Quantitative Methods In Pharmaceutical Research And Development PDF Download
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Author | : Olga V. Marchenko |
Publisher | : Springer Nature |
Total Pages | : 445 |
Release | : 2020-09-24 |
Genre | : Medical |
ISBN | : 3030485552 |
Download Quantitative Methods in Pharmaceutical Research and Development Book in PDF, ePub and Kindle
This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.
Author | : S. W. Bergman |
Publisher | : CRC Press |
Total Pages | : 272 |
Release | : 2020-09-30 |
Genre | : |
ISBN | : 9780367451660 |
Download Statistical Methods for Pharmaceutical Research Planning Book in PDF, ePub and Kindle
This book focuses on statistical methods which impinge more or less directly on the decisions that are made during the course of pharmaceutical and agro-chemical research, considering the four decision-making areas.
Author | : Themistocles P. Hadjiioannou |
Publisher | : Wiley-VCH |
Total Pages | : 461 |
Release | : 1993-03-30 |
Genre | : Science |
ISBN | : 9780471188988 |
Download Quantitative Calculations in Pharmaceutical Practice and Research Book in PDF, ePub and Kindle
Quantitative calculations are common everyday practice for the analytical chemist in his laboratory work. This book aims at familiarizing students and technicians with such calculations done in pharmaceutical analysis, biopharmaceutics, pharmacokinetics, pharmacy practice, pharmaceutical chemistry, physical pharmacy and radiopharmacy. It exposes the reader to various approaches for problem solving and aids in consolidating theoretical knowledge by applying it to the solution of real problems. Structured in 15 chapters, each one containing a short introduction of the relevant theory and equations to facilitate the comprehension of theoretical principles and the solution of the relevant problems.
Author | : Per Winkel |
Publisher | : John Wiley & Sons |
Total Pages | : 280 |
Release | : 2007-06-13 |
Genre | : Mathematics |
ISBN | : 9780470515891 |
Download Statistical Development of Quality in Medicine Book in PDF, ePub and Kindle
The promotion of standards and guidelines to advance quality assurance and control is an integral part of the health care sector. Quantitative methods are needed to monitor, control and improve the quality of medical processes. Statistical Development of Quality in Medicine presents the statistical concepts behind the application of industrial quality control methods. Filled with numerous case studies and worked examples, the text enables the reader to choose the relevant control chart, to critically apply it, improve it if necessary, and monitor its stability. Furthermore, the reader is provided with the necessary background to critically assess the literature on the application of control charts and risk adjustment and to apply the findings. Contains a user-friendly introduction, setting out the necessary statistical concepts used in the field. Uses numerous real-life case studies from the literature and the authors’ own research as the backbone of the text. Provides a supplementary website featuring problems and answers drawn from the book, alongside examples in Statgraphics. The accessible style of Statistical Development of in Clinical Medicine invites a large readership. It is primarily aimed at health care officials, and personnel responsible for developing and controlling the quality of health care services. However, it is also ideal for statisticians working with health care problems, diagnostic and pharmaceutical companies, and graduate students of quality control.
Author | : David J. Livingstone |
Publisher | : Royal Society of Chemistry |
Total Pages | : 517 |
Release | : 2012 |
Genre | : Medical |
ISBN | : 1849731667 |
Download Drug Design Strategies Book in PDF, ePub and Kindle
This book brings together drug design practitioners, all leaders in their field, who are actively advancing the field of quantitative methods to guide drug discovery, from structure-based design to empirical statistical models - from rule-based approaches to toxicology to the fields of bioinformatics and systems biology. The aim of the book is to show how various facets of the drug discovery process can be addressed in a quantitative fashion (ie: numerical analysis to enable robust predictions to be made). Each chapter includes a brief review of the topic showing the historical development of.
Author | : Yuzhen Luo |
Publisher | : |
Total Pages | : |
Release | : 2016 |
Genre | : Technology |
ISBN | : |
Download Quantitative Methods in System-Based Drug Discovery Book in PDF, ePub and Kindle
Modern pharmaceutical industries have faced significant challenges to deliver safe and effective medicines because of significant toxicity and severe side effects of discovered drugs. On the other hand, recent developments and advances in system-based pharmacology aim to address these challenges. In this chapter, we provide an overview of quantitative methods for system-based drug discovery. System-based drug discovery integrates chemical, molecular, and systematic information and applies this knowledge to the designing of small molecules with controlled toxicity and minimized side effects. First, we discuss current approaches for drug discovery and outline their advantages and disadvantages. Next, we introduce basic concepts of systems pharmacology with an emphasis on ligand-based drug discovery and target identification. This is followed by a discussion on structure-based drug design and statistical tools for pharmaceutical research. Finally, we provide an overview of future directions in systems pharmacology that will guide further developments.
Author | : David S. Zuckerman |
Publisher | : Routledge |
Total Pages | : 146 |
Release | : 2017-05-15 |
Genre | : Business & Economics |
ISBN | : 1351911538 |
Download Pharmaceutical Metrics Book in PDF, ePub and Kindle
'What gets measured gets fixed' and this is as true of the pharmaceutical industry as any other. The problem is that pharmaceutical businesses are complex. Drug research and development involves extended and expensive processes; defining appropriate metrics for these processes is not easy, yet ineffective or misguided metrics can be more damaging than none at all. David Zuckerman's Pharmaceutical Metrics is an extremely practical guide to selecting a system, selling it to top management, choosing and defining the right metrics for your system, communicating and displaying the results. And because metrics are about how to shape and develop your business, he explores how to deploy them organization-wide and make sure that they are driving business improvement. In order to reflect the needs of different types of pharmaceutical company the author uses four sample companies, throughout the book, to illustrate the principles for 'big pharma', 'micro pharma', a virtual development company and a CRO. This highly practical book provides a step-by-step guide to creating a state-of-the-art, strategy-driven metrics system for pharmaceutical R&D, supported by case studies of the techniques applied and tips for optimizing the system.
Author | : Zubin Austin |
Publisher | : Elsevier Health Sciences |
Total Pages | : 280 |
Release | : 2018-02-21 |
Genre | : Medical |
ISBN | : 070207425X |
Download Research Methods in Pharmacy Practice Book in PDF, ePub and Kindle
This is a comprehensive guide to applying research methods to practice problems. It uses case-based examples and activities rooted in practice to support development of knowledge, skills, and confidence in applying evidence-based research methods. An array of different methodologies and qualitative/quantitative methods are described. Examples of topics include distinction between methodologies and methods, ethics protocols, as well as design/implementation/data analysis/interpretation of findings using methods such as surveys, interviews, focus groups, observational research, database mining, text and document analysis, quality improvement (PDSA cycles), economic (cost/benefit) evaluations. Perfect for MPharm students doing their research thesis, but relevant to all bioscience students undertaking research projects. Use of pharmacy practice case examples (in community, hospital, ambulatory, primary care and other settings) throughout. Examples of how to tackle a research question from different perspectives, e.g. which is the best way to answer each question and why. Inter-professional practice and research emphasized. Self-assessment and self-reflection questions to help readers confirm their understanding/learning. A one-stop research-method teaching resource for faculty.
Author | : Qi Jiang |
Publisher | : CRC Press |
Total Pages | : 374 |
Release | : 2014-12-08 |
Genre | : Mathematics |
ISBN | : 1466555475 |
Download Quantitative Evaluation of Safety in Drug Development Book in PDF, ePub and Kindle
State-of-the-Art Methods for Drug Safety AssessmentResponding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product deve
Author | : N. Anthony Armstrong |
Publisher | : CRC Press |
Total Pages | : 294 |
Release | : 2002-09-11 |
Genre | : Medical |
ISBN | : 9780203483091 |
Download Pharmaceutical Experimental Design And Interpretation Book in PDF, ePub and Kindle
This work provides a description of the principles of experimental design and their application to pharmaceutical research. It includes worked examples taken from a wide variety of pharmaceutical techniques and processes.