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Prostaglandins and Fertility Regulation

Prostaglandins and Fertility Regulation
Author: M. Toppozada
Publisher: Springer Science & Business Media
Total Pages: 158
Release: 2012-12-06
Genre: Medical
ISBN: 9400956002

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The role of prostaglandins in physiological events and pathological disorders related to human reproduction has been most actively investigated in the past decade. Their clinical use for fertility regulation, extensively evaluated, represents the most common clinical indication for the administration of these remarkable compounds. Thus, it is most appropriate to update the available information related to the use of prostaglandins in the regulation of human fertility to provide a background document for the benefit of clinicians and scientists. Invited experts of international reputation from various parts of the world have contributed, each in his own area of interest, to offer this book, which we hope will fill an existing gap. M. T. M. B. E. S. E. H. ix 1 Potential for prostaglandin use in controlling human reproduction K. T. KIRTON and F. A. KIMBALL BACKGROUND It was observed in 1930 that seminal plasma of a number of species contained very large amounts of substance(s) capable of altering uterine motility. These substances were subsequently demonstrated to be prostaglandins (PGs); this began the early and continued association of this group of compounds with reproduction. The activity was found to be associated with a fraction containing lipid-soluble acids, derived from prostanoic acid. Restrictions imposed by obscure sources and small amounts of material available for testing were initially impediments to their study.


Prostaglandin Abstracts

Prostaglandin Abstracts
Author: Ronald A. Shalita
Publisher: Springer
Total Pages: 472
Release: 1975-01-05
Genre: Medical
ISBN:

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Prostagtandin Abstracts Volume II contains abstracts of the significant scientific Iiterature published in 1971, 1972, and 1973 on the role of prostaglandins in human reproduction. Of the more than 4000 articles which were published between 1971 and 1973 and deal with prostaglandins, endogenous and exogenous, in mal es and females, nearly 1100 involve human reproduction. Prostagtandin Abstracts, Volume I (Plenum Publishers, 1973) contains abstracts of all articles on prostaglandins published between 1906, when the action of these compounds was first noted, and 1970, when clinical research with these compounds was weil underway. Clinical use of prostaglandins during the 1960s proved safe but provided evidence of troublesome side effects. Du ring the 1970s, the development of new analogues, various protocols for international testing, and improved routes of administration indicates that prostaglandins still hold promise as a useful drug in the management of fertility. Research into potential contraceptive and other clinical uses of prostaglandins continues to be an exciting and expanding field of fundamental and clinical research. The citations and abstracts which are included in this volume have been selected and reproduced from POPINFORM, a computerized on-line information retrieval system which includes in its data base more than 25,000 documents on regulation of fertility. Also included as an Appendix is a bibliography (without abstracts) of 1971 -1973 material on aspects of prostaglandin research that do not involve reproduction. This bibliography was prepared by the Upjohn Company of Kalamazoo, Michigan and is printed here with permission.


Population Reports

Population Reports
Author:
Publisher:
Total Pages: 72
Release: 1975
Genre: Abortion
ISBN:

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Prostaglandins in Fertility Control

Prostaglandins in Fertility Control
Author: World Health Organization. Research and training centre on human reproduction, Karolinska institutet
Publisher:
Total Pages: 115
Release: 1973
Genre:
ISBN:

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