Physicochemical Aspects Of Pharmaceutically Relevant Polymers And Nanoparticles In Solution PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Physicochemical Aspects Of Pharmaceutically Relevant Polymers And Nanoparticles In Solution PDF full book. Access full book title Physicochemical Aspects Of Pharmaceutically Relevant Polymers And Nanoparticles In Solution.
| Author | : Gizem Cinar |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2023* |
| Genre | : |
| ISBN | : |
Download Physicochemical Aspects of Pharmaceutically-relevant Polymers and Nanoparticles in Solution Book in PDF, ePub and Kindle
Pharmapolymers, colloids, and self-assembled systems for biomedical purposes have gained significant importance in the last decades. Besides innovative synthesis routes and formulation techniques, the characterization of these multicomponent systems is of great importance to obtain an insight into their physicochemical properties. As presented in this thesis, analytical ultracentrifugation with multi-detection represents a characterization tool with great potential for analyzing macromolecules and polymer-based nanocarriers in solution. Besides analytical ultracentrifugation, asymmetrical flow field-flow fractionation coupled to a multi-angle laser light scattering detector can be utilized to determine essential properties such as particle sizes or molar masses of macromolecules. In this thesis, methods of analytical ultracentrifugation were developed to analyze polymeric nanocarriers. The results were compared to well-established orthogonal techniques such as asymmetrical flow field-flow fractionation coupled to a light scattering detector and standard dynamic light scattering. Thereby, different polymeric multicomponent systems, including nanoparticles, polyplexes, micelles, and bioconjugates were studied. These investigations delivered information such as the colocalization of multiple components, i. e., drug, as well as degradation and drug release studies under various conditions. In particular, studies in human serum and at body temperature are of great importance before in vivo experiments are performed. The presented results will allow to overcome current analytical challenges in the characterization of such multicomponent systems for life science applications and boost the synthetic / formulation improvements due to a deep physicochemical understanding of the systems.
| Author | : Gizem Cinar |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2023* |
| Genre | : |
| ISBN | : |
Download Physicochemical Aspects of Pharmaceutically-relevant Polymers and Nanoparticles in Solution Book in PDF, ePub and Kindle
Pharmapolymers, colloids, and self-assembled systems for biomedical purposes have gained significant importance in the last decades. Besides innovative synthesis routes and formulation techniques, the characterization of these multicomponent systems is of great importance to obtain an insight into their physicochemical properties. As presented in this thesis, analytical ultracentrifugation with multi-detection represents a characterization tool with great potential for analyzing macromolecules and polymer-based nanocarriers in solution. Besides analytical ultracentrifugation, asymmetrical flow field-flow fractionation coupled to a multi-angle laser light scattering detector can be utilized to determine essential properties such as particle sizes or molar masses of macromolecules. In this thesis, methods of analytical ultracentrifugation were developed to analyze polymeric nanocarriers. The results were compared to well-established orthogonal techniques such as asymmetrical flow field-flow fractionation coupled to a light scattering detector and standard dynamic light scattering. Thereby, different polymeric multicomponent systems, including nanoparticles, polyplexes, micelles, and bioconjugates were studied. These investigations delivered information such as the colocalization of multiple components, i. e., drug, as well as degradation and drug release studies under various conditions. In particular, studies in human serum and at body temperature are of great importance before in vivo experiments are performed. The presented results will allow to overcome current analytical challenges in the characterization of such multicomponent systems for life science applications and boost the synthetic / formulation improvements due to a deep physicochemical understanding of the systems.
| Author | : Ligia Gargallo |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 254 |
| Release | : 2009-02-18 |
| Genre | : Science |
| ISBN | : 1402093721 |
Download Physicochemical Behavior and Supramolecular Organization of Polymers Book in PDF, ePub and Kindle
As the title suggests, this monograph features the physicochemical behavior and supramolecular organization of polymers. The book consists of four chapters dealing with solution properties, viscoelastic behavior, physicochemical aspects at interfaces and supramolecular structures of polymeric systems. The classical treatment of the physicochemical behavior of polymers is presented in such a way that the book will meet the requirements of a beginner in the study of polymeric systems in solution and in some aspects of the solid state, as well as those of the experienced researcher in other types of materials. Physicochemical behavior and Supramolecular Organization of Polymers is ultimately, a contribution to the chemistry of materials; it is a powerful reference tool for students and scientists working both in polymer chemistry, polymer physics and materials science.
| Author | : Ijeoma F. Uchegbu |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 602 |
| Release | : 2013-11-23 |
| Genre | : Medical |
| ISBN | : 1461491649 |
Download Fundamentals of Pharmaceutical Nanoscience Book in PDF, ePub and Kindle
Nanoscience or the science of the very small offers the pharmaceutical scientist a wealth of opportunities. By fabricating at the nanoscale, it is possible to exert unprecedented control on drug activity. This textbook will showcase a variety of nanosystems working from their design and construction to their application in the field of drug delivery. The book is intended for graduate students in drug delivery, physical and polymer chemistry, and applied pharmaceutical sciences courses that involve fundamental nanoscience. The purpose of the text is to present physicochemical and biomedical properties of synthetic polymers with an emphasis on their application in polymer therapeutics i.e., pharmaceutical nanosystems, drug delivery and biological performance. There are two main objectives of this text. The first is to provide advanced graduate students with knowledge of the principles of nanosystems and polymer science including synthesis, structure, and characterization of solution and solid state properties. The second is to describe the fundamentals of therapeutic applications of polymers in drug delivery, targeting, response modifiers as well as regulatory issues. The courses, often listed as Advanced Drug Delivery and Applied Pharmaceutics; Polymer Therapeutics; or Nanomedicine, are designed as an overview of the field specifically for graduate students in the Department of Pharmaceutical Sciences Graduate Programs. However, the course content may also be of interest for graduate students in related biomedical research programs. These courses generally include a discussion of the major principles of polymer science and fundamental concepts of application of polymers as modern therapeutics. All courses are moving away from the above mentioned course names and going by ‘pharmaceutical nanoscience or nanosystems’. This area of research and technology development has attracted tremendous attention during the last two decades and it is expected that it will continue to grow in importance. However, the area is just emerging and courses are limited but they are offered.
| Author | : Jie He |
| Publisher | : World Scientific |
| Total Pages | : 675 |
| Release | : 2023-11-03 |
| Genre | : Science |
| ISBN | : 9811259178 |
Download Polymers At Nanoscale (In 2 Volumes) Book in PDF, ePub and Kindle
Making polymers into nanoparticles as an essential step in polymer solution processing is of key importance for many applications of polymers. This book seeks to uncover the basics and recent advances in polymer nanoparticles, including polymer synthesis, self-assembly, properties, and applications. It encompasses the various preparation methods of polymer nanoparticles, broadly ranged from single chain collapse to polymerization methods and solution self-assembly. It showcases a wide range of advanced applications of polymer nanoparticles in several fields that include pharmaceutics (drug and nucleotide delivery), biomedicals (bioimaging, diagnosis, and therapeutics), energy (batteries and solar cells) and environmental (catalysis and water purification).This book is enriched with a comprehensive range of content, incorporating synthesis, properties and applications in polymeric nanoparticles that will serve as a suitable beginner guide and survey book in polymer nanomaterials, as well as a useful tool for graduate students, scientists and practitioners in related fields or industries such as chemistry, materials science and engineering, nanomaterials, energy storage and conversion devices, and biomedicine.
| Author | : Christine Vauthier |
| Publisher | : Springer |
| Total Pages | : 649 |
| Release | : 2017-01-07 |
| Genre | : Medical |
| ISBN | : 3319414216 |
Download Polymer Nanoparticles for Nanomedicines Book in PDF, ePub and Kindle
This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
| Author | : Vijay Kumar Thakur |
| Publisher | : John Wiley & Sons |
| Total Pages | : 610 |
| Release | : 2015-09-22 |
| Genre | : Technology & Engineering |
| ISBN | : 1119041449 |
Download Handbook of Polymers for Pharmaceutical Technologies, Biodegradable Polymers Book in PDF, ePub and Kindle
Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers
| Author | : Vijay Kumar Thakur |
| Publisher | : Springer |
| Total Pages | : 578 |
| Release | : 2015-07-20 |
| Genre | : Technology & Engineering |
| ISBN | : 8132224736 |
Download Eco-friendly Polymer Nanocomposites Book in PDF, ePub and Kindle
This book contains precisely referenced chapters, emphasizing environment-friendly polymer nanocomposites with basic fundamentals, practicality and alternatives to traditional nanocomposites through detailed reviews of different environmental friendly materials procured from different resources, their synthesis and applications using alternative green approaches. The book aims at explaining basics of eco-friendly polymer nanocomposites from different natural resources and their chemistry along with practical applications which present a future direction in the biomedical, pharmaceutical and automotive industry. The book attempts to present emerging economic and environmentally friendly polymer nanocomposites that are free from side effects studied in the traditional nanocomposites. This book is the outcome of contributions by many experts in the field from different disciplines, with various backgrounds and expertises. This book will appeal to researchers as well as students from different disciplines. The content includes industrial applications and will fill the gap between the research works in laboratory to practical applications in related industries.
| Author | : W.C. Forsman |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 312 |
| Release | : 2013-11-11 |
| Genre | : Science |
| ISBN | : 1489904654 |
Download Polymers in Solution Book in PDF, ePub and Kindle
Polymers in Solution was written for scientists and engineers who have serious research interests in newer methods for characterization of polymer solutions, but who are not seasoned experts in the theoretical and experimental aspects of polymer science. In particular, it is assumed that the reader is not familiar with the development of theoretical notions in conformational statistics and the dynamics of chainlike molecules; how these two seemingly diverse theoretical topics are related; and the role played by polymer-solvent interactions. Chapter 1 thus presents background material that introduces most of the essential concepts, including some of the mathematical apparatus most commonly used in these areas of theory. This introduction is followed by five chapters that are more closely related to particular experimental techniques. These chapters introduce further theoretical notions as needed. Three of the chapters present con siderable detail on the experimental methods, while two other chapters deal more with the interpretation of experimental results in terms of current theories. Although neutron scattering has become an almost standard technique for the study of conformational properties of macromolecules in the solid state, there has been less emphasis on its application for characterization of polymer molecules in solution. Chapter 4 covers this growing area of application.
| Author | : Zahid Amjad |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 261 |
| Release | : 2007-05-08 |
| Genre | : Technology & Engineering |
| ISBN | : 0306469154 |
Download Water Soluble Polymers Book in PDF, ePub and Kindle
This volume contains a series of papers originally presented at the symposium on Water Soluble Polymers: Solution Properties and Applications, sponsored by the Division of Colloids and Surface Chemistry of the American Chemical Society. The symposium took place in Las Vegas City, Nevada on 9 to 11th September, 1997 at the 214th American Chemical Society National Meeting. Recognized experts in their - spective fields were invited to speak. There was a strong attendance from academia, g- ernment, and industrial research centers. The purpose of the symposium was to present and discuss recent developments in the solution properties of water soluble polymers and their applications in aqueous systems. Water soluble polymers find applications in a number of fields of which the following may be worth mentioning: cosmetics, detergent, oral care, industrial water treatment, g- thermal, wastewater treatment, water purification and reuse, pulp and paper production, sugar refining, and many more. Moreover, water soluble polymers play vital role in the oil industry, especially in enhanced oil recovery. Water soluble polymers are also used in ag- culture and controlled release pharmaceutical applications. Therefore, a fundamental kno- edge of solution properties of these polymers is essential for most industrial scientists. An understanding of the basic phenomena involved in the application of these polymers, such as adsorption and interaction with different substrates (i. e. , tooth enamel, hair, reverse - mosis membrane, heat exchanger surfaces, etc. ) is of vital importance in developing high performance formulations for achieving optimum efficiency of the system.
