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| Author | : N. Anthony Armstrong |
| Publisher | : CRC Press |
| Total Pages | : 294 |
| Release | : 2002-09-11 |
| Genre | : Medical |
| ISBN | : 9780203483091 |
This work provides a description of the principles of experimental design and their application to pharmaceutical research. It includes worked examples taken from a wide variety of pharmaceutical techniques and processes.
| Author | : N. Anthony Armstrong |
| Publisher | : |
| Total Pages | : 274 |
| Release | : 1996 |
| Genre | : |
| ISBN | : 9780130940209 |
| Author | : N. Anthony Armstrong |
| Publisher | : Taylor & Francis Group |
| Total Pages | : 188 |
| Release | : 1990 |
| Genre | : Medical |
| ISBN | : |
Addresses experimental and optimization techniques in the context of pharmaceutical research, formulation and manufacture. Specific techniques are described, showing concepts, benefits and limitations. The book includes clinical and consumer trials from a spectrum of pharmaceutical sciences.
| Author | : Gareth A. Lewis |
| Publisher | : CRC Press |
| Total Pages | : 512 |
| Release | : 1998-09-10 |
| Genre | : Mathematics |
| ISBN | : 0824746880 |
This useful reference describes the statistical planning and design of pharmaceutical experiments, covering all stages in the development process-including preformulation, formulation, process study and optimization, scale-up, and robust process and formulation development.Shows how to overcome pharmaceutical, technological, and economic constraint
| Author | : Sarwar Beg |
| Publisher | : Springer Nature |
| Total Pages | : 99 |
| Release | : 2021-01-12 |
| Genre | : Medical |
| ISBN | : 9813347171 |
This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development. It discusses the applications of experimental designs that shall include oral, topical, transdermal, injectables preparations, and beyond for nanopharmaceutical product development, leading to dedicated case studies on various pharmaceutical experiments through illustrations, art-works, tables and figures. This book is a valuable guide for all academic and industrial researchers, pharmaceutical and biomedical scientists, undergraduate and postgraduate research scholars, pharmacists, biostatisticians, biotechnologists, formulations and process engineers, regulatory affairs and quality assurance personnel.
| Author | : Jelena Djuris |
| Publisher | : Elsevier Inc. Chapters |
| Total Pages | : 31 |
| Release | : 2013-04-10 |
| Genre | : Technology & Engineering |
| ISBN | : 0128091894 |
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett–Burman design, D-optimal designs, response surface methodology, central composite designs, Box–Behnken design, and mixture designs, etc. The reader will be introduced to the experimental domains covered by specific design, making it easier to select the one appropriate for the problem. After theoretical introduction, a number of illustrative examples of design of experiments application in the field of pharmaceutical technology are presented.
| Author | : Walkiria S. Schlindwein |
| Publisher | : John Wiley & Sons |
| Total Pages | : 319 |
| Release | : 2018-01-05 |
| Genre | : Science |
| ISBN | : 1118895215 |
A practical guide to Quality by Design for pharmaceutical product development Pharmaceutical Quality by Design: A Practical Approach outlines a new and proven approach to pharmaceutical product development which is now being rolled out across the pharmaceutical industry internationally. Written by experts in the field, the text explores the QbD approach to product development. This innovative approach is based on the application of product and process understanding underpinned by a systematic methodology which can enable pharmaceutical companies to ensure that quality is built into the product. Familiarity with Quality by Design is essential for scientists working in the pharmaceutical industry. The authors take a practical approach and put the focus on the industrial aspects of the new QbD approach to pharmaceutical product development and manufacturing. The text covers quality risk management tools and analysis, applications of QbD to analytical methods, regulatory aspects, quality systems and knowledge management. In addition, the book explores the development and manufacture of drug substance and product, design of experiments, the role of excipients, multivariate analysis, and include several examples of applications of QbD in actual practice. This important resource: Covers the essential information about Quality by Design (QbD) that is at the heart of modern pharmaceutical development Puts the focus on the industrial aspects of the new QbD approach Includes several illustrative examples of applications of QbD in practice Offers advanced specialist topics that can be systematically applied to industry Pharmaceutical Quality by Design offers a guide to the principles and application of Quality by Design (QbD), the holistic approach to manufacturing that offers a complete understanding of the manufacturing processes involved, in order to yield consistent and high quality products.
| Author | : Sarwar Beg |
| Publisher | : Springer Nature |
| Total Pages | : 190 |
| Release | : 2021-01-22 |
| Genre | : Medical |
| ISBN | : 9813343516 |
This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development. It discusses the applications of experimental designs that shall include oral, topical, transdermal, injectables preparations, and beyond for nanopharmaceutical product development, leading to dedicated case studies on various pharmaceutical experiments through illustrations, art-works, tables and figures. This book is a valuable guide for all academic and industrial researchers, pharmaceutical and biomedical scientists, undergraduate and postgraduate research scholars, pharmacists, biostatisticians, biotechnologists, formulations and process engineers, regulatory affairs and quality assurance personnel.
| Author | : Carrillo-Cedillo, Eugenia Gabriela |
| Publisher | : IGI Global |
| Total Pages | : 429 |
| Release | : 2019-12-13 |
| Genre | : Science |
| ISBN | : 179981520X |
Statistics is a key characteristic that assists a wide variety of professions including business, government, and factual sciences. Companies need data calculation to make informed decisions that help maintain their relevance. Design of experiments (DOE) is a set of active techniques that provides a more efficient approach for industries to test their processes and form effective conclusions. Experimental design can be implemented into multiple professions, and it is a necessity to promote applicable research on this up-and-coming method. Design of Experiments for Chemical, Pharmaceutical, Food, and Industrial Applications is a pivotal reference source that seeks to increase the use of design of experiments to optimize and improve analytical methods and productive processes in order to use less resources and time. While highlighting topics such as multivariate methods, factorial experiments, and pharmaceutical research, this publication is ideally designed for industrial designers, research scientists, chemical engineers, managers, academicians, and students seeking current research on advanced and multivariate statistics.
| Author | : Maria Isabel Rodrigues |
| Publisher | : CRC Press |
| Total Pages | : 324 |
| Release | : 2014-12-11 |
| Genre | : Science |
| ISBN | : 1482299569 |
Experimental Design and Process Optimization delves deep into the design of experiments (DOE). The book includes Central Composite Rotational Design (CCRD), fractional factorial, and Plackett and Burman designs as a means to solve challenges in research and development as well as a tool for the improvement of the processes already implemented. Appr
