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Peptide and Protein Drug Delivery Using Polysaccharides

Peptide and Protein Drug Delivery Using Polysaccharides
Author: Aakanchha Jain
Publisher: Elsevier
Total Pages: 331
Release: 2023-10-10
Genre: Science
ISBN: 0443189269

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Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding. Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran. Adopts an interdisciplinary approach across biochemistry, molecular biology, pharmaceutical sciences and drug delivery, and biotechnological perspectives Features accessible figures, tables and graphical abstracts across all chapters to support understanding Examines various polysaccharides of current interest and aspects affecting their absorption, metabolism, excretion and detection


Peptide and Protein Delivery

Peptide and Protein Delivery
Author: Chris Van Der Walle
Publisher: Academic Press
Total Pages: 381
Release: 2011-05-12
Genre: Science
ISBN: 0123849365

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The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. Discusses the most recent data, ideas and concepts Presents case studies and an industrial perspective Details information from the molecular level to bioprocessing Thought provoking, for the novice to the specialist Timely, for today's biopharmaceuticals market


Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery
Author: Vincent Lee
Publisher: CRC Press
Total Pages: 916
Release: 1990-11-19
Genre: Science
ISBN: 9780824778965

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This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai


Polysaccharides Peptides and Proteins

Polysaccharides Peptides and Proteins
Author: R. T. Coutts
Publisher: Elsevier
Total Pages: 220
Release: 2014-05-12
Genre: Science
ISBN: 1483196127

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Pharmaceutical Monographs, Volume 4: Polysaccharides Peptides and Proteins provides information pertinent to a wide variety of naturally-occurring macromolecules that are either peptide, protein, or polysaccharide in nature, which are important as medicinal and pharmaceutical agents. This monograph presents the basic physical and chemical properties of polysaccharides. Organized into four chapters, this volume begins with an overview of the pharmaceutical importance of the class of compounds known as polysaccharides. This text then provides data on the structure of the polysaccharides that is obtained by isolating and identifying the product formed on hydrolysis of the molecule itself. Other chapters consider plant gums and mucilages as important medicinal and pharmaceutical products. This monograph discusses as well the autohydrolysis of gum arabic. The final chapter deals with the clinical applications of various peptide-type antibiotics. This monograph is a valuable resource for undergraduate students of pharmacy and allied subjects.


Trends and Future Perspectives in Peptide and Protein Drug Delivery

Trends and Future Perspectives in Peptide and Protein Drug Delivery
Author: Vincent Lee
Publisher: CRC Press
Total Pages: 400
Release: 1995-02-01
Genre: Medical
ISBN: 9783718656417

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First published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.


Polysaccharide based Nano-Biocarrier in Drug Delivery

Polysaccharide based Nano-Biocarrier in Drug Delivery
Author: Tapan Kumar Giri
Publisher: CRC Press
Total Pages: 368
Release: 2018-09-03
Genre: Medical
ISBN: 042983067X

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This book discusses various fundamental aspects of polysaccharide based nano-biocarrier drug delivery systems and its application in the delivery of small molecules, proteins, peptides, oligonucleotides and genes. It also discusses advances in drug delivery systems in treatment of cancer, cardiovascular, pulmonary, and infectious diseases.


Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins
Author: Ajay K. Banga
Publisher: CRC Press
Total Pages: 396
Release: 2015-04-23
Genre: Medical
ISBN: 1466566078

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There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The c


Peptide and Protein Drug Delivery

Peptide and Protein Drug Delivery
Author:
Publisher: Munksgaard International Publishers
Total Pages: 492
Release: 1998
Genre: Drug delivery systems
ISBN:

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Therapeutic Peptides and Proteins

Therapeutic Peptides and Proteins
Author: Ajay K. Banga
Publisher: CRC Press
Total Pages: 375
Release: 2005-09-14
Genre: Medical
ISBN: 1420039830

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Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up


Protein and Peptide Drug Delivery

Protein and Peptide Drug Delivery
Author: Nitai Charan Giri
Publisher:
Total Pages: 0
Release: 2020
Genre: Medical
ISBN:

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Protein and peptide-based drugs have great potential applications as therapeutic agents since they have higher efficacy and lower toxicity than chemical drugs. However, difficulty with their delivery has limited their use. In particular, their oral bioavailability is very low, and the transdermal delivery faces absorption limitations. Therefore, most of the protein and peptide-based drugs are administered by the parenteral route. However, this route also has some problems, such as patient discomfort, especially for pediatric use. Extensive research has been performed over the past few decades to develop protein and peptide delivery systems that circumvent the problems mentioned above. Various strategies that have been employed during this time include nanoparticle carriers, absorption enhancers, enzyme inhibitors, mucoadhesive polymers, and chemical modification of protein or peptide structures. However, most of these strategies are focused on the delivery of proteins or peptides via the oral route since it is the most preferred route considering its high level of patient acceptance, long-term compliance, and simplicity. However, other routes of administration such as transdermal, nasal, pulmonary can also be attractive alternatives for protein and peptide delivery. This chapter will discuss the most effective approaches used to develop protein and peptide drug delivery systems.