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| Author | : Hyun Kook Lim |
| Publisher | : Frontiers Media SA |
| Total Pages | : 99 |
| Release | : 2020-08-05 |
| Genre | : |
| ISBN | : 2889639177 |
| Author | : Hyun Kook Lim |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2020 |
| Genre | : |
| ISBN | : |
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 181 |
| Release | : 2017-09-05 |
| Genre | : Medical |
| ISBN | : 0309459621 |
Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.
| Author | : C.A. Raji |
| Publisher | : IOS Press |
| Total Pages | : 674 |
| Release | : 2024-02-20 |
| Genre | : Medical |
| ISBN | : 1643684930 |
It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of modifiable risk factors associated with the disease has been present from the outset. Thus, the idea of preventing AD is not new, with reference to strategies noted as early as the 1990s. This subfield of AD research has matured in recent years, with the number of modifiable risk factors – the AD preventome – rising from the 7 initially identified to the current 12, with an estimated contribution to dementia cases worldwide of about 40%. This book, the Handbook of Prevention and Alzheimer’s Disease, introduces physicians, scientists, and other stakeholders to this subfield of AD research. It investigates the AD preventome, which will continue to expand as the understanding of new factors and related biomarkers is refined. Optimizing this preventome leads to an improvement in overall brain health, an outcome which reduces the risk of developing AD and improves quality of life. The book goes on to examine other domains of prevention, from vascular risk factors to social engagement and from sleep health to spirituality. If the journey to end AD can be likened to a long and arduous challenge, understanding every possible part of the overall toolkit of approaches for disease prevention and intervention is essential. Together with its companion volume on intervention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: White matter tracts showing sex differences in connectivity in men versus women as a function of increasing body mass index. Reprinted with permission from Rahmani F, Wang Q, McKay NS, Keefe S, Hantler N, Hornbeck R, Wang Y, Hassenstab J, Schindler S, Xiong C, Morris JC, Benzinger TLS, Raji CA. Sex-Specific Patterns of Body Mass Index Relationship with White Matter Connectivity. J Alzheimers Dis. 2022;86(4):1831-1848. doi: 10.3233/JAD-215329. PMID: 35180116; PMCID: PMC9108572.
| Author | : C.A. Raji |
| Publisher | : IOS Press |
| Total Pages | : 768 |
| Release | : 2024-02-22 |
| Genre | : Medical |
| ISBN | : 1643685015 |
It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of managing some of the modifiable risk factors associated with the disease has been present from the outset. Intervening to manage risk factors as a way of tackling AD is not new, but optimizing brain health as a way of minimizing risk and maximizing the potential benefits of revolutionary new treatments for AD is becoming increasingly important. This book, the Handbook of Intervention and Alzheimer’s Disease, presents 47 papers exploring factors which may either inspire or inform future treatment and clinical trials. While novel interventions such as anti-amyloid immunotherapy present great opportunities, they may also increase the risk of brain bleeds and edema, which in turn may lead to adverse clinical outcomes. Such adverse outcomes are demonstrably more likely to occur in persons with poor brain health, so improved management of the risk factors which make up the AD preventome will also minimize the risks associated with such novel therapies. The papers in this volume can therefore be thought of as offering insight into those factors that can optimize brain health or providing key insights into interventions which may achieve such outcomes. Together with its companion volume on prevention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: Improved hypoperfusion (resolving blue colors) on ASL MRI Z-score maps superimposed on structural MRI scans at baseline and one year in a PET amyloid-positive research participant with cognitive complaints undergoing one year of multi-domain personalized brain health interventions (vascular disease management, dietary optimization, sustained physical activity etc.). Permission to use this figure was granted both by the study P.I. Dr. David Merrill, MD, PhD, of the Pacific Neuroscience Institute and the research participant.
| Author | : Jack C. de la Torre |
| Publisher | : Springer |
| Total Pages | : 256 |
| Release | : 2016-06-25 |
| Genre | : Medical |
| ISBN | : 3319340573 |
This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
| Author | : Dean Sherzai |
| Publisher | : Simon and Schuster |
| Total Pages | : 449 |
| Release | : 2017-10-05 |
| Genre | : Health & Fitness |
| ISBN | : 1471162796 |
THE HIGHLY SUCCESSFUL, PROVEN PROGRAMME FOR REVERSING THE SYMPTOMS OF ALZHEIMER'S DISEASE Alzheimer's Disease affects over 47 million people worldwide but 90 per cent of cases can be prevented. Based on the largest clinical study to date, The Alzheimer's Solution, by leading neurologists and Alzheimer's specialists Drs Dean and Ayesha Sherzai, provides the essential practical tools you and your family need to reverse the symptoms and prevent cognitive decline. Alzheimer's disease isn't a genetic inevitability and a diagnosis doesn’t need to spell the end. Ninety per cent of us can avoid getting it and for the 10 per cent with strong genetic risk, the disease can be delayed by 10 to 15 years. This is based on the remarkable results Dr Dean Sherzai and Dr Ayesha Sherzai have seen in their own clinic. This much-needed revolutionary book provides: *The groundbreaking and successful programme for the treatment of Alzheimer's *A practical 5-part plan for reversing and preventing Alzheimer's, covering food, sleep, exercise, stress-management and activities that keep your brain healthy *A questionnaire for assessing your risk level and daily guides for optimising your brain's health *Delicious and simple brain-healthy recipes for you and the family to enjoy Praise for The Alzheimer's Solution: 'The Sherzais' research is changing the landscape of neurodegenerative diseases as well as the outcomes for thousands of patients.' Dr Keith Black, Chairman of the Neurosurgery Department and Director of the Maxine Dunitz Neurological Institute, Cedars-Sinai Medical Center 'A very important book.' Dr Dilip Jeste, Distinguished Professor of Psychiatry and Neurosciences, University of California, San Diego School of Medicine 'The Alzheimer’s Solution supplies everything you need to know about the prevention of this disease' Dr Joel Fuhrman, New York Times best-selling author of Super Immunity, Eat to Live and The End of Diabetes, President, Nutritional Research Foundation 'This [is a] thorough, thoughtful, empowering, and timely book…Every family should own, and apply, The Alzheimer’s Solution.' Dr David Katz, founding director of Yale University's Yale-Griffin Prevention Research Center, founder and president of the True Health Initiative, and author of Disease-Proof
| Author | : Richard S. Isaacson, MD |
| Publisher | : Square One Publishers, Inc. |
| Total Pages | : 251 |
| Release | : 2016-05-19 |
| Genre | : Health & Fitness |
| ISBN | : 0757054080 |
*** OVER 13,000 COPIES SOLD *** SEEN NATIONWIDE ON THE DR. OZ SHOW Increasingly, research has shown that diet is one of the greatest weapons we have to protect and defend your rain against Alzheimer’s disease (AD). Based on current studies as well as firsthand experience working with thousands of patients—both those who have normal cognitive health and those in the early stages of Alzheimer’s—The Alzheimer’s Prevention & Treatment Diet provides a cutting-edge nutritional program that can help reduce the risk for AD and may slow its progress if it has already developed. This book: * Presents a nine-week diet plan that gradually introduces brain-healthy foods and dietary strategies. * Guides you in making smart lifestyle choices, from exercise to hobbies, that strengthen cognitive health. * Explores nutritional supplements that can support the brain and prevent cognitive decline. * Offers suggestions for managing the special nutritional needs of loved ones with AD. * Explains the medications used to treat AD—what they are, what they do, and how they should be used. * Provides sample full-day menus, including breakfast, lunch, dinner, and snacks. * Presents lists of recommended foods to make meal planning easy. Whatever your age, now is the perfect time to start adopting a brain-healthy lifestyle. The Alzheimer’s Prevention and Treatment Diet guides you in making changes that can significantly enhance your cognitive well-being—now and for a lifetime.
| Author | : Panayiotis Vlamos |
| Publisher | : Springer Nature |
| Total Pages | : 391 |
| Release | : 2022-01-01 |
| Genre | : Medical |
| ISBN | : 3030787710 |
The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.
| Author | : National Academies of Sciences Engineering and Medicine |
| Publisher | : |
| Total Pages | : |
| Release | : 2022-04-26 |
| Genre | : |
| ISBN | : 9780309495035 |
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
