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Practical Pharmacology for Alzheimer’s Disease

Practical Pharmacology for Alzheimer’s Disease
Author: Takashi Kudo
Publisher: Springer
Total Pages: 144
Release: 2016-02-10
Genre: Medical
ISBN: 3319262068

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In this book, the four leading experts on the ACE inhibitors donepezil, galantamine, and rivastigmine and the NMDA receptor antagonist memantine explain the practical pharmacology of these symptomatic drugs with the aim of providing a sound basis for their clinical use in patients with Alzheimer’s disease. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer’s disease and the book closes with an overview of the ways in which symptomatic drugs for dementia are used. The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer’s disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. The failure of clinical trials of these drugs to yield satisfactory results has, however, meant that for the time being patients continue to be treated only with symptomatic drugs. There is accordingly a need to become more proficient in the use of symptomatic medicines, and it is against the background of this quest that Practical Pharmacology for Alzheimer’s Disease will be of wide interest.


Practical Pharmacology for Alzheimer's Disease

Practical Pharmacology for Alzheimer's Disease
Author: Takashi Kudo
Publisher:
Total Pages:
Release: 2016
Genre: Alzheimer's disease
ISBN: 9783319262055

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The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer's disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. However, the fact that clinical trials of these drugs have not yet yielded satisfactory results has meant that for the time being patients continue to be treated only with symptomatic drugs. Currently, four such drugs are available: donepezil, galantamine, rivastigmine, and memantine. In this book, the four leading experts on each of these drugs explain their practical pharmacology with the aim of providing a sound basis for their use, which to date has been of questionable proficiency. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer's disease and the book closes with an overview of the ways in which symptomatic drugs are used for dementia.


Practical Old Age Psychopharmacology

Practical Old Age Psychopharmacology
Author: Stephen Curran
Publisher: CRC Press
Total Pages: 289
Release: 2018-12-14
Genre: Medical
ISBN: 1498793983

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Tailoring mental illness drug treatments specifically for elderly people has been a neglected area. This book brings together findings from recent multi-disciplinary research and the practical aspects of old age psychiatry. By taking into account the perspectives of the patient and their family, the neuropathologist, the pharmacist, the nurse, the GP, and the specialist, Practical Old Age Psychopharmacology provides a sympathetic analysis of contemporary practice and offers guidelines for the future. Providing the only comprehensive overview of the topic the editors delve into the important role of psychotropic drugs and the management of mental illness in the elderly, how these drugs should be used and how a truly personal approach to patient care can be maintained. To provide a practical focus on specific clinical topics, individual chapters can be used independently This book is an invaluable reference for old age psychiatrists, psychiatrists in training, hospital and community mental health nurses, geriatricians, general practitioners, and pharmaceutical company staff. Clinical psychologists, social workers, occupational therapists and health care managers will also find it beneficial as a complement to their own work.


Practical Old Age Psychopharmacology

Practical Old Age Psychopharmacology
Author: Stephen Curran
Publisher: CRC Press
Total Pages: 289
Release: 2018-12-12
Genre: Medical
ISBN: 1315344289

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Tailoring mental illness drug treatments specifically for elderly people has been a neglected area. This book brings together findings from recent multi-disciplinary research and the practical aspects of old age psychiatry. By taking into account the perspectives of the patient and their family, the neuropathologist, the pharmacist, the nurse, the GP, and the specialist, Practical Old Age Psychopharmacology provides a sympathetic analysis of contemporary practice and offers guidelines for the future. Providing the only comprehensive overview of the topic the editors delve into the important role of psychotropic drugs and the management of mental illness in the elderly, how these drugs should be used and how a truly personal approach to patient care can be maintained. To provide a practical focus on specific clinical topics, individual chapters can be used independently This book is an invaluable reference for old age psychiatrists, psychiatrists in training, hospital and community mental health nurses, geriatricians, general practitioners, and pharmaceutical company staff. Clinical psychologists, social workers, occupational therapists and health care managers will also find it beneficial as a complement to their own work.


Practical Pharmacology in Rehabilitation

Practical Pharmacology in Rehabilitation
Author: Lynette Carl
Publisher: Human Kinetics
Total Pages: 642
Release: 2013-08-19
Genre: Medical
ISBN: 1492581895

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Practical Pharmacology in Rehabilitation: Effect of Medication on Therapy With Web Resource serves as a textbook for students and a reference book for practicing rehabilitation professionals. Rather than discussing pharmacology as it relates to only a limited segment of rehabilitation professions, this text takes an interdisciplinary approach to the effects of medications on rehabilitation patients and assists rehabilitation professionals in designing patient-specific therapy plans based on coexisting disease states. Practical Pharmacology in Rehabilitation explains the necessary pharmacology and then focuses on the relationship between medications and the rehabilitation process. It offers a proactive approach to educating the patient and caregiver, monitoring the patient for side effects, and modifying therapy plans to provide the most effective and safe therapy for each patient. Written by a clinical pharmacist, a speech-language pathologist, and a physical therapist and athletic trainer, this unique guide helps readers in these ways: • Optimize rehabilitation sessions with appropriately timed and dosed administration of medication. • Understand the effects of medication on cognition and learning necessary for accomplishing the tasks of rehabilitation. • Identify medication-associated issues affecting the rehabilitation progress, such as dysphagia and problems with muscle function. • Work with patients, caregivers, staff, and physicians to determine appropriate interventions regarding medication use in patients. In each chapter, Patient Cases based on the authors’ clinical experiences engage readers in understanding how medications can positively or negatively affect the rehabilitation process. Readers will need to consider the role of various medications, drug interactions, and drug intolerances on speech and language, cognition, and ADL and motor functioning as they apply concepts to determine possible solutions to each case. Throughout the text more than 100 easy-to-use tables provide quick access to information, including potential side effects affecting rehabilitation for common medications used in treatment for many conditions and other possible side effects or considerations. Expanded versions of many of these tables are offered as downloadable PDFs in the accompanying web resource. Those tables provide more complete and in-depth coverage by breaking medications down by class, indications, dosage, and potential side effects or interactions. Practical Pharmacology in Rehabilitation begins by presenting foundational concepts necessary for understanding clinical disease states and the impact of medications used for treatment on rehabilitation. Chapters that follow are grouped by categories of clinical disease covering psychiatric and cognitive disorders, neurologic and movement disorders, chronic pain syndromes and substance abuse disorders, immune system disorders, and common chronic diseases such as diabetes, cardiac disease, thyroid and parathyroid disease, respiratory diseases, gastrointestinal diseases, and dysphagia. Each chapter begins with a definition of the condition or special population that it focuses on. Chapters are organized to provide an overview of the pathophysiology, pharmacology, mechanism of action, dosing and monitoring for effects, drug and food interactions, side effects and effects on rehabilitation, and the role of various rehabilitation specialists for each disease state. Summaries conclude each chapter to reinforce the important concepts covered. A glossary is included, and terms are boldfaced in the text to denote their inclusion. A medication index, an index of important terms, and an appendix with information on administering medications using iontophoresis and phonophoresis are also included. With Practical Pharmacology in Rehabilitation, students in rehabilitation and related health care fields can gain essential knowledge to prevent adverse occurrences and medical complications and work with their patients, caregivers, pharmacists, and physicians to optimize rehabilitation and the return to daily living. For rehabilitation professionals, this essential reference provides an integrated understanding of medication use with nonpharmacologic therapies in rehabilitation patients.


Global Clinical Trials for Alzheimer's Disease

Global Clinical Trials for Alzheimer's Disease
Author: Menghis Bairu
Publisher: Academic Press
Total Pages: 428
Release: 2013-08-28
Genre: Medical
ISBN: 0124115306

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Global Clinical Trials for Alzheimer’s Disease is a handy one-stop reference for researchers and physicians planning and conducting global clinical trials in this area. This book addresses important considerations that may arise during the successful design and execution of these trials, including site selection, local regulatory issues, pharmacogenomics, ethical matters and much more. Given the saturation of traditional clinical trial markets and the worldwide progression of Alzheimer’s disease, there is a need to focus on clinical trials in emerging markets and developing countries. This book provides you with a practical approach to recognizing the opportunities and tackling the challenges that are present during the planning and execution of global clinical trials for Alzheimer’s disease. Written by leading experts with hands-on experience in designing and running global Alzheimer’s disease and other neurodegenerative diseases clinical trials A step-by-step guide that provides critical information on the design, conduct and standardization necessary to effectively execute clinical trials and accelerate drug development in this area Includes practical examples, ethical considerations, lessons learned and other valuable tools to aid the planning and implementation of Alzheimer’s disease global clinical trials in emerging markets and developing countries


Pharmacological Treatment of Alzheimer's Disease

Pharmacological Treatment of Alzheimer's Disease
Author: Gustavo Alves Andrade dos Santos
Publisher: Springer Nature
Total Pages: 239
Release: 2022-03-25
Genre: Medical
ISBN: 3030943836

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Alzheimer’s disease is the most prevalent form of dementia. Although it was discovered about a century ago, the first drugs applied in treatment were only introduced in therapy in the last 30 years. This book focuses on the clinical pharmacology of drugs that aim to delay the progression of Alzheimer’s disease, such as anticholinesterases and glutamate receptor antagonists, as well as treatment for the behavioral changes caused by the progression of the disease: antidepressants, antipsychotics, anxiolytics, and mood stabilizers. In addition, it describes important information about the pathophysiology and diagnostic methods of Alzheimer’s disease, emergency situations conditioned by the dementia process, and presents new perspectives for the treatment of Alzheimer’s disease. The ten chapters cover topics such as mechanism of action, dosage regimen, adverse reactions, drug interactions, toxicity profiles, among other information of clinical relevance. The work comprises evidence-based studies, providing a valuable resource for analyzing, prescribing and monitoring patients being treated for Alzheimer’s disease. Written by experts with solid professional experience, this book will appeal to pharmacologists, geriatricians, neurologists, psychiatrists, biomedical clinicians, and other healthcare professionals.


Clinical Psychopharmacology for Neurologists

Clinical Psychopharmacology for Neurologists
Author: George T. Grossberg
Publisher: Springer
Total Pages: 234
Release: 2018-05-15
Genre: Medical
ISBN: 3319746049

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This book provides neurologists with a basic knowledge of psychiatric medications. It begins with general principles of psychopharmacology and the frequency of psychiatric illness in neurology patients. It goes on to cover psychoactive drugs in the elderly and treating behavioral symptoms of dementia. There is a special emphasis on drug-drug and drug-diet interactions that may be seen in clinical practice. Neurologists, residents, neuropsychiatrists, neuropsychologists and psychiatrists in training will find this practical guide invaluable in numerous clinical settings.


Immunotherapy and Biomarkers in Neurodegenerative Disorders

Immunotherapy and Biomarkers in Neurodegenerative Disorders
Author: Martin Ingelsson
Publisher: Methods in Pharmacology and To
Total Pages: 300
Release: 2018-04-28
Genre: Medical
ISBN: 9781493980789

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This practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer's disease, the first sections of the book examine immunotherapeutic approaches for the aforementioned disease as well as for Parkinson's disease and Huntington's disease, amongst others. The last section of the book covers the importance of biomarker techniques to catch these diseases early enough for the treatments to be most useful. Written for the Methods in Pharmacology and Toxicology series, this book contains the kind of detailed descriptions and implementation advice that will offer a smooth transition into the lab. Authoritative and useful, Immunotherapy and Biomarkers in Neurodegenerative Disorders aims to aid in the continued progress in the development of novel immune-based drugs and diagnostic tools for these devastating brain diseases.