology and all the day-to-day practical knowledge needed to treat patients effectively.