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Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology

Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology
Author: Seth Kwabena Amponsah
Publisher: Springer Nature
Total Pages: 384
Release: 2022-10-25
Genre: Medical
ISBN: 3031123980

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This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges


Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology

Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology
Author: Irving Sunshine
Publisher: CRC Press
Total Pages: 807
Release: 2023-06-14
Genre: Medical
ISBN: 1000943038

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Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr


Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology

Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology
Author: Irving Sunshine
Publisher:
Total Pages: 0
Release: 2008
Genre: MEDICAL
ISBN: 9781003418153

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Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr


Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology

Recent Developments in Therapeutic Drug Monitoring and Clinical Toxicology
Author: Irving Sunshine
Publisher:
Total Pages: 0
Release: 2008
Genre: MEDICAL
ISBN: 9781000949674

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Papers from the Second International Conference on TDM Toxicology (date and place not stated) describe research on various aspects of therapeutic monitoring pharmacology, selected high-performance liquid chromatographic methods, antiepileptics, substances subject to abuse, inorganics. Over 100 contr


Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography
Author: Steven H.Y. Wong
Publisher: Routledge
Total Pages: 521
Release: 2017-09-19
Genre: Medical
ISBN: 135140847X

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This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses.Written by authoritative contributors who bring many years of personal laboratory/clinical experience to the book, this interdisciplinary work : presents the principlesof TDM, sampling techniques, and various instrumentation topics, including computerinterfacing, mass spectrometry, fluorescence , electrochemical detection, and bloodcollection devices . .. examines six primary classes of drugs, complete with recommendedLC procedures and emphasizing recently introduced drugs and their LC analyses. .. and documents medicolegal guidelines and laboratory management considerations,providing a contemporary assessment of today's laboratory needs.The only practical, current guide available on the subject, Therapeutic Drug Monitoringand Toxicology by Li([uid Chromatography belongs in the personal libraries of clinicaland analytical chemists and biochemists, clinical pharmacologists, clinical toxicologists,clinical pathologists, immunologists, liquid chromatographers, mass spectroscopists, laboratorydirectors, laboratory instrument manufacturers , and medical technologists. Thebook is also vital supplementary reading for advanced undergraduate and graduate-levelclinical chemistry, toxicology, clinical pathology, and liquid chromatography course.


Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)

Handbook of Analytical Therapeutic Drug Monitoring and Toxicology (1996)
Author: Steven H.Y. Wong
Publisher: CRC Press
Total Pages: 367
Release: 2017-11-22
Genre: Medical
ISBN: 1351364286

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Adapting modern advances in analytical techniques to daily laboratory practices challenges many toxicologists, clinical laboratories, and pharmaceutical scientists. The Handbook of Analytical Therapeutic Drug Monitoring and Toxicology helps you keep abreast of the innovative changes that can make your laboratory - and the studies undertaken in it - a success. This volume simplifies your search for appropriate techniques, describes recent contributions from leading investigators, and provides valuable evaluations and advice.


Advances in Chromatographic Techniques for Therapeutic Drug Monitoring

Advances in Chromatographic Techniques for Therapeutic Drug Monitoring
Author: Amitava Dasgupta
Publisher: CRC Press
Total Pages: 475
Release: 2009-10-06
Genre: Medical
ISBN: 1420067591

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For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for imp