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Precision Medicine in Cardiovascular Disease Prevention

Precision Medicine in Cardiovascular Disease Prevention
Author: Seth S. Martin
Publisher: Springer Nature
Total Pages: 194
Release: 2021-07-07
Genre: Medical
ISBN: 3030750558

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This book contains the current knowledge and potential future developments of precision medicine techniques including artificial intelligence, big data, mobile health, digital health and genetic medicine in the prevention of cardiovascular disease. It reviews the presently used advanced precision medicine techniques and fundamental principles that continue to act as guiding forces for many medical professionals in applying precision and preventative medical techniques in their day-to-day practices. Precision Medicine in Cardiovascular Disease Prevention describes current knowledge and potential future developments in this rapidly expanding field. It therefore provides a valuable resource for all practicing and trainee cardiologists looking to develop their knowledge and integrate precision medicine techniques into their practices.


Personalized and Precision Integrative Cardiovascular Medicine

Personalized and Precision Integrative Cardiovascular Medicine
Author: Mark Houston
Publisher: Lippincott Williams & Wilkins
Total Pages: 1201
Release: 2019-10-08
Genre: Medical
ISBN: 1975115295

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Encompassing functional cardiology, integrative medicine, and metabolic medicine/cardiology, this unique reference offers an up-to-date, expert approach to heart health wellness and treating the diseased heart and blood vessels. It provides today’s practitioners with insight into various treatment options and alternatives to pharmaceutical care and surgery, incorporating new scientific information on metabolic and integrative cardiovascular medicine from peer-reviewed articles, evidence-based medicine, and human clinical research as a foundation for practical clinical information.


Sex-Specific Analysis of Cardiovascular Function

Sex-Specific Analysis of Cardiovascular Function
Author: Peter L. M. Kerkhof
Publisher: Springer
Total Pages: 725
Release: 2018-07-26
Genre: Medical
ISBN: 331977932X

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This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.


Preventive Cardiology: A Companion to Braunwald's Heart Disease E-Book

Preventive Cardiology: A Companion to Braunwald's Heart Disease E-Book
Author: Roger Blumenthal
Publisher: Elsevier Health Sciences
Total Pages: 632
Release: 2011-02-25
Genre: Medical
ISBN: 1437737854

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Endorsed by the American Society for Preventive Cardiology! Preventive Cardiology - a new Companion to Braunwald’s Heart Disease - addresses the prevention and risk stratification of cardiovascular disease so that you can delay the onset of disease and moderate the effects and complications. Drs. Roger Blumenthal, JoAnne Foody, and Nathan Wong discuss the full range of relevant considerations, including the epidemiology of heart disease, risk assessment, risk factors, multiple risk factor-based prevention strategies, and developments in genetics and personalized medicine. This authoritative reference gives you the clinically relevant information you need for the effective prevention of cardiovascular disease. Recognize the factors for prevention and risk stratification around cardiovascular disease and effectively delay the onset of disease and moderate the effects and complications, even for individual who are genetically predisposed. Effectively navigate full range of considerations in prevention from epidemiology of heart disease, biology of atherosclerosis and myocardial infraction, risk assessment—established risk factors and emerging risk factors, multiple risk factor-based prevention strategies, and future directions—through genetics, personalized medicine, and much more. Tap into the expertise of prominent leaders in cardiovascular disease prevention with guidance from Drs. Roger Blumenthal—longtime director of the Framingham Heart Study—JoAnne Foody, and Nathan Wong. Gain a deeper understanding of the pathogenesis of disease and the rationale for management through discussions of basic science. Apply current clinical practice guidelines to ensure optimal outcomes in both primary and secondary prevention.


Prevention of Cardiovascular Disease: A Continuum, An Issue of Cardiology Clinics - E-Book

Prevention of Cardiovascular Disease: A Continuum, An Issue of Cardiology Clinics - E-Book
Author: Prakash C. Deedwania
Publisher: Elsevier Health Sciences
Total Pages: 192
Release: 2011-03-01
Genre: Medical
ISBN: 1455709085

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With the numerous advances that have been made in treatment of heart disease over the past 20 years, physicians are now emphasizing more than ever the prevention of heart disease. This issue provides cardiologists with practical state-of-the-art information on prevention that can be be easily applied to their patients. Topics covered include diabetes, lipid-lowering therapy, RAAS blockade, emerging therapies for atherosclerosis prevention, and heart disease in women.


Economic Dimensions of Personalized and Precision Medicine

Economic Dimensions of Personalized and Precision Medicine
Author: Ernst R. Berndt
Publisher: University of Chicago Press
Total Pages: 361
Release: 2019-04-22
Genre: Business & Economics
ISBN: 022661123X

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Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.


Toward Precision Medicine

Toward Precision Medicine
Author: National Research Council
Publisher: National Academies Press
Total Pages: 142
Release: 2012-01-16
Genre: Medical
ISBN: 0309222222

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Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.


Molecular Cardiology

Molecular Cardiology
Author: Zhongjie Sun
Publisher: Springer Science & Business Media
Total Pages: 410
Release: 2008-02-01
Genre: Medical
ISBN: 159259879X

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The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.


Genomic and Precision Medicine

Genomic and Precision Medicine
Author: Geoffrey S. Ginsburg
Publisher: Academic Press
Total Pages: 379
Release: 2022-04-09
Genre: Science
ISBN: 0128006536

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Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice Covers case studies that highlight the practical use of genomics in the management of patients


Integrative Cardiovascular Chinese Medicine

Integrative Cardiovascular Chinese Medicine
Author: Anika Niambi Al-Shura
Publisher: Academic Press
Total Pages: 354
Release: 2014-06-11
Genre: Medical
ISBN: 012420077X

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Combining the research and study of integrative Chinese and Western Medicine, Integrative Cardiovascular Chinese Medicine: A Prevention and Personalized Medicine Perspective presents a clear, structured base to guide clinical practice and encourage collaboration between Chinese medicine and Western medicine practitioners. This complete reference work thoroughly covers the pathophysiology of cardiology-related diseases, and compares, juxtaposes, and integrates Western and traditional Chinese medicine (TCM). Anika Niambi Al-Shura provides a realistic scope of cardiology treatment and the integration of Western and Chinese medicine, establishing a basis for standardization and a rationale for the inclusion of TCM in cardiology, and identifying and inspiring ideas for future research. Integrates Western and Chinese medicine for a realistic scope of cardiology treatment Establishes basis for standardization and rationale for the inclusion of traditional Chinese medicine in cardiology "Clinical pearls" provide a guiding base of traditional Chinese medicine in clinical use Offers a reference section that lists the latest in published studies Presents easy access to the medicines and herbs used in both Chinese and Western medicine, including photos and information about the current patents