Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Proceedings Of The First International Workshop On Accelerator Based Neutron Sources For Boron Neutron Capture Therapy PDF full book. Access full book title Proceedings Of The First International Workshop On Accelerator Based Neutron Sources For Boron Neutron Capture Therapy.
| Author | : Richard J. Wiersema |
| Publisher | : |
| Total Pages | : |
| Release | : 1994* |
| Genre | : |
| ISBN | : |
| Author | : M. Frederick Hawthorne |
| Publisher | : Springer |
| Total Pages | : 1389 |
| Release | : 2013-11-11 |
| Genre | : Medical |
| ISBN | : 1461512859 |
Frontiers in Neutron Capture Therapy contains current research results originally presented at the Eighth International Symposium on Neutron Capture Therapy for Cancer in La Jolla, CA. This comprehensive collection of peer-reviewed manuscripts is showcased in two volumes covering all aspects of the development of this multidisciplinary approach to cancer therapy. Volume I of this work includes clinical results and current progress in treatment planning, neutron sources and dosimetry, while Volume II presents the synthesis, pharmacology and tissue-targeting design of boron compounds, including work on preclinical dosimetry and radiobiology. Intended for researchers and clinicians involved with or interested in new modes of cancer therapy, this volume will also serve as a useful guideline for scientists, students, and practitioners in the field.
| Author | : Otto K. Harling |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 340 |
| Release | : 2013-03-08 |
| Genre | : Medical |
| ISBN | : 1468458027 |
For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan between 1968 and 1989 and overviews of clinical considerations for neutron capture therapy and of the status of tumor targeting chemical agents for Ncr. Five contributed poster papers dealing with NCT beam design and performance were also presented. A rapporteurs' paper was prepared after the Workshop to attempt to summarize the major aspects, issues, and conclusions which resulted from this Workshop. Many people contributed to both the smooth functioning of the Workshop and to the preparation of these proceedings. Special thanks are reserved for Ms. Dorothy K.
| Author | : R. Fairchild |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 363 |
| Release | : 2013-03-09 |
| Genre | : Medical |
| ISBN | : 1468456229 |
Since Locher first suggested Boron Neutron Capture Therapy (BNCT) in 1936, this theoretically ideal system has intrigued investigators. Unfortunately, the first clinical trials between 1951-1961 were not successful. However, they served to implant firmly the seed of BNCT, the growth of which has been carefully nurtured at a number of locations world-wide. This fact is attested to by the ongoing clinical trials in Japan as well as by the presence of researchers from active groups in the ten countries represented at this Workshop. In 1983 and 1985, the first and second international biannual symposia on BNCT were held, in response to a resurgence of interest in this field. In 1986, the DOE sponsored a workshop on NCT, in large part directed toward evaluating the national effort and the various neutron sources available within the United States. It now seems likely, because of various factors including improved neutron beams and boron delivery systems which have made the modality more attractive, that clinical trials will be initiated in the United States within the next few years. This 1988 special workshop, interspersed between the biannual international symposia, represents an effort to seek ideas and advice on the clinical a~pects of BNCT, from all those diverse groups with a national commitment to this project. Our purpose is to facilitate our endeavor to incorporate the best procedures and techniques in the upcoming clinical trials.
| Author | : Michael Christian Dobelbower |
| Publisher | : |
| Total Pages | : 438 |
| Release | : 1997 |
| Genre | : |
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| Author | : Andrew E. Hawk |
| Publisher | : |
| Total Pages | : 236 |
| Release | : 2003 |
| Genre | : |
| ISBN | : |
| Author | : Börje Larsson |
| Publisher | : |
| Total Pages | : 640 |
| Release | : 1997 |
| Genre | : Boron-neutron capture therapy |
| ISBN | : |
| Author | : Leonard L. Gunderson |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 1665 |
| Release | : 2011-09-16 |
| Genre | : Medical |
| ISBN | : 1455726036 |
With thorough updates throughout, Clinical Radiation Oncology provides the most comprehensive, authoritative, and up-to-date information available for treating patients with cancer. From a multidisciplinary perspective, this new edition, edited by Drs. Leonard L. Gunderson and Joel E. Tepper, examines the therapeutic management of specific disease sites based on both single-modality and combined-modality approaches - providing you with the well-rounded, cutting-edge guidance you need to offer the most effective treatments. A consistent chapter format, full-color design, and access to the full text at www.expertconsult.com make reference fast and easy. It is an ideal resource for mastering the latest, most effective techniques and modalities! Deepen your knowledge with a comprehensive, clinical approach to the scientific foundations of radiation oncology and general oncology as well as state-of-the-art techniques and modalities. Implement a multidisciplinary, "team care" approach to providing intricate treatment plans for patients, often in conjunction with medical oncologists, and surgeons. Broaden your understanding of the basic biology of the disease processes. Examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Quickly and easily find critical information thanks to an easily accessible, full-color design with over 800 color figures that clearly depict treatment techniques. Get broad multimodality perspectives and unique insights from a diverse team of respected editors and contributors –many of whom are new to this edition – affiliated with institutions across North America and internationally Access the fully searchable text anywhere, anytime at www.expertconsult.com, along with references, additional images and tables, video clips and more! Stay current with comprehensive updates throughout that include a new chapter on survivorship issues, and additional video clips on treatments such as prostate and penile cancer brachytherapy. Improve outcomes by providing the most effective treatment for each patient with expanded coverage of new modalities and treatment regimens. Understand and comply with the latest staging guidelines.
| Author | : Hsinshun (Terry) Wu |
| Publisher | : |
| Total Pages | : 312 |
| Release | : 1992 |
| Genre | : Boron-neutron capture therapy |
| ISBN | : |
| Author | : Rajat Kudchadker |
| Publisher | : |
| Total Pages | : 418 |
| Release | : 1996 |
| Genre | : Boron-neutron capture therapy |
| ISBN | : |
Boron Neutron capture therapy (BNCT) is a form of radiation therapy in which nuclides having a high tendency for capturing thermal neutrons, react by emitting charged particles of short range and leaving essentially no residual radioactivity. If these capture nuclides are selectively introduced into the tumor cells, it is theoretically possible to destroy only the tumor and in the process spare the neighboring healthy tissue. Currently, reactors are the only known source of neutrons being used for BNCT. A number of studies have been done using Monte Carlo computer codes such as MCNP to determine an optimum design of a moderator reflector configuration for an accelerator based neutron source utilizing the Li-7(p, n)Be-7 reaction. To confirm this, benchmark experiments were conducted using both a 2.0 MeV Radio Frequency Quadrupole (RFQ) accelerator and a 2.0 MeV Van de Graaff generator. All previous studies had concluded that 2.5 MeV protons would be optimum, which produces neutron having a maximum energy of 787 keV. For BNCT the desired neutron energies are between 1 eV and nominally 10 keV, i.e. in the epithermal region. These neutrons must hence be moderated to bring them down to the desired energy range. The moderator-reflector assemblies for reactor neutrons or those from 2.5 MeV protons on lithium require a little less than a meter of material to achieve the desired neutron spectrum. This research work focuses on using protons with energies just above the Li-7(p, n)Be-7 reaction threshold. These lower energy protons produce neutrons with a maximum energy of just a few hundred keV requiring much less moderation as compared to the 2.5 MeV proton lithium source. The penalty for the low energy neutron spectrum is the low yield of neutrons per proton as compared to the 2.5 MeV protons on lithium. But, less moderation implies that the patient can be moved closer to the lithium target (neutron source), thus making a more efficient use of the source neutrons. This would partially or wholly compensate for the lower yield per proton. In addition the smaller moderator-reflector assembly would result in less scattering occurring, thereby not degrading the forward directional quality of the beam as much as in current assemblies designed for use with the 2.5 MeV protons on a lithium target.
