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Progress in Fetal and Neonatal Brain Injury Research

Progress in Fetal and Neonatal Brain Injury Research
Author: Steven W. Levison
Publisher:
Total Pages: 0
Release: 2009
Genre:
ISBN: 9783805592635

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The immature brain is vulnerable to prenatal and postnatal stress, which may produce brain damage leading to neurological dysfunction in survivors. The articles in this special issue provide new insights into the pathophysiology and treatment of developmental brain injuries and functional outcomes. Information obtained using preclinical models as well as data from clinical studies emphasize the influence of hypoxia-ischemia, excitotoxicity, oxidative stress, seizures and inflammatory mediators on the outcome of developmental brain injury and ultimate neurological outcome. Importantly, several papers report preclinical tests of new therapies that show real promise in preventing injury to the developing brain including erythropoietin, melatonin and steroids. This publication will be of interest to both clinicians and basic scientists who are interested in the developing nervous system, its vulnerability to various pathophysiological processes and the eventual consequences for neurologic development.


Fetal and Neonatal Brain Injury

Fetal and Neonatal Brain Injury
Author: David K. Stevenson
Publisher: Cambridge University Press
Total Pages: 855
Release: 2017-12-21
Genre: Medical
ISBN: 1108506127

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Improvements in the detection of fetal and neonatal brain injuries, advances in our understanding of the pathophysiology, cellular and molecular bases of encephalopathy, and new treatment options have all combined to produce significant changes in the management of neonatal brain disorders in the past few years. This new edition of Fetal and Neonatal Brain Injury brings the reader fully up to date with all advances in clinical management and outcome assessment. Updated material includes inflammation focusing in particular on chorioamnionitis and fetal brain injury; genetic brain injury; and expanded sections on cholestasis, diabetes, and thyroid disease. An updated, highly illustrated chapter on structural and functional imaging of the fetal and neonatal brain is also included. An outstanding international team of highly experienced neonatologists and maternal-fetal medicine clinicians have produced a practical, authoritative clinical text that gives clear management advice to all clinicians involved in the treatment of these patients.


Fetal and Neonatal Brain Injury

Fetal and Neonatal Brain Injury
Author: David K. Stevenson
Publisher: Cambridge University Press
Total Pages: 932
Release: 2003-02-06
Genre: Family & Relationships
ISBN: 9780521806916

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Now in its third edition, this is a comprehensive survey of fetal and neonatal brain injury arising from hypoxia, ischemia or other causes. The volume spans a broad range of areas from epidemiology and pathogenesis, through to clinical manifestations and obstetric care, and then on to diagnosis, long-term outcomes, and medico-legal aspects. An important theme running throughout is to highlight scientific and clinical advances that have a role to play in minimising risk, improving clinical care and outcomes.


Acquired Brain Injury in the Fetus and Newborn

Acquired Brain Injury in the Fetus and Newborn
Author: Michael Shevell
Publisher: Mac Keith Press
Total Pages: 0
Release: 2012-12-17
Genre: Medical
ISBN: 9781907655029

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International Reviews of Child Neurology Series No. 13 Given the tremendous advances in the last five years in the understanding of acquired neonatal brain injury and in the care of affected newborn infants, this book provides a timely review for the practising neurologist, neonatologist and pediatrician. The editors take a pragmatic approach, focusing on specific populations encountered regularly by the clinician. They begin by addressing aspects of fetal neurology and the interpretation of fetal imaging studies. They then follow a “bench to bedside” approach to acquired brain injury in the preterm and term newborn infant in the next chapters. The contributors, all internationally recognized clinician scientists, provide the clinician reader with a state-of-the art review in their area of expertise. The final section of the book address special populations and concerns, areas that are largely overlooked in existing neurology textbooks. Each of these areas has seen considerable advances in the last five years and is of increasing relevance to the neurologist and neonatologist clinician. The comprehensive nature of each section (from basic science to acute clinical care to outcomes) should appeal broadly to scientists and allied health professionals working in neonatal neurology. Readership Paediatric neurologists, neonatologists, neurologists and paediatricians, clinicians in child development, child health researchers and allied health professionals (in physiotherapy, occupational therapy, speech therapy and psychology). Trainees in these areas.


Pathogenesis and Prevention of Fetal and Neonatal Brain Injury

Pathogenesis and Prevention of Fetal and Neonatal Brain Injury
Author: Andrew Macnab
Publisher:
Total Pages: 0
Release: 2018
Genre: Electronic books
ISBN:

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Recent advances in the clinical management of at-risk pregnancy and care of the newborn have reduced morbidity and mortality among sick neonates, and improved our knowledge of factors that influence the risks of brain injury. In parallel, the refinement of imaging techniques has added to the ability of clinicians to define the etiology, timing and location of pathologic changes with diagnostic and prognostic relevance to the developing fetus and newborn infant. Abnormalities of brain growth, or injury to the developing brain can occur during pregnancy; during labor and delivery, hypoxia, acidosis and ischemia pose major risks to the fetus. Defined practices for the management of pregnancy and delivery, and evidence-based strategies for care in the newborn period are influencing outcome. However, newborn infants, especially those born prematurely, remain at risk from situations that can cause or worsen brain injury. The literature reviewed here explains the mechanisms and timing of injury, and the importance of hypoxia, ischemia, hypotension and infection; describes current diagnostic strategies, neuroimaging technologies and care entities available; and outlines approaches that can be used to prevent or mitigate brain injury. Some show particular promise, and all are relevant to lowering the incidence and severity of brain damage.


Neonatal Encephalopathy and Neurologic Outcome

Neonatal Encephalopathy and Neurologic Outcome
Author: American College of Obstetricians and Gy
Publisher: American College of Obstetricians and Gynecologists Women's Health Care Physicians
Total Pages: 0
Release: 2014
Genre: Medical
ISBN: 9781934984307

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Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.


Preterm Birth

Preterm Birth
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 791
Release: 2007-05-23
Genre: Medical
ISBN: 030910159X

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The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.


The Epilepsies

The Epilepsies
Author: Chrysostomos P. Panayiotopoulos
Publisher: Springer
Total Pages: 570
Release: 2005
Genre: Medical
ISBN:

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This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.


Advances in Neonatology

Advances in Neonatology
Author: Lucky Jain
Publisher: Clinics: Internal Medicine
Total Pages: 0
Release: 2009
Genre: Medical
ISBN: 9781437705201

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This issue of Pediatric Clinics offers an update on Advances in Neonatology. Guest Editors Drs. Lucky Jain and David Carlton have assembled a panel of world-class experts who offer reviews on topics including Trends in birthing, gestational age, birth weight and mortality in newborns; Late Prematurity; Advances in newborn resuscitation; Approaches to infants with congenital anomalies; Advances in neonatal surgery; Respiratory failure in the term and near term infant; Mechanical ventilation of the newborn; Pulmonary hypertension in the newborn; Bronchopulmonary dysplasia; Extracorporeal membrane oxygenation; Necrotising enterocolitis; Hyperbilirubinemia; Retinopathy of Prematurity; Surgical approaches to an infant with congenital heart disease; Hypoxic ischemic encephalopathy; Neonatal sepsis; and Quality improvement in neonatology.