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Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine

Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine
Author: Kristen Reynolds
Publisher: Elsevier Health Sciences
Total Pages: 177
Release: 2016-08-16
Genre: Medical
ISBN: 0323462804

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This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.


Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, An Issue of the Clinics in Laboratory Medicine

Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, An Issue of the Clinics in Laboratory Medicine
Author: Ryan J. Schmidt
Publisher: Elsevier Health Sciences
Total Pages: 129
Release: 2020-06-21
Genre: Medical
ISBN: 0323758460

Download Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, An Issue of the Clinics in Laboratory Medicine Book in PDF, ePub and Kindle

This issue of Clinics in Laboratory Medicine will cover Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies. Curated by Dr. Ryan J. Schmidt, this issue is one of four selected each year by the series Consulting Editor, Milenko Tanasijevic. The volume will include articles on: Features of a Comprehensive Precision Medicine Program for Constitutional Genetic Disorders, Establishing a Precision Medicine Center of Excellence for Rare Disease, High-throughput DNA Sequencing for Rare Disease Diagnosis, Enhancing Diagnosis through RNA Sequencing, Interpretation of Rare Genetic Variants, Clinical Bioinformatics, Precision Therapies for Retinal Dystrophy, Precision Therapies for Muscular Dystrophy, Therapeutic Gene Editing, High Throughput Functional Studies of Genetic Variants, and Patient-specific Disease Models.


Clinical Decision Support for Pharmacogenomic Precision Medicine

Clinical Decision Support for Pharmacogenomic Precision Medicine
Author: Beth Devine
Publisher: Academic Press
Total Pages: 300
Release: 2022-06-14
Genre: Medical
ISBN: 0128244542

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Clinical Decision Support for Pharmacogenomic Precision Medicine: Foundations and Implementation offers overviews, methods and strategies for translating genomic medicine to clinical practice. The book's authors explore incorporating pharmacogenetics into electronic health records, CDS methods and infrastructure for delivery, economic evaluation, the hospital administrations’ role and needs in integration, and patient counseling aspects. The book empowers clinicians, researchers, translational scientists, and data and IT experts to effectively navigate the complex landscape of CDS for pharmacogenomic precision medicine. Illustrative case studies of existing gene networks include CSER, eMERGE, the IGNITE network, DIGITIZE, the CDS Learning Network (RTI), ClinGen, Ubiquitous and CDS Hooks. Offers an applied, case-driven discussion of CDS for pharmacogenomic precision medicine Illustrates key concepts, contemporary developments, and future directions using examples of existing gene networks Features contributions from leading voices in precision medicine and clinical decision support


Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, an Issue of the Clinics in Laboratory Medicine, Volume 40-2

Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, an Issue of the Clinics in Laboratory Medicine, Volume 40-2
Author: Ryan J. Schmidt
Publisher: Elsevier
Total Pages: 240
Release: 2020-06-28
Genre: Medical
ISBN: 9780323758451

Download Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies, an Issue of the Clinics in Laboratory Medicine, Volume 40-2 Book in PDF, ePub and Kindle

This issue of Clinics in Laboratory Medicine will cover Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies. Curated by Dr. Ryan J. Schmidt, this issue is one of four selected each year by the series Consulting Editor, Milenko Tanasijevic. The volume will include articles on: Features of a Comprehensive Precision Medicine Program for Constitutional Genetic Disorders, Establishing a Precision Medicine Center of Excellence for Rare Disease, High-throughput DNA Sequencing for Rare Disease Diagnosis, Enhancing Diagnosis through RNA Sequencing, Interpretation of Rare Genetic Variants, Clinical Bioinformatics, Precision Therapies for Retinal Dystrophy, Precision Therapies for Muscular Dystrophy, Therapeutic Gene Editing, High Throughput Functional Studies of Genetic Variants, and Patient-specific Disease Models.


Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book

Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book
Author: Gregory J. Tsongalis
Publisher: Elsevier Health Sciences
Total Pages: 217
Release: 2022-11-12
Genre: Medical
ISBN: 0443183112

Download Current Topics in Molecular Diagnostics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine, E-Book Book in PDF, ePub and Kindle

In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Current Topics in Molecular Diagnostics and Precision Medicine, an Issue of the Clinics in Laboratory Medicine: Volume 42-4

Current Topics in Molecular Diagnostics and Precision Medicine, an Issue of the Clinics in Laboratory Medicine: Volume 42-4
Author: Gregory J. Tsongalis
Publisher: Elsevier
Total Pages: 0
Release: 2022-11-16
Genre: Medical
ISBN: 9780443183102

Download Current Topics in Molecular Diagnostics and Precision Medicine, an Issue of the Clinics in Laboratory Medicine: Volume 42-4 Book in PDF, ePub and Kindle

In this issue of Clinics in Laboratory Medicine, guest editor Dr. Gregory Tsongalis brings his considerable expertise to Current Topics in Molecular Diagnostics and Precision Medicine. Top experts in the field cover key topics such as syndromic and point-of-care molecular testing; building evidence for clinical use of pharmacogenomics and reimbursement for testing; precision medicine using pharmacogenomic panel-testing; and more. Contains 12 relevant, practice-oriented topics including next-generation sequencing approaches to predicting antimicrobial susceptibility testing results; the role of the human gutome on chronic disease: a review of the microbiome and nutrigenomics; blood group genotyping; review of SARS-CoV-2 antigen and antibody testing in diagnosis and community surveillance; and more. Provides in-depth clinical reviews on current topics in molecular diagnostics and precision medicine, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.


Pharmacogenomic Testing in Current Clinical Practice

Pharmacogenomic Testing in Current Clinical Practice
Author: Alan H. B. Wu
Publisher: Springer Science & Business Media
Total Pages: 276
Release: 2011-02-08
Genre: Medical
ISBN: 1607612836

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While the basic principles of personalized medicine and pharmacogenomics has been covered by numerous texts, there are none to date that focuses on the specific tests themselves that are in current clinical practice and those that are being proposed for implementation in the near future. Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory focuses almost entirely on the specifics of each test that is needed to implement these tests into a clinical laboratory. This volume presents the first compilation of the tests currently in routine clinical use. The chapter authors of this unique and invaluable title comprise a range of renowned authorities and investigators who have conducted the essential clinical trials necessary to justify pharmacogenomic testing today. The book is divided into four parts: Basic Concepts, Specific Pharmacogenomic Targets, Drugs that Cause Delayed Hypersensitivity, and Miscellaneous Drugs. Each author provides a pharmacologic background on the target drug, the need for pharmacogenomic testing, and how results can be translated into clinical decisions. Where appropriate, case studies are given to illustrate typical clinical scenarios. An extensive bibliography is provided so that the reader can refer to the original studies. This well-designed resource will appeal to clinical laboratory directors who are contemplating or assigned the task of establishing a pharmacogenomics laboratory and a wide range of clinicians who must interpret results of testing. Focused and immensely useful, Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory is a timely and outstanding contribution to the literature and will be instrumental in defining this rapidly growing field.


Pharmacogenomics in Precision Medicine

Pharmacogenomics in Precision Medicine
Author: Weimin Cai
Publisher: Springer Nature
Total Pages: 290
Release: 2020-06-12
Genre: Medical
ISBN: 9811538956

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This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.


Pharmacogenomics in Clinical Therapeutics

Pharmacogenomics in Clinical Therapeutics
Author: Loralie J. Langman
Publisher: John Wiley & Sons
Total Pages: 400
Release: 2012-01-09
Genre: Medical
ISBN: 1119959586

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Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring. Pharmacogenomics in Clinical Therapeutics provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug–drug interactions. From a team of expert contributors, Pharmacogenomics in Clinical Therapeutics is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.


Direct to Consumer Testing: The Role of Laboratory Medicine, An Issue of Cardiology Clinics

Direct to Consumer Testing: The Role of Laboratory Medicine, An Issue of Cardiology Clinics
Author: Nicole V Tolan
Publisher: Elsevier Health Sciences
Total Pages:
Release: 2020-02-04
Genre: Medical
ISBN: 0323754457

Download Direct to Consumer Testing: The Role of Laboratory Medicine, An Issue of Cardiology Clinics Book in PDF, ePub and Kindle

This issue of Clinics in Laboratory Medicine, guest edited by Drs. Nicole V. Tolan and Robert Nerenz, will cover Direct to Consumer Testing: The Role of Laboratory Medicine. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: Health Literacy, Identifying Valuable Tests, Challenges with At-Home and Mail-In Direct-to-Consumer Genetic Testing, Self-Ordering and Interpretations, American Association for Clinical Chemistry Direct-to-Consumer Genetic Testing Position Statement, Data Disjunction, Integration of At-Home Testing, Wearable Devices, Oncogene Panels and Risk Calculations, Ethics, and Pharmacy’s Integration and Testing Offered, among others.