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Pathogenesis of Idiopathic Scoliosis

Pathogenesis of Idiopathic Scoliosis
Author: Masafumi Machida
Publisher: Springer
Total Pages: 193
Release: 2018-02-23
Genre: Medical
ISBN: 4431565418

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This book provides comprehensive coverage of current topics in idiopathic scoliosis (IS). A three-dimensional deformity of the spine, the condition is characterized by lateral curvature combined with vertebral rotation. The primary lesion, however, lies in the median sagittal plane, taking the form of a lordosis. Although the clinical manifestations of scoliosis have been well documented, its cause and pathogenesis have not yet been determined. Research into what causes IS has focused on the structural elements of the spine, spinal musculature, collagenous structures, the endocrine system, the central nervous system, and genetics. Results of these studies have brought about a new perception of IS epiphenomena, but the main cause of IS remains unknown. Recently, several investigators have produced new hypotheses regarding the cause of IS using the developing techniques of genetics, biochemistry, and neurology. This book is a review of the various causative factors thus far proposed for IS and an introduction to the directions in which research is heading to determine the primary cause of IS.


The Genetics and Development of Scoliosis

The Genetics and Development of Scoliosis
Author: Kenro Kusumi
Publisher: Springer Science & Business Media
Total Pages: 227
Release: 2009-12-15
Genre: Medical
ISBN: 1441914064

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Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.


Adolescent Idiopathic Scoliosis

Adolescent Idiopathic Scoliosis
Author: Peter O. Newton
Publisher: AAOS
Total Pages: 0
Release: 2004
Genre: Scoliosis
ISBN: 9780892033331

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Covers the anatomy, etiology, and natural history of scoliosis - from patient evaluation and an algorithm for treatment to pulmonary function after surgical treatment and the use of instruments to evaluate surgical treatment. This new monograph focuses on the most common form of scoliosis occurring otherwise normal adolescents, affecting spinal alignment, growth, and function.


Idiopathic Scoliosis

Idiopathic Scoliosis
Author: Peter O. Newton
Publisher: Thieme
Total Pages: 945
Release: 2011-01-01
Genre: Medical
ISBN: 1604060255

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Based on over a decade of research and observation conducted by the members of the Harms Study Group and other spinal deformity experts from around the world, this must-have clinical reference provides focused coverage of the most current evaluation and treatment guidelines for idiopathic scoliosis. It draws on case studies to guide readers through specific surgical and nonoperative approaches to the multiple types of adolescent idiopathic spinal deformity, including practical information on the rationale for each approach, techniques, and results. Features: In-depth information culled from vast clinical data of world-renowned experts in the Harms Study Group Curve assessment and treatment recommendations listed by curve type and pattern - Comprehensive discussion of pathogenesis and epidemiology, osteobiologics for spinal fusion, anesthesia for scoliosis surgery, surgical complications, and more Chapters on key treatment decisions, such as the selection of fusion levels, that teach readers how to critically address clinical questions More than 600 high-quality illustrations, including numerous full-color clinical photographs, detailed line drawings, and complementary high-resolution radiographs This state-of-the-art text is ideal for orthopaedic surgeons, neurosurgeons, and spine fellows, and is an invaluable companion for any practitioner involved in the surgical and nonsurgical care of patients with spinal deformity.


Etiology of Adolescent Idiopathic Scoliosis

Etiology of Adolescent Idiopathic Scoliosis
Author:
Publisher:
Total Pages: 18
Release: 2000
Genre: Scoliosis
ISBN: 9781560533337

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This book outlines knowledge and hypotheses of the causation of adolescent idiopathic scoliosis (AIS). It begins with Sevastik and Stokes addressing terminology. It includes the epidemiology and demography of adolescent idiopathic scoliosis, the role of genetic factors, hypothesis of causation, osteopenia, Hueter-Votkmann effect, and the role of the intervertebral disc. It analyzes the structure and composition of the cartilage end plate and intervertebral disc, the significance of the sternum, the thoracospinal concept of etiopathogenesis of adolescent scoliosis, and the skeletal growth.