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Placebo Effects in Neurologic Disease

Placebo Effects in Neurologic Disease
Author:
Publisher: Academic Press
Total Pages: 280
Release: 2020-06-18
Genre: Medical
ISBN: 0128211199

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Placebo Effects in Neurologic Disease, Volume 153, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Background and Methods in Placebo, Better than Nothing: A Historical Account of Placebos and Placebo Effects from Modern to Contemporary Medicine, Determinants of PE, Strategies for Minimizing PE in Research, Maximizing placebo response in the clinic, Statistical methods for handling PE, Nocebo and Lessebo effects, Ethics of deception, Pain, Parkinson's Disease, Cognitive impairment, Epilepsy, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the International Review of Neurobiology series Updated release includes the latest information on the placebo effect


Placebo Effects

Placebo Effects
Author: Fabrizio Benedetti
Publisher:
Total Pages: 427
Release: 2014
Genre: Medical
ISBN: 0198705085

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One of the most widespread words in medicine is placebo and placebo effect, although it is not always clear what it means exactly. Recent progress in biomedical research has allowed a better clarification of the placebo effect. We know that this is an active psychobiological phenomenon which takes place in the patient's brain and that is capable of influencing both the course of a disease and the response to a therapy. Since publication of the first edition of this book in 2008, there has been an explosion of placebo research, and this new edition brings the topic fully up to date. Throughout, the book emphasizes that there are many placebo effects and critically reviews them in different medical conditions, such as neurological and psychiatric disorders, cardiovascular and respiratory diseases, immune and hormonal responses, as well as oncology, surgery, sports medicine and acupuncture. The psychosocial context around the patient is crucial to the placebo effect, for example the doctor's words and attitudes, and throughout this is considered. Exhaustive in its coverage, and written by a world authority in the field, this is the definitive reference text to the placebo effect - one that is essential for researchers and clinicians across a wide range of medical specialities.


Neurobiology of the Placebo Effect

Neurobiology of the Placebo Effect
Author:
Publisher: Academic Press
Total Pages: 508
Release: 2018-08-23
Genre: Medical
ISBN: 0128154179

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Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics. Presents the latest information on placebo studies in clinically relevant models Provides current research and projects on involved brain circuitry and neurotransmitter systems Contains specific chapters on applications


Placebo Effects

Placebo Effects
Author: Fabrizio Benedetti
Publisher: Oxford University Press, USA
Total Pages: 577
Release: 2021-01-10
Genre: Medical
ISBN: 0198843178

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Placebo Effects (3e) is a significantly updated and expanded new edition of a highly successful and critically acclaimed textbook on placebos. It is the first book to emphasize that there are many placebo effects and reviews them critically in different medical conditions.


Placebos and Nocebos in Headaches

Placebos and Nocebos in Headaches
Author: Dimos D. Mitsikostas
Publisher: Springer
Total Pages: 142
Release: 2019-02-11
Genre: Medical
ISBN: 303002976X

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This book discusses the role of placebos and nocebos in the treatment of headache disorders. These disorders are usually treatable, but safety and tolerability issues mean that available preventive treatments have often limited success, even in the right hands – one in five patients treated with a migraine preventive pharmaceutical agent discontinues treatment for those reasons. The nocebo effect plays a role here, with patients’ negative expectation and previous unpleasant treatment experiences creating negative belief in the treatment’s benefits and safety, which in turn limits treatment outcomes and adherence significantly. In RCTs on migraine prevention, one in 20 patients treated with a placebo discontinued treatment because of adverse events, indicating a considerable nocebo effect; the fewer potential adverse events described in the consent form, the smaller the nocebo effect. As such, physicians treating headache sufferers should acknowledge nocebo as a significant cofactor for treatment adherence and failure, and plan techniques to limit the effects, such as patient education and close follow-up. This highly informative and painstakingly presented book provides scientific insights for professionals and scholars with an interest in internal medicine, neurology and pain medicine.


Functional Movement Disorder

Functional Movement Disorder
Author: Kathrin LaFaver
Publisher: Springer Nature
Total Pages: 455
Release: 2022-02-23
Genre: Medical
ISBN: 3030864952

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This book is a practical manual for clinical practitioners seeking to take an interdisciplinary and multidisciplinary approach to the diagnosis and management of functional movement disorder (FMD). It discusses case vignettes, reviews the diagnostic approach, provides an update on available treatments, highlights clinical pearls and details references for further reading. Organized into three parts, the book begins with a framework for conceptualizing FMD - including its historical context, the biopsychosocial model and an integrated neurologic-psychiatric perspective towards overcoming mind-body dualism. Part II then provides a comprehensive overview of different FMD presentations including tremor, dystonia, gait disorders, and limb weakness, as well as common non-motor issues such as pain and cognitive symptoms. The book concludes with chapters on updated practices in delivering the diagnosis, working with patients and care partners to achieve shared understanding of a complex condition, as well as an overview of evidence-based and evolving treatments. Supplemented with high-quality patient videos, Functional Movement Disorder is written for practicing neurologists, psychiatrists, psychologists, allied mental health professionals, and rehabilitation experts with an interest in learning more about diagnosis and management of FMD.


The Placebo Effect

The Placebo Effect
Author: Anne Harrington
Publisher: Harvard University Press
Total Pages: 276
Release: 1999
Genre: Chemotherapy
ISBN: 9780674669864

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Beginning with a review of the role of placebos in the history of medicine, this book investigates the current surge of interest in placebos, and probes the methodological difficulties of saying scientifically just what placebos can and cannot do.


Clinical Trials in Neurology

Clinical Trials in Neurology
Author: Roberto Guiloff
Publisher: Springer Science & Business Media
Total Pages: 568
Release: 2001-05-05
Genre: Medical
ISBN: 9781852332396

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Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.


You Are the Placebo

You Are the Placebo
Author: Dr. Joe Dispenza
Publisher: Hay House, Inc
Total Pages: 393
Release: 2015-09-08
Genre: Body, Mind & Spirit
ISBN: 1401944590

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Is it possible to heal by thought alone—without drugs or surgery? The truth is that it happens more often than you might expect. In You Are the Placebo, best-selling author, international speaker, chiropractor, and renowned researcher of epigenetics, quantum physics, & neuroscience, Dr. Joe Dispenza shares numerous documented cases of those who reversed cancer, heart disease, depression, crippling arthritis, and even the tremors of Parkinson’s disease by believing in a placebo. Similarly, Dr. Joe tells of how others have gotten sick and even died the victims of a hex or voodoo curse—or after being misdiagnosed with a fatal illness. Belief can be so strong that pharmaceutical companies use double- and triple-blind randomized studies to try to exclude the power of the mind over the body when evaluating new drugs. “In his paradigm-altering book, You Are the Placebo, Dr. Joe Dispenza catapults us beyond thinking of the placebo effect as an anomaly. Through 12 concise chapters that read like a true-life scientific thriller, Dispenza gives us rock-solid reasons to accept the game-changer of our lives: that the placebo effect is actually us, proving to ourselves the greatest possibilities of healing, miracles, and longevity! I love this book and look forward to a world where the secret of the placebo is the foundation of everyday life.” — Gregg Braden, New York Times best-selling author of Deep Truth and The Divine Matrix Chapters Include: Foreward by Dawson Church, Ph.D. Part I. Is It Possible? A Brief History of the Placebo The Placebo Effect in the Brain The Placebo Effect in the Body How Thoughts Change the Brain and the Body Suggestibility Attitudes, Beliefs, and Perceptions The Quantum Mind Three Stories of Personal Transformation Information to Transformation: Proof That You Are the Placebo Part II: Transformation Meditation Preparation Changing Beliefs and Perceptions Meditation Becoming Supernatural Dr. Joe does more than simply explore the history and the physiology of the placebo effect. He asks the question: "Is it possible to teach the principles of the placebo, and without relying on any external substance, produce the same internal changes in a person’s health and ultimately in his or her life?" Then he shares scientific evidence (including color brain scans) of amazing healings from his workshops, in which participants learn his consciousness shifting model of personal transformation, based on practical applications of the so-called placebo effect. The book ends with a "how-to" calming meditation for changing limiting beliefs and mental perceptions that hold us back—the first step in healing. You Are the Placebo combines the latest research in neuroscience, biology, psychology, hypnosis, behavioral conditioning, and quantum physics to demystify the workings of the placebo effect . . . and show how the seemingly impossible can become possible. “I discovered that if I could teach people the scientific model of transformation (bringing in a little quantum physics to help them understand the science of possibility); combine it with the latest information in neuroscience, neuroendocrinology, epigenetics, and psychoneuroimmunology; give them the right kind of instruction; and provide the opportunity to apply that information, then they would experience a transformation... This book is about: empowering you to realize that you have all the biological and neurological machinery to do exactly that. My goal is to demystify these concepts with the new science of the way things really are so that it is within the reach of more people to change their internal states in order to create positive changes in their health and in their external world.” — Dr. Joe Dispenza


Complementary Therapies in Neurology

Complementary Therapies in Neurology
Author: Barry Oken
Publisher: CRC Press
Total Pages: 458
Release: 2003-12-02
Genre: Medical
ISBN: 9781135402495

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Drawing upon the knowledge of expert contributors, Complementary Therapies in Neurology: An Evidence-Based Approach provides an introduction to CAM therapies and how a clinician might use them in the treatment of specific neurologic diseases. Informally divided into two sections, the book explores empirically testable theories about the mechanisms of action involved on CAM modalities. The first section reviews commonly used CAM therapies that have some scientific basis and rationale for their use in neurological disorders including botanicals, manipulative and body-based therapies, mind-body therapies, and alternative medicine systems. The editor has placed discussions of spirituality and placebo effect in separate chapters. His choice of topics is based on the amount of evidence available and how often the therapies are used. The second section supplies an evidence-based overview of the clinical applications of these therapies organized by neurological disease states. Discussing common neurologic problems such as headache, neck and back pain, multiple sclerosis, epilepsy, and dementia, this section follows the structure of conventional neurology textbooks and reviews the relevant evidence in a conventional manner. Written by physicians for physicians, this book is the first choice for information on alternative and complementary therapies in clinical neurology. The book provides current scientifically based evidence on which CAM therapies are useful, which ones may be useful, and which ones are not useful.