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Principles of Molecular Regulation

Principles of Molecular Regulation
Author: P. Michael Conn
Publisher: Springer Science & Business Media
Total Pages: 464
Release: 2000-07-28
Genre: Medical
ISBN: 1592590322

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With the dramatic growth in our knowledge of hormone action and the mechanisms of cell regulation, the need for an up-to-date broad-ranging survey of these processes has become pressing. In Principles of Molecular Regulation, P. Michael Conn and Anthony Means have successfully assembled a panel of leading investigators to provide an integrated review of the key areas-membrane receptor-initiated cell signaling and nuclear receptor-initiated gene regulation. Chosen for the excellence of their research as well as their demonstrated writing skills, these distinguished authors illuminate the molecular machinery underlying the regulatory processes of cells. In addition to their comprehensive review of the signaling mechanisms involving cell surface receptors, nuclear receptors, and ion channels, they detail the roles of calcium, lipids, cyclic AMP, protein kinases, and protein phosphatases. They also discuss the molecular regulation of cell proliferation and death, as well as the impact of new technologies on rational drug discovery. Capturing the excitement now present at this vibrant union of molecular biology, cell biology, and endocrinology, Principles of Molecular Regulation constitutes a major new resource for understanding the many and complex elements of biological regulation. Its up-to-date critical synthesis is certain to prove of high value to all basic and clinical investigators working with these processes today.


Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Molecular Biology of the Cell 6E - The Problems Book

Molecular Biology of the Cell 6E - The Problems Book
Author: John Wilson
Publisher: Garland Science
Total Pages: 984
Release: 2014-11-21
Genre: Science
ISBN: 1317497279

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The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has be


Molecular Biology

Molecular Biology
Author: Nancy Craig
Publisher: Oxford University Press
Total Pages: 945
Release: 2014-05
Genre: Science
ISBN: 0199658579

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The biological world operates on a multitude of scales - from molecules to tissues to organisms to ecosystems. Throughout these myriad levels runs a common thread: the communication and onward passage of information, from cell to cell, from organism to organism and ultimately, from generation to generation. But how does this information come alive to govern the processes that constitute life? The answer lies in the molecular components that cooperate through a series of carefully-regulated processes to bring the information in our genome to life. These components and processes lie at the heart of one of the most fascinating subjects to engage the minds of scientists today: molecular biology. Molecular Biology: Principles of Genome Function, Second Edition, offers a fresh approach to the teaching of molecular biology by focusing on the commonalities that exist between the three kingdoms of life, and discussing the differences between the three kingdoms to offer instructive insights into molecular processes and components. This gives students an accurate depiction of our current understanding of the conserved nature of molecular biology, and the differences that underpin biological diversity. Additionally, an integrated approach demonstrates how certain molecular phenomena have diverse impacts on genome function by presenting them as themes that recur throughout the book, rather than as artificially separated topics As an experimental science, molecular biology requires an appreciation for the approaches taken to yield the information from which concepts and principles are deduced. Experimental Approach panels throughout the text describe research that has been particularly valuable in elucidating difference aspects of molecular biology. Each panel is carefully cross-referenced to the discussion of key molecular biology tools and techniques, which are presented in a dedicated chapter at the end of the book. Molecular Biology further enriches the learning experience with full-color artwork, end-of-chapter questions and summaries, suggested further readings grouped by topic, and an extensive glossary of key terms. Features: A focus on the underlying principles of molecular biology equips students with a robust conceptual framework on which to build their knowledge An emphasis on their commonalities reflects the processes and components that exist between bacteria, archae, and eukaryotes Experimental Approach panels demonstrate the importance of experimental evidence by describing research that has been particularly valuable in the field


In the Light of Evolution

In the Light of Evolution
Author: National Academy of Sciences
Publisher:
Total Pages: 388
Release: 2007
Genre: Science
ISBN:

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The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.


Molecular Imaging

Molecular Imaging
Author: Brian D. Ross
Publisher: Academic Press
Total Pages: 1872
Release: 2021-08-03
Genre: Science
ISBN: 0128163879

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The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications


Principles of Molecular Virology

Principles of Molecular Virology
Author: Alan Cann
Publisher: Elsevier
Total Pages: 340
Release: 2005-07-26
Genre: Medical
ISBN: 9780120887897

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"Principles of Molecular Virology, Fourth Edition" provides an essential introduction to modern virology in a clear and concise manner. It is a highly enjoyable and readable text with numerous illustrations that enhance the reader's understanding of important principles. It contains new material on virus structure, virus evolution, zoonoses, bushmeat, SARS and bioterrorism. The standard version includes a CD-ROM with Flash animations, virtual interactive tutorials and experiments, self-assessment questions, useful online resources, along with the glossary, classification of subcellular infectious agents and history of virology.


Principles of Cell and Molecular Biology

Principles of Cell and Molecular Biology
Author: Lewis J. Kleinsmith
Publisher: Benjamin Cummings
Total Pages: 904
Release: 1995
Genre: Science
ISBN:

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A balanced treatment of both classical cell biology and modern molecular biology issues. This second edition has been revised to update all scientific content and references. Developed to be a readable story that is accessible, interesting and comprehensible for all introductory students the authors provide a balanced treatment of both classical cell biology and modern molecular biology issues. Students are further presented with historical and experimental approaches to explain the evolution of models and ideas, and to provide actual data for each concept.


Cell Signaling

Cell Signaling
Author: Wendell Lim
Publisher: Taylor & Francis
Total Pages: 412
Release: 2014-06-16
Genre: Science
ISBN: 1317573625

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Cell Signaling presents the principles and components that underlie all known signaling processes. It provides undergraduate and graduate students the conceptual tools needed to make sense of the dizzying array of pathways used by the cell to communicate. By emphasizing the common design principles, components, and logic that drives all signa


Epigenetic Gene Expression and Regulation

Epigenetic Gene Expression and Regulation
Author: Suming Huang
Publisher: Academic Press
Total Pages: 484
Release: 2015-10-19
Genre: Science
ISBN: 0128004711

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Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples. Reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies Helps readers understand how epigenetic marks are targeted, and to what extent transgenerational epigenetic changes are instilled and possibly passed onto offspring Chapters are replete with clinical examples to empower the basic biology with translational significance Offers more than 100 illustrations to distill key concepts and decipher complex science