Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Plant Glycobiology A Sweet World Of Glycans Glycoproteins Glycolipids And Carbohydrate Binding Proteins PDF full book. Access full book title Plant Glycobiology A Sweet World Of Glycans Glycoproteins Glycolipids And Carbohydrate Binding Proteins.
| Author | : Els J. M. Van Damme |
| Publisher | : Frontiers Media SA |
| Total Pages | : 491 |
| Release | : 2021-10-21 |
| Genre | : Science |
| ISBN | : 2889715213 |
| Author | : Els J. M. Van Damme |
| Publisher | : Frontiers Media SA |
| Total Pages | : 137 |
| Release | : 2015-02-12 |
| Genre | : Botany |
| ISBN | : 2889194213 |
Plants synthesize a wide variety of unique glycan structures which play essential roles during the life cycle of the plant. Being omnipresent throughout the plant kingdom, ranging from simple green algae to modern flowering plants, glycans contribute to many diverse processes. Glycans can function as structural components in the plant cell wall, assist in the folding of nascent proteins, act as signaling molecules in plant defense responses or (ER) stress pathways, or serve within the energy metabolism of a plant. In most cases, glycans are attached to other macromolecules to form so-called glycoconjugates (e.g. glycoproteins, proteoglycans and glycolipids), but they can also be present as free entities residing in the plant cell. Next to the broad, complex set of glycans, plants also evolved an elaborate collection of lectins or proteins with a lectin-like domain, which can recognize and bind to endogenous (plants-own) or exogenous (foreign) glycans. Though still poorly understood in plants, the dynamic interactions between lectins and carbohydrate structures are suggested to be involved in gene transcription, protein folding, protein transport, cell adhesion, signaling as well as defense responses. As such, a complex and largely undetermined glycan-interactome is established inside plant cells, between cells and their surrounding matrix, inside the extracellular matrix, and even between organisms. Studying the biological roles of plant glycans will enable to better understand plant development and physiology in order to fully exploit plants for food, feed and production of pharmaceutical proteins. In this Research Topic, we want to provide a platform for articles describing the latest research, perspectives and methodologies related to the fascinating world of plant glycobiology, with a focus on following subjects: 1. Identification and characterization of plant glycans, their biosynthetic and degradation enzymes 2. Characterization of plant lectins and glycoproteins 3. Plant glycans in the plant’s energy metabolism 4. Role of plant glycans in plant defense signaling 5. Use of plant lectins in pest control 6. Plant lectins as new tools in human medicine 7. Glyco-engineering in plants
| Author | : Ajit Varki |
| Publisher | : CSHL Press |
| Total Pages | : 694 |
| Release | : 1999 |
| Genre | : Medical |
| ISBN | : 9780879696818 |
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
| Author | : Elizabeth Yuriev |
| Publisher | : CRC Press |
| Total Pages | : 351 |
| Release | : 2012-09-27 |
| Genre | : Medical |
| ISBN | : 1439854602 |
Structural Glycobiology covers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the field, and is illustrated throughout by specific examples of how research investigations have yielded key structural and associated biological data on carbohydrates and glycolipids. In particular, the book focuses on: X-ray crystallography and small-angle scattering, NMR, and cryo-electron microscopy techniques Theoretical (modeling-based) approaches, such as molecular mechanics, molecular dynamics, free energy calculations, and carbohydrate docking Alternative techniques for yielding structural information on carbohydrates from complex biological samples Carbohydrates in medicine, specifically in areas that have been directly impacted by our understanding of the structural role of carbohydrates in immune recognition: cancer, organ transplantation, and infection
| Author | : Maureen E. Taylor |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 305 |
| Release | : 2011-04-21 |
| Genre | : Medical |
| ISBN | : 0199569118 |
Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.
| Author | : Minoru Fukuda |
| Publisher | : Elsevier |
| Total Pages | : 422 |
| Release | : 2006-11-14 |
| Genre | : Science |
| ISBN | : 0080468993 |
In the past decade, there has been an explosion of progress in understanding the roles of carbohydrates in biological systems. This explosive progress was made with the efforts in determining the roles of carbohydrates in immunology, neurobiology and many other disciplines, examining each unique system and employing new technology. This volume represents the first of three in the Methods in Enzymology series, including Glycomics (vol. 416) and Functional Glycomics (vol. 417), dedicated to disseminating information on methods in determining the biological roles of carbohydrates. These books are designed to provide an introduction of new methods to a large variety of readers who would like to participate in and contribute to the advancement of glycobiology. The methods covered include structural analysis of carbohydrates, biological and chemical synthesis of carbohydrates, expression and determination of ligands for carbohydrate-binding proteins, gene expression profiling including micro array, and generation of gene knockout mice and their phenotype analyses.
| Author | : Minoru Fukuda |
| Publisher | : IRL Press |
| Total Pages | : 440 |
| Release | : 1993 |
| Genre | : Literary Criticism |
| ISBN | : |
Glycobiology: A Practical Approach describes the essential analytical techniques required to study glycoproteins and will be an important practical guide for all researchers, including those in the pharmaceutical industry, working in this field.
| Author | : Inka Brockhausen |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 388 |
| Release | : 2008-02-04 |
| Genre | : Science |
| ISBN | : 1597451673 |
Glycobiology involves studies of complex carbohydrates and posttrans- tional modifications of proteins, and has become an important interdiscip- nary field encompassing chemistry, biochemistry, biology, physiology, and pathology. Although initial research was directed toward elucidation of the different carbohydrate structures and the enzymes synthesizing them, the field has now moved toward identifying the functions of carbohydrates. The pro- cols described in Glycobiology Protocols form a solid basis for investigations of glycan functions in health and disease. The cloning of many of the genes participating in glycosylation processes has helped to enhance our knowledge of how glycosylation is controlled, but has also added another dimension of complexity to the great heterogeneous variety of the structures of the oligos- charides of glycoproteins, proteoglycans, and glycolipids. A family of similar enzyme proteins exists for each glycosylation step. Glycosyltransferases are extremely specific for both the nucleotide sugar donor and the acceptor s- strate, but many other factors control sugar transfer, including the locali- tion and topology of enzymes, cofactors, possible chaperone proteins, and the availability of sugar acceptor substrates. The analysis of the intracellular organization of glycosylation and of the factors controlling the activities of the participating enzymes in the cell are important areas that need more research efforts. Another challenge for future research is to understand the glycodynamics of a cell, that is, how the cell responds to stimuli leading to biological and pathological changes in terms of alterations in glycosylation, and how this affects the biology of the cell.
| Author | : Hans-Joachim Gabius |
| Publisher | : John Wiley & Sons |
| Total Pages | : 663 |
| Release | : 2008-09-26 |
| Genre | : Science |
| ISBN | : 3527614729 |
A comprehensive survey of the topic, ranging from basic molecular research to clinical applications. Critical reviews by leading experts in each field summarize the state of knowledge and discuss the anticipated benefits of novel approaches and strategies. These include the impact of modern analysis techniques on glycobiology, the use of synthetic neoglycoproteins, or the clinical consequences of new insights into the physiological role of lectins and glycoconjugates in pathology, oncology, immunity, neuroscience and reproduction medicine. Throughout, the aim is to separate realistic applications from mere hopes.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 171 |
| Release | : 2012-10-23 |
| Genre | : Science |
| ISBN | : 0309260868 |
A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.
