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Not everybody can find a meaning for life in the middle of a moment of unimaginable pain. But Roseli Tardelli did. In the death of her HIV-infected brother, Sérgio, she found a cause worth fighting for. But a glance at Agência AIDS suffices to see all the work that has been done to bring more rights of the HIV-infected and promote information about AIDS to the population. The path is tortuous, the hurdles are enormous and countless, but Roseli and her team of collaborators manage to channel such powerful energy that barriers are crossed nearly every day. With this publication, Senac São Paulo presents more than a story about a fight, it also brings up relevant discussions and information – through the glossary and the timeline – for the reader to reflect upon the journey of the disease in Brazil and in the world and, at the same time, it pays tribute to the people who fight for a more humane treatment of those infected with HIV.