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| Author | : A. Lima-de-Faria |
| Publisher | : World Scientific |
| Total Pages | : 428 |
| Release | : 2008 |
| Genre | : Science |
| ISBN | : 9812814795 |
Contains information on the molecular organization of the chromosome. This book is suitable for those in the biotechnological industry.
| Author | : Soraya de Chadarevian |
| Publisher | : University of Chicago Press |
| Total Pages | : 318 |
| Release | : 2020-07-02 |
| Genre | : Science |
| ISBN | : 022668511X |
By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. Telling this history in full for the first time, Soraya de Chadarevian argues that the often bewildering variety of observations made under the microscope were central to the study of human genetics. Making space for microscope-based practices alongside molecular approaches, de Chadarevian analyzes the close connections between genetics and an array of scientific, medical, ethical, legal, and policy concerns in the atomic age. By exploring the visual evidence provided by chromosome research in the context of postwar biology and medicine, Heredity under the Microscope sheds new light on the cultural history of the human genome.
| Author | : Antonio Lima-de-Faria |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 171 |
| Release | : 2012-03-19 |
| Genre | : Science |
| ISBN | : 3642253016 |
After having read this book you will never see birds in the same way again. The unexpected patterns displayed by a bird’s body have been seen as bizarre events that demanded little attention or were described as ‘amazing curiosities’. None of these surprising features seem to be fortuitous. They appear to be an integral part of a rigid order and a coherent geometry, which is directed by simple gene interactions and molecular cascades occurring at various cellular levels, and at different times, during the organism’s development. A novel geometry unfolds in front of your eyes, giving the body configurations another meaning. Lima-de-Faria is Professor Emeritus of Molecular Cytogenetics at Lund University, Lund, Sweden. This is his sixth book dealing with the molecular organization of the chromosome and its implications for the understanding of the mechanisms responsible for biological evolution.
| Author | : Suzan Mazur |
| Publisher | : North Atlantic Books |
| Total Pages | : 378 |
| Release | : 2010 |
| Genre | : Body, Mind & Spirit |
| ISBN | : 1556439245 |
A new theory of evolution begins to emerge in the pages of The Altenberg 16: An Expos of the Evolution Industry. Written by Suzan Mazur--a print and television journalist whose reports have appeared in the Financial Times, The Economist, Archaeology, Omni, and many other publications--the book is a front row seat to the thinking of the great evolutionary science minds of our time about the need to reformulate the neo-Darwinian theory of evolution. We hear from world renowned scientists such as Richard Lewontin, Lynn Margulis, Niles Eldredge, Richard Dawkins, the "evo-devo" revolutionaries, NASA astrobiologists, and others. The book grew out of a story Mazur broke online in March 2008--titled "Altenberg The Woodstock of Evolution?"--about the now famous meeting at Konrad Lorenz Institute in Altenberg, Austria in July 2008, where 16 scientists discussed expanding evolutionary thinking beyond outdated hypotheses. (MIT will publish the proceedings in April 2010.) Science magazine noted that Mazur's reporting "reverberated throughout the evolutionary biology community." Mazur says she was punished for getting out in front of the story and banned from the symposium but realized the story was bigger than Altenberg (which covered events beginning 500 million years ago) and spoke to scientists who were not invited, including those investigating pre-biotic evolution. She came to the conclusion that evolutionary science suffers because many in the scientific establishment refuse to acknowledge that the old science has served its purpose and there is disagreement about what the new evolution paradigm is. She thinks the dam is now breaking because the public (who funds science) has become a party to the discourse via the Internet and seeks answers to fundamental questions about evolution that scientists so far can't definitively answer.
| Author | : John Modrow |
| Publisher | : iUniverse |
| Total Pages | : 77 |
| Release | : 2011-12-16 |
| Genre | : Philosophy |
| ISBN | : 1462070213 |
The Triumph of the Necrophiles is the product of over forty years of research and is the most thorough, comprehensive, and penetrating critique of the mechanical worldview ever written. Modrow meticulously traces the prescientific sources of that worldview back to our Judeo-Christian heritage and to the metaphysics of Plato and Pythagoras. He documents that Plato was in fact a necrophile and that his metaphysics can best be understood as a sublimation of his necrophilia. He discusses the influence that Plato and Pythagoras had on Copernicus, Kepler and Galileo. He especially emphasizes how the necrophilic worldview of Plato essentially became the worldview of Galileo, Descartes, and other seventeenth- century thinkers. He also discusses how Newton’s worldview was shaped by his religious beliefs. Modrow contends that the mechanical worldview is totally at odds with every major scientific advance that has occurred since the mid nineteenth century. He painstakingly explains how and why these scientific advances discredit that worldview. He discusses the philosophical implications of the theory of evolution, the theory of relativity, quantum theory, Bell’s theorem, and Godel’s proof and presents an alternative worldview that is more consistent with current scientific knowledge. In a final chilling chapter, Modrow shows where the necrophilic worldview of Plato and his modern mechanistic followers are taking us.
| Author | : Antonio Lima-de-Faria |
| Publisher | : Springer |
| Total Pages | : 188 |
| Release | : 2014-10-07 |
| Genre | : Science |
| ISBN | : 3319060562 |
New concepts arise in science when apparently unrelated fields of knowledge are put together in a coherent way. The recent results in molecular biology allow to explain the emergence of body patterns in animals that before could not be understood by zoologists. There are no ”fancy curiosities” in nature. Every pattern is a product of a molecular cascade originating in genes and a living organism arises from the collaboration of these genes with the outer physical environment. Tropical fishes are as startling in their colors and geometric circles as peacocks. Tortoises are covered with the most regular triangles, squares and concentric circles that can be green, brown or yellow. Parallel scarlet bands are placed side by side of black ones along the body of snakes. Zebras and giraffes have patterns which are lessons in geometry, with their transversal and longitudinal stripes, their circles and other geometric figures. Monkeys, like the mandrills, have a spectacularly colored face scarlet nose with blue parallel flanges and yellow beard. All this geometry turns out to be highly molecular. The genes are many and have been DNA sequenced. Besides they not only deal with the coloration of the body but with the development of the brain and the embryonic process. A precise scenario of molecular events unravels in the vertebrates. It may seem far-fetched, but the search for the origin of this geometry made it mandatory to study the evolution of matter and the origin of the brain. It turned out that matter from its onset is pervaded by geometry and that the brain is also a prisoner of this ordered construction. Moreover, the brain is capable of altering the body geometry and the geometry of the environment changes the brain. Nothing spectacular occurred when the brain arrived in evolution. Not only it came after the eye, which had already established itself long ago, but it had a modest origin. It started from sensory cells on the skin that later aggregated into clusters of neurons that formed ganglia. It also became evident that pigment cells, that decide the establishment of the body pattern, originate from the same cell population as neurons (the neural crest cells). This is a most revealing result because it throws light on the power that the brain has to rapidly redirect the coloration of the body and to change its pattern. Recent experiments demonstrate how the brain changes the body geometry at will and within seconds, an event that could be hardly conceived earlier. Moreover, this change is not accidental it is related to the surrounding environment and is also used as a mating strategy. Chameleons know how to do it as well as flat fishes and octopuses. No one would have dared to think that the brain had its own geometry. How could the external geometry of solids or other figures of our environment be apprehended by neurons if these had no architecture of their own? Astonishing was that the so called ”simple cells”, in the neurons of the primary visual cortex, responded to a bar of light with an axis of orientation that corresponded to the axis of the cell’s receptive field. We tend to consider our brain a reliable organ. But how reliable is it? From the beginning the brain is obliged to transform reality. Brain imagery involves: form, color, motion and sleep. Unintentionally these results led to unexpected philosophical implications. Plato’s pivotal concept that ”forms” exist independently of the material world is reversed. Atoms have been considered to be imaginary for 2,000 years but at present they can be photographed, one by one, with electron microscopes. The reason why geometry has led the way in this inquiry is due to the fact that where there is geometry there is utter simplicity coupled to rigorous order that underlies the phenomenon where it is recognized. Order allows variation but imposes at the same time a canalization that is patent in what we call evolution.
| Author | : Julian Jaynes |
| Publisher | : Houghton Mifflin Harcourt |
| Total Pages | : 580 |
| Release | : 2000-08-15 |
| Genre | : Psychology |
| ISBN | : 0547527543 |
National Book Award Finalist: “This man’s ideas may be the most influential, not to say controversial, of the second half of the twentieth century.”—Columbus Dispatch At the heart of this classic, seminal book is Julian Jaynes's still-controversial thesis that human consciousness did not begin far back in animal evolution but instead is a learned process that came about only three thousand years ago and is still developing. The implications of this revolutionary scientific paradigm extend into virtually every aspect of our psychology, our history and culture, our religion—and indeed our future. “Don’t be put off by the academic title of Julian Jaynes’s The Origin of Consciousness in the Breakdown of the Bicameral Mind. Its prose is always lucid and often lyrical…he unfolds his case with the utmost intellectual rigor.”—The New York Times “When Julian Jaynes . . . speculates that until late in the twentieth millennium BC men had no consciousness but were automatically obeying the voices of the gods, we are astounded but compelled to follow this remarkable thesis.”—John Updike, The New Yorker “He is as startling as Freud was in The Interpretation of Dreams, and Jaynes is equally as adept at forcing a new view of known human behavior.”—American Journal of Psychiatry
| Author | : A. Lima-de-Faria |
| Publisher | : Elsevier Publishing Company |
| Total Pages | : 408 |
| Release | : 1988 |
| Genre | : Science |
| ISBN | : |
The interpretation of evolution is in a state of upheaval: the rapid advancement of Molecular Biology has led into question many of the tenets of Darwinism and neo-Darwinism which, although valuable approaches at the time they were formulated, never fulfilled the criteria demanded by real scientific theories. In this lucidly written new book, now available in paperback, the author presents and discusses the rapid developments in particle physics, crystallography and molecular biology, and formulates a radically different approach to biological evolution. This treatise is not offered as one more new theory but a radically different approach. In the author's opinion, no real theory of evolution can be formulated at present. Selection is not the mechanism of evolution for the simple reason that it cannot be weighed on a balance, poured into a vial, or measured in specific units. Only a material component can be the mechanism of evolution, and this must be searched for in the strict physico-chemical processes.
| Author | : Ben Bova |
| Publisher | : Macmillan |
| Total Pages | : 365 |
| Release | : 2014-04-15 |
| Genre | : Fiction |
| ISBN | : 0765332930 |
"Luke Abramson, a brilliant cellular biologist who is battling lung cancer, has one joy in life, his ten-year-old granddaughter, Angela. When he learns that Angela has an inoperable brain tumor and is given less than six months to live, Abramson wants to try a new enzyme, Mortality Factor 4 (MORF4), that he believes will kill Angela's tumor. However, the hospital bureaucracy won't let him do it because MORF4 has not yet been approved by the FDA. Knowing that Angela will die before he can get approval of the treatment, Abramson abducts Angela from the hospital with plans to take her to a private research laboratory in Oregon. Luke realizes he's too old and decrepit to flee across the country with his sick granddaughter, chased by the FBI. So he injects himself with a genetic factor that will stimulate his body's production of telomerase, an enzyme that has successfully reversed aging in animal tests. As the chase weaves across the country from one research facility to another, Luke begins to grow physically younger, stronger. He looks and feels the way he did thirty or forty years ago. Yet his lung cancer is not abating; if anything the tumors are growing faster. And Angela is dying"--
| Author | : A. Lima-de-Faria |
| Publisher | : JAI Press(NY) |
| Total Pages | : 398 |
| Release | : 1995 |
| Genre | : Science |
| ISBN | : |
Contents. Introduction. Acknowledgments. Part I Periodic Distribution of Properties in Chemical Elements and Minerals. Chapter 1. Periodicity in Chemical Elements. The Order in Chemical ElementsTook Over 100 Years to Establish. The Periodicity of Properties. The Mechanism Underlying the Periodicity in the Chemical Elements. Graphic Display of Chemical Periodicity. Numerous Properties Exhibit Periodic Trends. Anomalies Already Exist at the Level of Chemical Periodicity. Chapter 2. Periodicity in Minerals. Mineral Classification in Based on Chemical Hierarchy. The Periodicity of the Elements Has Determined the Periodicity of Properties in Minerals. Structural and Functional Periodicity-Emergence of the SAme Pattern and Proto-Function in Different Mineral Classes. Part II Periodic Distribution of Functions in Living Organisms. Chapter 3. Period Flight. The Preparation of the Graphs Revealing Biological Periodicity. Flight in Insects Arose from Nowhere. Flight Developed Independently at Five Different Times in Biological Evolution. Flight is Both a Structural and a Functional Process. Flight Demands Many More Structures and Functions than the Existence of a Wing. A Series of Similarities Between the Flight of Insects and that of Birds. Comparison Between the Flight of Bats and Birds. Comparison Between the Flight of Pterosaurs and Birds. The Emergence of Flight in Fish Does Not Appear to be Directly Related to the Environment. Flight in Fish. A Wing and a Fin Can be Made With or Without Bones. The Wing of an Insect and that of a Bird Turn Out to be Built by the Same Genes. Characteristics of Flight Periodicity. Chapter 4. Period Vision. Light-Sensitivity is an Integral Part of the Original Cell Construction. Plant Leaves are Mosaics of Microlenses. Comparison Between the Compound Eyes of Insects and the Light-Sensitive Cells of Leaves. Features of Periodicity in Vision. The Type of Eyes Present from the Protozoa to the Early Chordates. Comparison Between the Eyes of Humans and Cephalopods. Vision Within Insects Displays Periodicity. The Independent Evolution of the Eye Vision and Environment. The Insect Eye and the Human Eye are Produced by the Same Type of Genes. General Features of Vision Periodicity. Chapter 5. Period Placenta. Definition of Placenta. Placenta in Flowering Plants. The Placenta in Invertebrates. The Placenta is Present in Fish. The Placenta in Amphibians and Reptiles. The Placenta Does Not Exist or is Rudimentary in Marsupials. The Periodicity of the Placenta. Chapter 6. Period Bioluminescence. Luminescence in Minerals. Chemical Processes Involved in Bioluminescence. The Occurrence of Bioluminescence. Characteristic Features of Bioluminescence. The Periodicity of Bioluminescence. Chapter 7. Period Penis. The Periodicity of the Occurrence of the Penis Similarities Between the Penis of Humans and Invertebrates. Water Performs with Equal Efficiency the Function of Bones and Other Supporting Tissues. The Emergence of the Penis is Not Directly Related to the General Environment or Organism Complexity. Chapter 8. Period Return to Aquatic Life. Water Changes the Configuration of Minerals and Macromolecules. The Plants that Live in Water have Streamlined Forms. The Plants Reveal that No Change in Genetic Constitution is Necessary to Produce a Novel Hydrodynamic Form and Function. Water-Air and Air-Water Transformations in Plants Experimental Demonstration that Water Decides the Leaf Pattern. The Transformations Involved in the Return to Water in Invertebrates are Similar to Those that Occur Later in Higher Mammals. The Conquest of the Land and the Return to Water in Amphibians. Structural and Functional Modifications in Reptiles Following the Transfer to Aquatic Life. The Hydrodynamic Forms and Functions of Birds Derive from Those of Land Relatives. The Return of Mammals to Aquatic Life Occured Several Times and from Different Orders. The Return of the Carnivores to Water: The Seals. The Sea Cows are Derived from the An
