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Hepatocyte and Kupffer Cell Interactions (1992)

Hepatocyte and Kupffer Cell Interactions (1992)
Author: Timothy R. Billiar
Publisher: CRC Press
Total Pages: 339
Release: 2017-11-22
Genre: Science
ISBN: 1351361678

Download Hepatocyte and Kupffer Cell Interactions (1992) Book in PDF, ePub and Kindle

Hepatocyte and Kupffer Cell Interactions presents a comprehensive discussion of historical and recent information regarding this diverse field of research. The role of Kupffer cells and hepatoctyes in normal physiology, nonseptic pathological states, and in sepsis is examined. Microanatomy and methods of experimental study are covered as well. In each of the book's chapters, the role of the Kupffer cell and hepatocyte interaction is placed in context with information on particular liver functions or disease states. Hepatocyte and Kupffer Cell Interactions is an essential reference for leukocyte specialists, gastroenterologists, immunologists, and other researchers working in this fascinating field.


Revival: Hepatocyte and Kupffer Cell Interactions (1992)

Revival: Hepatocyte and Kupffer Cell Interactions (1992)
Author: Timothy R. Billiar
Publisher:
Total Pages:
Release: 2017
Genre: Electronic books
ISBN: 9781351361668

Download Revival: Hepatocyte and Kupffer Cell Interactions (1992) Book in PDF, ePub and Kindle

"Hepatocyte and Kupffer Cell Interactions presents a comprehensive discussion of historical and recent information regarding this diverse field of research. The role of Kupffer cells and hepatoctyes in normal physiology, nonseptic pathological states, and in sepsis is examined. Microanatomy and methods of experimental study are covered as well. In each of the book's chapters, the role of the Kupffer cell and hepatocyte interaction is placed in context with information on particular liver functions or disease states. Hepatocyte and Kupffer Cell Interactions is an essential reference for leukocyte specialists, gastroenterologists, immunologists, and other researchers working in this fascinating field."--Provided by publisher.


Hepatocyte and Kupffer Cell Interactions (1992)

Hepatocyte and Kupffer Cell Interactions (1992)
Author: Timothy R. Billiar
Publisher: CRC Press
Total Pages: 310
Release: 2017-11-22
Genre: Science
ISBN: 1351361686

Download Hepatocyte and Kupffer Cell Interactions (1992) Book in PDF, ePub and Kindle

Hepatocyte and Kupffer Cell Interactions presents a comprehensive discussion of historical and recent information regarding this diverse field of research. The role of Kupffer cells and hepatoctyes in normal physiology, nonseptic pathological states, and in sepsis is examined. Microanatomy and methods of experimental study are covered as well. In each of the book's chapters, the role of the Kupffer cell and hepatocyte interaction is placed in context with information on particular liver functions or disease states. Hepatocyte and Kupffer Cell Interactions is an essential reference for leukocyte specialists, gastroenterologists, immunologists, and other researchers working in this fascinating field.


Cholestatic Liver Disease

Cholestatic Liver Disease
Author: Elizabeth J. Carey
Publisher: Springer
Total Pages: 265
Release: 2014-07-18
Genre: Medical
ISBN: 1493910132

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Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease. Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.


Targeting of Drugs

Targeting of Drugs
Author: Gregory Gregoriadis
Publisher: Springer
Total Pages: 430
Release: 2012-12-12
Genre: Medical
ISBN: 9781468442434

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Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such problems may be resolved by the use of carrier systems that will not only protect the non-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmunology, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.


Liver Anesthesiology and Critical Care Medicine

Liver Anesthesiology and Critical Care Medicine
Author: Gebhard Wagener
Publisher: Springer
Total Pages: 536
Release: 2018-04-11
Genre: Medical
ISBN: 3319642987

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Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.


Alcohol and Cancer

Alcohol and Cancer
Author: Vasilis Vasiliou
Publisher: Springer
Total Pages: 271
Release: 2018-10-26
Genre: Medical
ISBN: 3319987887

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Following the Third Alcohol and Cancer Conference, this volume compiles the most up-to-date research on the role of alcohol consumption in carcinogenesis, from epidemiology to pathology metabolism and stem cells. More specifically, it delves into the effects of alcohol consumption and thyroid cancer, CD133+ progenitor cells, carcinogenic iron accumulation, developmental morphogens, and cancer-inducing epigenetic changes. Alcohol and Cancer: Proceedings of the Third International Conference is a timely update to Biological Basis of Alcohol-Induced Cancer, which followed the Second Alcohol and Cancer Conference, compiling cutting-edge research from graduate students, young scientists, and researchers. It is ideal for graduate students and researchers in oncology, hepatology, epigenetics, and alcohol consumption.


Hepatitis B Virus and Liver Disease

Hepatitis B Virus and Liver Disease
Author: Jia-Horng Kao
Publisher: Springer
Total Pages: 362
Release: 2018-01-12
Genre: Medical
ISBN: 9811048436

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This book provides a comprehensive, state-of-the art review of HBV infection and liver disease. It discusses new data on basic and translational medicine, including the viral life cycle, the immunopathogenesis of virus-induced chronic hepatitis, viral and host genetic factors affecting disease progression, and the mechanism of virus-induced hepatocarcinogenesis, as well as their potential applications in daily clinical practice. The clinical aspects of chronic HBV infection are examined in chapters on the global epidemiology, efficacy of HBV vaccination, natural history, co-infections with HCV, HDV or HIV, and management of special populations including children, pregnant women and patients undergoing immunosuppressive therapy. Further, it describes the advances and perspectives in the development of novel antiviral treatments as possible cures for HBV infection. The book is a valuable resource for medical students, physicians, and researchers who are interested in managem ent of patients with chronic HBV infection and investigation of HBV infection.


The Human Gut-Liver-Axis in Health and Disease

The Human Gut-Liver-Axis in Health and Disease
Author: Aleksander Krag
Publisher: Springer
Total Pages: 294
Release: 2018-11-09
Genre: Medical
ISBN: 3319988905

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The book brings together the current knowledge and future perspectives of the complex physiology and pathophysiology of gut-liver interactions in health and disease. It provides readers with a unique overview and access to knowledge that cannot be obtained elsewhere. The structure is logical and covers all aspect including the normal physiology, changes in various liver diseases, technology, sample collection and various interventions. Thus suitable for general reading, lookup for specific questions or as a reference book within the area. The book allows the reader to access all the knowledge that has been generated within the last 10 years in this field.


Handbook of Pharmacokinetics and Toxicokinetics

Handbook of Pharmacokinetics and Toxicokinetics
Author: Mehdi Boroujerdi
Publisher: CRC Press
Total Pages: 780
Release: 2023-08-22
Genre: Medical
ISBN: 1000878430

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This fully revised and expanded volume is an effort to blend the common approaches to pharmacokinetics and toxicokinetics. It integrates the principles held in common by both fields through a logical and systematic approach, which includes mathematical descriptions of physical and physiological processes employed in the approaches to pharmacokinetics and toxicokinetics modeling. It emphasizes general principles and concepts and related, isolated applications and case study observations. The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research, scientific or regulatory decisions, or for offering advanced courses/workshops and seminars. Features: Comprehensive handbook on principles and applications of PK/TK appealing to a diverse audience including scientists and students An excellent text fully revised and fully updated for anyone interested in the theoretical and practical pharmacokinetics The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research Incorporates research relevant to SDGs and of interest to industrial and regulatory environmental scientists involved in chemical contamination research and regulatory decision making related to soil, water, and ocean Includes sections on applications and case studies