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The Role of Glia in Neurotoxicity

The Role of Glia in Neurotoxicity
Author: Michael Aschner
Publisher: CRC Press
Total Pages: 477
Release: 2004-12-28
Genre: Medical
ISBN: 1420039741

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Presenting the latest research in glial cell function gleaned from new techniques in imaging and molecular biology, The Role of Glia in Neurotoxicity, Second Edition covers multiple aspects of glial cells, including morphology, physiology, pharmacology, biochemistry, pathology, and their involvement in the pathophysiology of neurological diseases.


Handbook of Neurochemistry

Handbook of Neurochemistry
Author: Abel Lajtha
Publisher:
Total Pages:
Release: 1982
Genre: Neurochemistry
ISBN:

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Leucine-Rich Repeat Kinase 2 (LRRK2)

Leucine-Rich Repeat Kinase 2 (LRRK2)
Author: Hardy J. Rideout
Publisher: Springer
Total Pages: 280
Release: 2017-03-28
Genre: Medical
ISBN: 3319499696

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This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.


Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies
Author: Jeffrey Noebels
Publisher: OUP USA
Total Pages: 1258
Release: 2012-06-29
Genre: Medical
ISBN: 0199746540

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Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.


Parkinson's Disease and Related Disorders

Parkinson's Disease and Related Disorders
Author: Peter Riederer
Publisher: Springer Science & Business Media
Total Pages: 484
Release: 2006-11-23
Genre: Medical
ISBN: 3211452958

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This book gives a comprehensive overview on current clinical and basic research issues related to Parkinson’s disease and its related disorders. The book is the result of the 16th International Congress of Parkinson’s Disease and Related disorders congress 2005. Its contents are suitable for neurologists, psychiatrists, neurosurgeons, basic researchers, geneticians and patients as well as their relatives.


Interleukin-6-type Cytokines

Interleukin-6-type Cytokines
Author: Andrzej Mackiewicz
Publisher:
Total Pages: 554
Release: 1995
Genre: Medical
ISBN:

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This volume discusses the role of interleukin-6-type cytokines in haematopoietic cell proliferation, neuronal differentiation and acute phase response to inflammation. New data is presented concerning the structure and function of interleukin-6, the leukemia inhibitory factor, interleukin-11, oncostatin M and the ciliary neurotrophic factor. Also discussed is cytokine receptor function, common signal transduction mechanisms, the molecular basis of cytokine-mediated alterations in gene expression, and regulation of cell proliferation. Pre-clinical and clinical studies with these cytokines are evaluated.


Translational Pain Research

Translational Pain Research
Author: Lawrence Kruger
Publisher: CRC Press
Total Pages: 458
Release: 2009-11-24
Genre: Health & Fitness
ISBN: 1439812101

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One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical


Immune and Glial Regulation of Pain

Immune and Glial Regulation of Pain
Author: Joyce A. De Leo
Publisher:
Total Pages: 464
Release: 2007
Genre: Medical
ISBN:

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"Review of immune and glial factors within the peripheral and central nervous systems that relate to chronic pain states. Discussion of novel immune and glial targets for clinical pain control that may yield new analgesic drugs"--Provided by publisher.


Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Total Pages: 388
Release: 2016-04-21
Genre: Medical
ISBN: 1498766579

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Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme