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Progress in Monogenic Hair Disorders

Progress in Monogenic Hair Disorders
Author: Eli Sprecher
Publisher: Nova Publishers
Total Pages: 252
Release: 2005
Genre: Hair
ISBN: 9781594543616
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In the present monograph, leading figures in the field of genetic hair research summarise major recent advances. View as a whole, these reviews of each of the major areas of hair genodermatology not only illustrate the importance of recent findings to our understanding of skin biology and the management of hair disorders, but also underscore the relevance of hair genetic research to non-cutaneous pathologies. The wealth of recent discoveries combined with the application of emergent technologies to the study of hair biology and diseases have placed this discipline at the forefront of biological research, generating unprecedented challenges for investigative dermatology that are transpiring throughout this new and pioneering book.

Ichthyoses

Ichthyoses
Author:
Publisher: Karger Medical and Scientific Publishers
Total Pages: 154
Release: 2010-01-01
Genre: Medical
ISBN: 3805593945
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The various manifestations of ichthyoses are classified either by their appearance or their molecular genetics. This volume focuses on generalized, inherited disorders of cornification, which constitute an ever-enlarging group of monogenic diseases caused by a large number of genes that affect a broad array of cellular functions. The authors' overview reflects their unique perspective that the clinical phenotype in the inherited ichthyoses mirrors a 'best attempt' by a metabolically compromised epidermis to maintain a barrier sufficiently impermeable for survival in a desiccating external environment. The basis for threats to survival is illuminated, and the systemic problems, including growth failure, also reflect a compromised barrier. A new consensus classification of these disorders is provided, and the distinguishing clinical features of each disorder are described. Further, the latest molecular genetic information is succinctly reviewed with up-to-date and comprehensive references. Yet, the major emphases of this volume are on disease pathogenesis and on the identification of key ultrastructural features. This publication will prove an invaluable aid to dermatologists, pediatric dermatologists and pediatricians dealing with patients with inherited ichthyoses. In addition, clinical geneticists and dermatopathologists will find it interesting reading.

Alopecias - Practical Evaluation and Management

Alopecias - Practical Evaluation and Management
Author: D. Ioannides
Publisher: Karger Medical and Scientific Publishers
Total Pages: 174
Release: 2015-02-26
Genre: Medical
ISBN: 3318027758
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Hair is subject to either intrinsic (i.e. physiological) aging or extrinsic (i.e. premature) aging that can be attributed to external factors. The intrinsic factors can be associated with genetic mechanisms and are subject to individual variations, whereas external factors include ultraviolet radiation, air pollution, smoking, and possibly nutrition. Leading experts have contributed to this book which offers a practical approach to the evaluation and management of various forms of alopecia, including their pathogenesis, the diagnostic procedures involved, medical treatments, and nutritional issues. A completely new surgical technique for hair transplantation that leaves behind sufficient follicle unit tissue to regenerate hairs is also described. Being comprehensive and easy-to-read, this book should be very useful for dermatologists who wish to diagnose and treat their patients with hair problems more effectively.

A Time for Metabolism and Hormones

A Time for Metabolism and Hormones
Author: Paolo Sassone-Corsi
Publisher: Springer
Total Pages: 141
Release: 2016-04-04
Genre: Medical
ISBN: 3319270699
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Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology

Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology
Author: Jyoti Ranjan Rout
Publisher: CRC Press
Total Pages: 741
Release: 2022-04-27
Genre: Science
ISBN: 1000369447
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Biotechnological Advances for Microbiology, Molecular Biology, and Nanotechnology: An Interdisciplinary Approach to the Life Sciences presents cutting-edge research associated with the beneficial implications of biotechnology on human welfare. The volume mainly focuses on the highly demanding thrust areas of biotechnology that are microbiology, molecular biology, and nanotechnology. The book provides a detailed overview of the beneficial roles of microbes and nanotechnology-based engineered particles in biological developments. Also, it highlights the role of epigenetic machinery and redox modulators during the development of diseases. In addition, it provides research on nanotechnology-based applications in tissue engineering, stem cell, and regenerative medicines. Overall, the book provides an extended platform for acquiring the methodological knowledge needed for today’s biotechnological applications, such as DNA methylation, redox homeostasis, CRISPR, nano-based drug delivery systems, proteomics, genomics, metagenomics, bioluminescence, bioreactors, bioremediation, biosensors, etc. Divided into three sections, the book first highlights some recent trends in applied microbiology used in different areas, such as crop improvement, wastewater treatment, drug delivery, healthcare management, and more. The volume goes on to cover some advances in cellular and molecular mechanisms, such as CRISPR technology in biological systems, induced stem cells in disease prevention, integrated omics technology, and others. The volume also explores the indispensable role of nanotechnology in the precisely modulating intricate functioning of an organism in diagnostic and therapy along its application in tissue engineering and regenerative medicine and in food science as well as its role in ecological sustainability. This multidisciplinary volume will be highly valuable for the researchers, scientists, biologists, and faculty and students striving to expand their horizon of knowledge in their respective fields.

IADVL Textbook of Trichology

IADVL Textbook of Trichology
Author: BS Chandrashekar
Publisher: JP Medical Ltd
Total Pages: 585
Release: 2018-06-30
Genre: Medical
ISBN: 935270391X
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Trichology is the science of the structure, function and diseases of the human hair. This book is a comprehensive guide to the diagnosis and treatment of diseases and disorders of the hair and scalp. Divided into six sections, the text begins with an overview of hair and the normal scalp, factors controlling hair growth and changes that occur during the aging process. The next section discusses diagnostic trichology methods including microscopy and trichoscopy. The following chapters detail the diagnosis and treatment of numerous hair disorders covering both clinical and surgical procedures, for common and more complex conditions. A chapter on recent advances in surgical management is included. The final section discusses interdisciplinary issues in the management of hair disorders such as paediatric, psychiatric, gynaecologic and endocrinologic liaison therapy. Each chapter begins with a ‘key messages’ box and concludes with a summary of the topic. The book is highly illustrated with clinical photographs, diagrams and tables. Key points Comprehensive guide to the diagnosis and management of diseases and disorders of the hair and scalp Covers both clinical and surgical treatment methods Features discussion on liaison therapy between different medical disciplines Highly illustrated with clinical photographs, diagrams, tables and boxes

Male Alopecia

Male Alopecia
Author: Ralph M. Trüeb
Publisher: Springer Science & Business Media
Total Pages: 294
Release: 2014-02-13
Genre: Medical
ISBN: 331903233X
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This monograph provides specialists and primary care physicians who are interested in hair with the practical know-how needed to achieve successful management of male alopecia. Guidance is first provided on the examination of hair loss in men, covering such aspects as clinical examination, the role of trichoscopy and the trichogram, laboratory work-up and scalp biopsy. Diagnosis and treatment are then described in depth for a diverse range of conditions involving alopecia. Expert opinion is combined with the results of evidence-based medicine to provide the best current advice, highlighting the synergistic action of combination regimens and adjuvant treatments and explaining the concept of multitargeted treatment. All aspects of follow-up are covered, including compliance issues and expectation management. The role of hair care and cosmetics is also considered, with identification of potential adverse effects as well as benefits.

Surface Antigens: Advances in Research and Application: 2011 Edition

Surface Antigens: Advances in Research and Application: 2011 Edition
Author:
Publisher: ScholarlyEditions
Total Pages: 60
Release: 2012-01-09
Genre: Medical
ISBN: 1464937567
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Surface Antigens: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Surface Antigens in a concise format. The editors have built Surface Antigens: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Surface Antigens in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Surface Antigens: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Female Alopecia

Female Alopecia
Author: Ralph M. Trüeb
Publisher: Springer Science & Business Media
Total Pages: 214
Release: 2013-02-26
Genre: Medical
ISBN: 364235503X
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Few dermatologic problems carry as many emotional overtones as hair loss in women, which is by far the most common hair problem encountered in daily clinical practice. Fortunately, a specific diagnosis can usually be established through the application of appropriate examinations and tests, and treatment suited to the diagnosis is likely to control the problem. This comprehensively illustrated monograph provides both specialists and primary care physicians with the practical know-how required for successful management of hair loss in female patients of all ages. The book opens by critically examining various myths about hair loss. The different examination techniques are then described, and the various forms of hair loss and their treatment are discussed in detail. Approaches to follow-up are outlined, and the management of patient expectations is carefully considered. The potential role of hair care and cosmetics is also explored in some depth.

Health Effects of Exposure to Low Levels of Ionizing Radiation

Health Effects of Exposure to Low Levels of Ionizing Radiation
Author: National Research Council
Publisher: National Academies
Total Pages: 436
Release: 1990-02-01
Genre: Science
ISBN: 0309039959
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This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.