Proteins At Liquid Interfaces PDF Download
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Author | : D. Möbius |
Publisher | : Elsevier |
Total Pages | : 509 |
Release | : 1998-04-24 |
Genre | : Science |
ISBN | : 0080540007 |
Download Proteins at Liquid Interfaces Book in PDF, ePub and Kindle
The interfacial behaviour of surfactants and proteins, and their mixtures, is of importance in a wide range of areas such as food technology, detergency, cosmetics, coating processes, biomedicine, pharmacy and biotechnology. Methods such as surface and interfacial tension measurements and interfacial dilation and shear rheology characterise the relationships between these interfacial properties and the complex behaviour of foams and emulsions is established. Recently-developed experimental techniques, such as FRAP which enable the measurement of molecular mobility in adsorption layers, are covered in this volume. The development of theories to describe the thermodynamic surface state or the exchange of matter for proteins and protein/surfactant mixtures is also described. Features of this book: • Reflects the state-of-the-art research and application of protein interfacial layers rather than a snapshot of only some recent developments. • Emphasis is placed on experimental details as well as recent theoretical developments. • New experimental techniques applied to protein interfacial layers are described, such as FRAP or ADSA, or rheological methods to determine the mechanical behaviour of protein-modified interfaces. • A large number of practical applications, ranging from emulsions relevant in food technology for medical problems such as lung surfactants, to the characterisation of foams intrinsic to beer and champagne production. The book will be of interest to research and university institutes dedicated to interfacial studies in chemistry, biology, pharmacy, medicine and food engineering. Industrial departments for research and technology in food industry, pharmacy, medicine and brewery research will also find this volume of value.
Author | : Philippe Déjardin |
Publisher | : Springer Science & Business Media |
Total Pages | : 341 |
Release | : 2006-09-28 |
Genre | : Science |
ISBN | : 3540326588 |
Download Proteins at Solid-Liquid Interfaces Book in PDF, ePub and Kindle
This book opens with a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. Presented here are methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS). Also described are sensitive bench techniques for measuring the orientation and structure of proteins at solid-liquid interfaces, including total internal reflection ellipsometry (TIRE), dual polarisation interferometry (DPI) and time of flight - secondary ion mass spectrometry (TOF–SIMS). A model study of fibronectin at polymer surfaces is included, as are studies using microporous membranes and textiles with immobilized enzymes for large-scale applications. Biocompatibility, anti-fouling properties and surface modification to modulate the adsorption and activity of biomolecules are among the other topics addressed in this invaluable book.
Author | : Ananthakrishnan G. Sethuraman |
Publisher | : |
Total Pages | : 210 |
Release | : 2004 |
Genre | : |
ISBN | : |
Download Proteins at Solid-liquid Interfaces Book in PDF, ePub and Kindle
Author | : Jinjiang Li |
Publisher | : Springer Nature |
Total Pages | : 338 |
Release | : 2021-02-12 |
Genre | : Medical |
ISBN | : 3030571777 |
Download Protein Instability at Interfaces During Drug Product Development Book in PDF, ePub and Kindle
Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and form aggregates, resulting in loss of efficacy and potential immunogenicity. This book covers both the fundamental aspects of proteins at interfaces and the quantification of interfacial behaviors of proteins. Importantly, this book introduces the industrial aspects of protein instabilities at interfaces, including the processes that introduce new interfaces, evaluation of interfacial instabilities, and mitigation strategies. The audience that this book targets encompasses scientists in the pharmaceutical and biotech industry, as well as faculty and students from academia in the surface science, pharmaceutical, and medicinal chemistry areas.
Author | : Adam Till Garland |
Publisher | : |
Total Pages | : 230 |
Release | : 2014 |
Genre | : |
ISBN | : |
Download The Behavior of Proteins at Solid-liquid Interfaces Book in PDF, ePub and Kindle
The behavior of a protein molecule at the solid-liquid interface is a worthy scientific problem for at least three reasons. The main driving force for studying this problem is a practical one, as many areas of bio-related technologies, such as medical implants, biosensing, and drug delivery, require the understanding of protein-surface interactions. In this dissertation, the nature of the precursive weakly adsorbed state of proteins during binding is reviewed. From this perspective, the adsorption and binding of proteins to a solid block copolymer thin film was achieved with regular spacing. Further efforts produced a monolayer of green fluorescent protein (GFP) covalently bound with regular spacing and orientation to a diblock copolymer thin film. This protein could be folded and refolded by changing solvent characteristics. We also explored the binding of DC-SIGN to mannose and mannotriose bearing lipid membranes. While no binding was observed, the usefulness of the lipid-based glycan microarray was proven using the well-studied CTB-GM1 binding motif.
Author | : |
Publisher | : |
Total Pages | : 561 |
Release | : 1995 |
Genre | : |
ISBN | : |
Download Proteins at Interfaces II Book in PDF, ePub and Kindle
Author | : P. Kralchevsky |
Publisher | : |
Total Pages | : 680 |
Release | : 2001-01-22 |
Genre | : Medical |
ISBN | : |
Download Particles at Fluid Interfaces and Membranes Book in PDF, ePub and Kindle
Planar fluid interfaces -- Interfaces of moderate curvature : theory of capillarity -- Surface bending moment and curvature elastic moduli -- General curved interfaces and biomembranes -- Liquid films and interactions between particle and surface -- Particles at interfaces : deformations and hydrodynamic interactions -- Lateral capillary forces between partially immersed bodies -- Lateral capillary forces between floating particles -- Capillary forces between particles bound to a spherical interface -- Mechanics of lipid membranes and interaction between inclusions -- Capillary bridges and capillary-bridge forces -- Capillary forces between particles of irregular contact line -- Two-dimensional crystallization of particulates and proteins -- Effect of oil drops and particulates on the stability of foams.
Author | : Eduardo Guzmán |
Publisher | : MDPI |
Total Pages | : 232 |
Release | : 2021-03-02 |
Genre | : Science |
ISBN | : 3039436333 |
Download Fluid Interfaces Book in PDF, ePub and Kindle
Fluid interfaces are promising candidates for confining different types of materials, e.g., polymers, surfactants, colloids, and even small molecules, to be used in designing new functional materials with reduced dimensionality. The development of such materials requires a deepening of the physicochemical bases underlying the formation of layers at fluid interfaces as well as on the characterization of their structures and properties. This is of particular importance because the constraints associated with the assembly of materials at the interface lead to the emergence of equilibrium and features of dynamics in the interfacial systems, which are far removed from those conventionally found in traditional materials. This Special Issue is devoted to studies on the fundamental and applied aspects of fluid interfaces, and attempts to provide a comprehensive perspective on the current status of the research field.
Author | : Ivana Barackov |
Publisher | : |
Total Pages | : 137 |
Release | : 2013 |
Genre | : |
ISBN | : 9783843915618 |
Download Investigation of protein behavior at gas-liquid interfaces Book in PDF, ePub and Kindle
Author | : Ashley J. Wilson |
Publisher | : Springer Science & Business Media |
Total Pages | : 237 |
Release | : 2013-11-11 |
Genre | : Technology & Engineering |
ISBN | : 1447138074 |
Download Foams: Physics, Chemistry and Structure Book in PDF, ePub and Kindle
Foams and froths are an important feature of everyday life; one only has to think of shaving foam, foam upholstery, fire fighting foam, bread, bear head, and ice cream. Less obvious but equally important are the foams and foaming processes which are being exploited in ever more complex and imaginative ways in industry. However, the unusual nature of foams, the fact that they are neither solids or liquids, and their very fragility has prevented scientists from obtaining a thorough understanding of even the basic principles of foam formation and stability. This volume presents papers on the physics, chemistry, structure and ultrastructure of foams by contributors from a wide range of backgrounds and research disciplines. The aim of the book is to present a unique multi-disciplinary cross section of work currently being undertaken on the subject of foams.