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PRODUCTION, CHARACTERIZATION AND OPTIMIZATION OF NATTOKINASE

PRODUCTION, CHARACTERIZATION AND OPTIMIZATION OF NATTOKINASE
Author: Dr. Kiran D. Jagtap
Publisher: Ashok Yakkaldevi
Total Pages: 168
Release: 2020-06-10
Genre: Art
ISBN: 1794848215
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The present research work was related to few problems; those were related to near about all sectors. As per the quote “Need is the Mother of Invention”, we partially solved the problem of above mention sectors through our research. Selection of this research work was initiated from patients those have DVT (Deep Vein Thrombosis), Heart Disease, Arteriosclerosis etc. Nattokinase (subtilisin NAT, NK), a potent fibrinolytic enzyme, was primarily isolated from a traditional fermented food “natto” in Japan. The enzyme is a subtilisin-like serine protease composed of 275 amino acid residues and has a molecular weight of 27.7 kDa. Fermented cheese-like food, Natto has been formed by fermentation by inoculating the bacterium Bacillus natto in the boiled soybeans. The resulting nattokinase enzyme is produced when the bacterium acts on the soybeans (Sumi et al., 1987). Nattokinase is a serine end peptidase with a molecular weight of 20,000 Daltons and having isoelectric point (pI) is 8.6. Nattokinase potentiates fibrinolytic activity. In other words, it could dissolve fibrin. Fibrin is a protein involved in the clotting of blood that is polymerized to form a "mesh" that forms a haemostatic plug or clot (in conjunction with platelets). Fibrin is made from fibrinogen and it is a soluble plasma glycoprotein synthesized by the liver. Nattokinase prevents aggregation of red blood cells. Specifically, Nattokinase supports the fibrinolytic clearing system in the body which is responsible for healthy circulation, by helping to break down fibrin protein deposits in the bloodstream to promote and enhance healthy blood flow. Nattokinase facilitates blood flow contributing to healthy circulation and balance to maintain normal blood pressure.

Fermented Foods, Part I

Fermented Foods, Part I
Author: Didier Montet
Publisher: CRC Press
Total Pages: 413
Release: 2016-04-19
Genre: Science
ISBN: 1498740812
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Traditional fermented foods are not only the staple food for most of developing countries but also the key healthy food for developed countries. As the healthy functions of these foods are gradually discovered, more high throughput biotechnologies are being used to promote the fermented food industries. As a result, the microorganisms, process bioc

Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment

Bioprospecting of Enzymes in Industry, Healthcare and Sustainable Environment
Author: Hrudayanath Thatoi
Publisher: Springer Nature
Total Pages: 408
Release: 2021-01-23
Genre: Science
ISBN: 9813341955
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The rapid urbanization and industrialization of developing countries across the globe have necessitated for substantial resource utilization and development in the areas of Healthcare, Environment, and Renewable energy. In this context ,this resourceful book serves as a definitive source of information for the recent developments in application of microbial enzymes in various sectors. It covers applications in fermentation processes and their products, extraction and utilisation of enzymes from various sources and their application in health and biomass conversion for production of value added products. Different chapters discuss various areas of bioprospecting in enzyme technology, and describe why these are the mainstays for industrial production of value added products. The rich compilation of the cutting-edge advances and applications of the modern industrial based techniques hold feasible solutions for a range of current issues in enzyme technology. This book will be of particular interest for scientists, academicians, technical resource persons, engineers and members of industry. Undergraduate and graduate students pursuing courses in the area of industrial biotechnology will find the information in the book valuable. General readers having interest towards biofuels, enzyme technology, fermented food and value added products, phytochemicals and phytopharmaceutical products will also find the book appealing. Readers will discover modern concepts of enzymatic bioprocess technology for production of therapeutics and industrial value added products.

Current Developments in Biotechnology and Bioengineering

Current Developments in Biotechnology and Bioengineering
Author: Ashok Pandey
Publisher: Elsevier
Total Pages: 888
Release: 2016-09-17
Genre: Science
ISBN: 0444636730
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Current Developments in Biotechnology and Bioengineering: Production, Isolation and Purification of Industrial Products provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, focusing on industrial biotechnology and bioengineering practices for the production of industrial products, such as enzymes, organic acids, biopolymers, and biosurfactants, and the processes for isolating and purifying them from a production medium. During the last few years, the tools of molecular biology and genetic and metabolic engineering have rendered tremendous improvements in the production of industrial products by fermentation. Structured by industrial product classifications, this book provides an overview of the current practice, status, and future potential for the production of these agents, along with reviews of the industrial scenario relating to their production. Provides information on industrial bioprocesses for the production of microbial products by fermentation Includes separation and purification processes of fermentation products Presents economic and feasibility assessments of the various processes and their scaling up Links biotechnology and bioengineering for industrial process development

Microbial Functional Foods and Nutraceuticals

Microbial Functional Foods and Nutraceuticals
Author: Vijai Kumar Gupta
Publisher: John Wiley & Sons
Total Pages: 327
Release: 2017-10-30
Genre: Technology & Engineering
ISBN: 1119048974
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Showcases the recent advances in microbial functional food applications across food science, microbiology, biotechnology, and chemical engineering Microbial technology plays a key role in the improvement of biotechnology, cosmeceuticals, and biopharmaceutical applications. It has turned into a subject of expanding significance because new microbes and their related biomolecules are distinguished for their biological activity and health benefits. Encompassing both biotechnology and chemical engineering, Microbial Functional Foods and Nutraceuticals brings together microbiology, bacteria, and food processing/mechanization, which have applications for a variety of audiences. Pharmaceuticals, diagnostics, and medical device development all employ microbial food technology. The book addresses the recent advances in microbial functional foods and associated applications, providing an important reference work for graduates and researchers. It also provides up-to-date information on novel nutraceutical compounds and their mechanisms of action—catering to the needs of researchers and academics in food science and technology, microbiology, chemical engineering, and other disciplines who are dealing with microbial functional foods and related areas. Microbial Functional Foods and Nutraceuticals is: Ground-breaking: Includes the latest developments and research in the area of microbial functional foods and nutraceuticals Multidisciplinary: Applicable across food science and technology, microbiology, biotechnology, chemical engineering, and other important research fields Practical and academic: An important area of both academic research and new product development in the food and pharmaceutical industries Microbial Functional Foods and Nutraceuticals is an ideal resource of information for biologists, microbiologists, bioengineers, biochemists, biotechnologists, food technologists, enzymologists, and nutritionists.

Current Developments in Biotechnology and Bioengineering

Current Developments in Biotechnology and Bioengineering
Author: Amit Kumar Rai
Publisher: Elsevier
Total Pages: 463
Release: 2021-11-30
Genre: Technology & Engineering
ISBN: 0128236434
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Approx.438 pages Approx.438 pages

Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine

Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine
Author: Tapan Kumar Giri
Publisher: Elsevier
Total Pages: 312
Release: 2023-09-15
Genre: Science
ISBN: 0323957943
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Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine is an archival reference for researchers, students and scientists working on hydrogels based on microbial and animal sources. The book contains Information regarding their synthesis, characterization, and applications in the field of drug delivery and regenerative medicine. Each chapter addresses a separate polysaccharide hydrogel and its suitability in drug delivery and/or regenerative medicine. This is a novel resource that brings together a panel of highly accomplished experts in the field of natural polysaccharides to discuss basic causes and specific problems related to drug delivery and regenerative medicine. Presents detailed practical and theoretical concepts Includes fundamentals and methodologies for hydrogel preparation Covers all hydrogels and specific applications in the field of drug delivery and tissue engineering

Microbial Biofilms

Microbial Biofilms
Author: Bakrudeen Abdul
Publisher: CRC Press
Total Pages: 485
Release: 2020-11-05
Genre: Medical
ISBN: 100021561X
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This book provides a broad range of applications and recent advances in the search for biofilm materials in nature. It also explains the future implications for biofilms in the areas of advanced molecular genetics, pharmaceuticals, pharmacology, and toxicology. This book is comprised of 20 chapters from leading experts in the field and it examines immunology and microbiological studies derived from biofilms as well as explores environmental, agricultural, and chemical impacts on biofilms. It is divided into five subdivisions: biofilms and its complications, biofilm infections in human body, detection of biofilm-forming pathogens, antibiofilm chemotherapy, and biofilms production tools in aquaculture. This book may be used as a text or reference for everyone interested in microbial biofilms and their current applications. It is also highly recommended for environmental microbiologists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest. This book includes chapter homework problems and case studies. Powerpoints are also available for adopting instructors. Discusses and clarifies the resource of isolation and chemical properties from biofilms Discusses the latest pharmaceutical, pharmacological, and medicinal approaches toward the treatment of chronic and uncured diseases, such as Alzheimer’s osteoporotic, sexual dysfunction, sleep sickness, allergy treatment, asthma, hair loss, AIDS, hypertension, antiaging, etc. Examines immunology and microbiological studies derived from biofilms Explores environmental, agricultural, and chemical impacts on biofilms. Dr. Bakrudeen Ali Ahmed Abdul is an Associate Professor, the Head of the Department of Biochemistry and Dean of the School of Life Sciences, Centre for Research and Development (CRD), PRIST Deemed University, Vallam, Thanjavur, Tamil Nadu, India. His research areas include the application of plant biochemistry, bioactive compound production, biotechnological methods, development of pharmaceutical products and pharmacological studies.

Advances in Applied Biotechnology

Advances in Applied Biotechnology
Author: Tong-Cun Zhang
Publisher: Springer
Total Pages: 637
Release: 2015-04-03
Genre: Science
ISBN: 3662463180
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At the ICAB 2014, researchers from around the world will gather to discuss the latest scientific research, findings and technologies concerning Microbial Genetics and Breeding, Optimization and Control of Biological Processes, Biological Separation and Biological Purification, and Advances in Biotechnology. This conference will provide a platform for academic exchange on the application of biotechnology between domestic and international universities, research institutes, corporate experts and scholars. The participants will focus on the international development and future trends. The event will lay a solid foundation for addressing key technical challenges in various areas of applied biotechnology, providing opportunities to promote the development and expansion of the biotechnology industry.

Biomolecular Engineering Solutions for Renewable Specialty Chemicals

Biomolecular Engineering Solutions for Renewable Specialty Chemicals
Author: R. Navanietha Krishnaraj
Publisher: John Wiley & Sons
Total Pages: 484
Release: 2021-12-09
Genre: Technology & Engineering
ISBN: 1119771927
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Discover biomolecular engineering technologies for the production of biofuels, pharmaceuticals, organic and amino acids, vitamins, biopolymers, surfactants, detergents, and enzymes In Biomolecular Engineering Solutions for Renewable Specialty Chemicals, distinguished researchers and editors Drs. R. Navanietha Krishnaraj and Rajesh K. Sani deliver a collection of insightful resources on advanced technologies in the synthesis and purification of value-added compounds. Readers will discover new technologies that assist in the commercialization of the production of value-added products. The editors also include resources that offer strategies for overcoming current limitations in biochemical synthesis, including purification. The articles within cover topics like the rewiring of anaerobic microbial processes for methane and hythane production, the extremophilic bioprocessing of wastes to biofuels, reverse methanogenesis of methane to biopolymers and value-added products, and more. The book presents advanced concepts and biomolecular engineering technologies for the production of high-value, low-volume products, like therapeutic molecules, and describes methods for improving microbes and enzymes using protein engineering, metabolic engineering, and systems biology approaches for converting wastes. Readers will also discover: A thorough introduction to engineered microorganisms for the production of biocommodities and microbial production of vanillin from ferulic acid Explorations of antibiotic trends in microbial therapy, including current approaches and future prospects, as well as fermentation strategies in the food and beverage industry Practical discussions of bioactive oligosaccharides, including their production, characterization, and applications In-depth treatments of biopolymers, including a retrospective analysis in the facets of biomedical engineering Perfect for researchers and practicing professionals in the areas of environmental and industrial biotechnology, biomedicine, and the biological sciences, Biomolecular Engineering Solutions for Renewable Specialty Chemicals is also an invaluable resource for students taking courses involving biorefineries, biovalorization, industrial biotechnology, and environmental biotechnology.