Prolactin Disorders PDF Download
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Author | : Nicholas A. Tritos |
Publisher | : Springer |
Total Pages | : 242 |
Release | : 2019-05-06 |
Genre | : Medical |
ISBN | : 3030118363 |
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This unique book will serve as a valuable resource for clinicians and researchers interested in prolactin physiology and pathophysiology and those who are involved in the care of patients with related disorders, including hyperprolactinemia and prolactin-secreting pituitary adenomas. Timely and up-to-date, it opens with a review of the historical aspects of prolactin research and a discussion of pituitary anatomy and physiology. Several chapters examine basic and translational aspects of prolactin physiology, focusing on recent developments and future directions. The main portion of the book is comprised of chapters presenting the clinical aspects of prolactin excess or deficiency, with particular emphasis placed on prolactin-secreting pituitary adenomas and co-secreting tumors. Concluding chapters address prolactin-secreting pituitary adenomas in special populations – women in the preconception period or during pregnancy, children and adolescents, and men – as well as plurihormonal and aggressive adenomas and carcinomas. Written and edited by experts in the field, Prolactin Disorders will be a ready reference for a diverse array of professionals, from basic scientists to clinical investigators and clinicians from several specialties, including specialists in endocrinology, neurosurgery, radiation oncology and neuro-oncology.
Author | : Nelson D. Horseman |
Publisher | : Springer Science & Business Media |
Total Pages | : 406 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1461516838 |
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It is an authentic privilege to have the opportunity to assemble and edit a new volume on "Prolactin," the first in several decades to be devoted to this fascinating hormone in all its aspects. The obvious clinical rationale for understanding prolactin (PRL) is the frequent occurrence of prolactinomas, the most common type of pituitary tumor. Fortunately, medical management of prolactinomas can be based on our under standing of the physiology of hypothalamic control of the lactotroph. Armed with this knowledge, therapies for proiactinomas are highly successful and well tolerated. Be cause of the historical and practical importance of knowledge regarding the hypothala mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation. Chapters focusing on prolactinomas and related clinical issues follow these. PRL is the primary hormone that is responsible for "parental care" in many verte brate species. This reproductive strategy is not unique to mammals, but it has devel oped through evolution to be the central distinguishing feature of the mammalian life cycle. Among the mammals, mice have become the most effective research species in recent years. This can be traced to the development of a wide range of methods for manipulating mouse genetics, and thereby influencing development, physiology and behavior. Mice also provide a profound illustration of the physiological challenges faced in maternity. Female mice undergo a post-partum estrous, and often are both pregnant and lactating simultaneously.
Author | : E. Flückiger |
Publisher | : Springer Science & Business Media |
Total Pages | : 402 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642817211 |
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Lactogenic hormone activity was first observed in bovine pituitary extracts by Stricker and Griiter in 1928, working in Bouin's laboratory in Strasbourg. Since that time prolactin has been shown to exist in anterior pituitary extracts of almost all vertebrate species investigated. Although its biology was extensively studied in many mammalian species, the existence of prolactin in the human was generally doubted, despite the positive evidence produced by such researchers as Pasteels. This can partly be explained by the fact that human growth hormone isolated in 1961, is itself a potent lactogen, in contrast to nonprimate growth hormones, and is present in the normal human pituitary in much greater amounts than prolactin. As a result there was a lag of nearly 10 years until prolactin was unanimously accepted as a hormone of the human pituitary, separate from human growth hormone. In 1970 new bioassay techniques permitted the demonstration of prolactin bioactivity in the serum of postpartum women and galactorrhea patients, and chromatographic methods led to the isolation and purification of human prolactin allowing the establishment of a specific radioimmunoassay for this hormone. This opened the road to the understanding of prolactin physiology and pathophysiology in the human, which has revolutionized clinical neuroendocrinology and reproductive endocrinology. Particularly hyperprolactinemia has turned out to be one of the most common endocrine syndromes.
Author | : George Tolis |
Publisher | : |
Total Pages | : 512 |
Release | : 1983 |
Genre | : Medical |
ISBN | : |
Download Prolactin and Prolactinomas Book in PDF, ePub and Kindle
Author | : Horst-Dieter Dellmann |
Publisher | : Springer Science & Business Media |
Total Pages | : 223 |
Release | : 2013-03-09 |
Genre | : Medical |
ISBN | : 1461566754 |
Download Comparative Endocrinology of Prolactin Book in PDF, ePub and Kindle
The selection of prolactin as the subject of the Midwest Con ference on Endocrinology was not only dictated by the recent ad vances in prolactin research but also by the long tradition in that particular area of Endocrinology in the laboratory of C.W. Turner at the University of Missouri. Therefore, it seems only appropri ate that these proceedings of the Tenth Midwest Conference on En docrinology are dedicated to the memory of this scientist, deceased in August 1975 before completion of this volume, whose pioneer in vestigations have contributed substantially to the advancement of our knowledge in many areas of Endocrinology and who played a major role in the early phases of prolactin research. This volume contains a review of the early studies in Turner's laboratory and the latest results obtained by some of the leading research workers in this area and should be a fitting memory to C.W. Turner. Some of the manuscripts printed here were prepared after the conference was held and include material of more recent origin. Much of the delay in publication was due to the length of time de voted to preparation of these manuscripts. To the other authors and participants, and to Plenum Press, we express our appreciation for their patience and cooperation. We also with to thank Mrs.
Author | : Ludwig M. Auer |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 452 |
Release | : 2015-07-24 |
Genre | : Medical |
ISBN | : 311085385X |
Download Prolactinomas, An interdisciplinary approach Book in PDF, ePub and Kindle
Author | : Jerrold M. Olefsky |
Publisher | : |
Total Pages | : 248 |
Release | : 1986 |
Genre | : Medical |
ISBN | : |
Download Prolactinomas Book in PDF, ePub and Kindle
Author | : Maria Diakonova, PhD |
Publisher | : Springer |
Total Pages | : 286 |
Release | : 2014-12-03 |
Genre | : Medical |
ISBN | : 3319121146 |
Download Recent Advances in Prolactin Research Book in PDF, ePub and Kindle
Recent Advances in Prolactin Research summarizes the current knowledge of prolactin (PRL), PRL receptor, PRL-dependent signaling pathways, the role of PRL in oncogenesis and PRL crosstalk with other oncogenic factors. The chapters are written by experts in these fields and focus on identifying and reviewing timely experimental findings that provide new insights into the expanding role of PRL in the pathophysiology associated with a variety of human conditions. Prolactin is a peptide hormone that is best known for its role in lactation. Prolactin also has an influence on hematopoiesis and angiogenesis, and is involved in the regulation of blood clotting through several pathways. Although PRL was discovered more than 80 years ago, the understanding of PRL signaling and its relationship to various pathologies is still very incomplete. PRL is not only a pituitary hormone with an important role in reproduction, but PRL also acts as a cytokine, modulating a wide variety of physiological processes. For example, data gathered during the last decade have demonstrated that locally produced PRL acts as the autocrine/paracrine factor and plays a contributory role during breast oncogenesis. In fact, the scientific and clinical communities have suggested that the manipulation of the PRL axis may lead to the successful treatment of breast cancer. However, recent work has demonstrated that the role of the PRL axis is much more complex than first envisaged.
Author | : Hiroshi Nagasawa |
Publisher | : CRC Press |
Total Pages | : 344 |
Release | : 2020-04-15 |
Genre | : Medical |
ISBN | : 1000696510 |
Download Prolactin Lesions In Breast Uterus & Prostate Book in PDF, ePub and Kindle
First Published in 1989, this book offers a full, comprehensive guide into prolactin function and the treatment of lesions. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Medicine, and other practitioners in their respective fields.
Author | : H.S. Jacobs |
Publisher | : Springer Science & Business Media |
Total Pages | : 54 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 9401163553 |
Download Prolactinomas and Pregnancy Book in PDF, ePub and Kindle