Recent Advances In Measuring And Controlling Synaptic Communication PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Recent Advances In Measuring And Controlling Synaptic Communication PDF full book. Access full book title Recent Advances In Measuring And Controlling Synaptic Communication.
| Author | : Jacopo Lamanna |
| Publisher | : Frontiers Media SA |
| Total Pages | : 117 |
| Release | : 2023-11-10 |
| Genre | : Science |
| ISBN | : 2832536379 |
Download Recent Advances in Measuring and Controlling Synaptic Communication Book in PDF, ePub and Kindle
Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.
| Author | : Jeffrey Noebels |
| Publisher | : OUP USA |
| Total Pages | : 1258 |
| Release | : 2012-06-29 |
| Genre | : Medical |
| ISBN | : 0199746540 |
Download Jasper's Basic Mechanisms of the Epilepsies Book in PDF, ePub and Kindle
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 610 |
| Release | : 2000-11-13 |
| Genre | : Social Science |
| ISBN | : 0309069882 |
Download From Neurons to Neighborhoods Book in PDF, ePub and Kindle
How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
| Author | : Wulfram Gerstner |
| Publisher | : Cambridge University Press |
| Total Pages | : 591 |
| Release | : 2014-07-24 |
| Genre | : Computers |
| ISBN | : 1107060834 |
Download Neuronal Dynamics Book in PDF, ePub and Kindle
This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.
| Author | : Scott Brady |
| Publisher | : Academic Press |
| Total Pages | : 1120 |
| Release | : 2011-11-02 |
| Genre | : Science |
| ISBN | : 0080959016 |
Download Basic Neurochemistry Book in PDF, ePub and Kindle
Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at http://elsevierdirect.com/companions/9780123749475
| Author | : Jian-Sheng Lin |
| Publisher | : Frontiers Media SA |
| Total Pages | : 100 |
| Release | : 2015-03-18 |
| Genre | : Brain |
| ISBN | : 2889194345 |
Download Histamine in the brain Book in PDF, ePub and Kindle
Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regulation, in a region-specific manner, of other neurotransmitter systems. Neurochemical preclinical studies have clearly shown that histamine interacts and modulates the release of neurotransmitters that are recognized as major modulators of cognitive processing and motivated behaviours. As a consequence, the histamine system has been proposed as a therapeutic target to treat sleep-wake disorders and cognitive dysfunctions that accompany neurodegenerative and neuroinflammatory pathologies. Last decades have witnessed an unexpected explosion of interest in brain histamine system, as new receptors have been discovered and selective ligands synthesised. Nevertheless, the complete picture of the histamine systems fine-tuning and its orchestration with other pathways remains rather elusive. This Research Topic is intended to offer an inter-disciplinary forum that will improve our current understanding of the role of brain histamine and provide the fundamentals necessary to drive innovation in clinical practice and to improve the management and treatment of neurological disorders.
| Author | : Li Yang |
| Publisher | : Frontiers Media SA |
| Total Pages | : 128 |
| Release | : 2022-06-16 |
| Genre | : Science |
| ISBN | : 2889763862 |
Download Current Advances in Neurodevelopmental Disorders: Piecing Together the Candidate Path That Guides the Translation From Etiology to Treatment Book in PDF, ePub and Kindle
| Author | : George J. Siegel |
| Publisher | : Lippincott Raven |
| Total Pages | : 1216 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : |
Download Basic Neurochemistry Book in PDF, ePub and Kindle
Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 993 |
| Release | : 2013-05-06 |
| Genre | : Science |
| ISBN | : 0123973481 |
Download Patterning and Cell Type Specification in the Developing CNS and PNS Book in PDF, ePub and Kindle
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
| Author | : Thomas C. Südhof |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 582 |
| Release | : 2007-12-07 |
| Genre | : Medical |
| ISBN | : 3540748059 |
Download Pharmacology of Neurotransmitter Release Book in PDF, ePub and Kindle
It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.
