Pancreatic Cancer Updates In Pathogenesis Diagnosis And Therapies PDF Download
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| Author | : Emad Hamdy Gad |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 130 |
| Release | : 2023-11-02 |
| Genre | : Medical |
| ISBN | : 1803559217 |
Download Pancreatic Cancer - Updates in Pathogenesis, Diagnosis and Therapies Book in PDF, ePub and Kindle
Pancreatic Cancer - Updates in Pathogenesis, Diagnosis and Therapies presents the most recent knowledge on pancreatic cancer, which is a deadly, challenging and catastrophic tumor with a high mortality rate. It is the seventh leading cause of cancer-related mortality worldwide. Pancreatic cancer can be diagnosed clinically, by laboratory measures, by imaging, and by pathological detection. Understanding tumor pathogenesis as well as tumor risk factors is necessary for successful treatment, as is early detection and multidisciplinary treatment. This book provides a comprehensive overview of pancreatic cancer in four sections. Chapters address such topics as prevention, screening, and detection; pathogenesis and risk factors; and pathology and management.
| Author | : Howard Reber |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 553 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461218101 |
Download Pancreatic Cancer Book in PDF, ePub and Kindle
A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease. Among the key topics covered are the prospects for early diagnosis using molecular techniques, the latest diagnostic and therapeutic methods, the role of laparoscopy (diagnostic and therapeutic), and nonsurgical treatment. The reviewers also address the future possibilities for clinical advances, quality of life concerns, and the value of the Japanese "extended Whipple resection." Pancreatic Cancer will become the new standard reference for all clinicians who diagnose and treat this disease, as well as for basic scientists needing a summary of the many recent advances. i
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 392 |
| Release | : 2023-05-31 |
| Genre | : Medical |
| ISBN | : 0443133557 |
Download Pancreatic Cancer: Basic Mechanisms and Therapies Book in PDF, ePub and Kindle
Pancreatic Cancer: Basic Mechanisms and Therapies, Volume 159 in the Advances in Cancer Research, presents the latest release in this ongoing, well-regarded serial with invaluable information on the exciting and fast-moving field of cancer research. Pancreatic cancer (PC) is the third leading cause of cancer-related deaths in the United States. Greater than 90% PCs are Pancreatic ductal adenocarcinomas (PDAC) which have a dismal estimated 5-year overall survival of only 11%. PDAC is predicted to become the second leading cause of mortality in the United States by 2030. In the clinic, the PDAC patients often present with incurable disease at the time of first diagnosis. This cancer is particularly lethal because of its propensity to spread quickly to distant organs including the lymphatic system. PDAC metastasis occurs shortly after tumor initiation and is caused by a complex interaction between autonomous tumor cells and cellular elements of the tumor microenvironment. Although PDAC remains a challenging disease to treat and a leading cause of cancer-related deaths, progress is being made in disease etiology and pathogenesis, and intensive research is focused on developing optimal treatment approaches for patients. Considering the continuous progress being made in understanding PDAC pathogenesis and designing new therapies, it was considered timely to develop an up-to-date thematic issue of Advances in Cancer Research (ACR) focused on PDAC. In this thematic issue, we have included ten review articles by experts that cover cancer disparities, PDAC pathobiology, the roles of the tumor microenvironment, tumor heterogeneity, PC stem cells, genetic and signaling events critical for PDAC pathogenesis, Immunotherapy and chemoresistance in PDAC, and different PDAC mouse models. This special issue highlights recent research progress in PDAC, which bridges the gap between basic and clinical research. The recent overview of Racial Disparities in Pancreatic Cancer Clinical Trials; Overview the evolution of in vivo models for PDAC Up-to-date discussion of diverse genetic and molecular signaling changes in PDAC; Role of tumor heterogeneity in therapy resistance in PDAC; Chemoresistance in PDAC and how to overcome this challenge; Current and emerging approaches and strategies for advancing targeted therapy and immunotherapy for PDAC New insights into the role of epithelial-to-mesenchymal transition, tumor microenvironment (TME) and interactions of TME with cancer stem cells in PDAC pathogenesis, progression and therapeutic resistance
| Author | : Paul G Lankisch |
| Publisher | : |
| Total Pages | : 288 |
| Release | : 1999-03-29 |
| Genre | : |
| ISBN | : 9783642600692 |
Download Pancreatic Disease Book in PDF, ePub and Kindle
| Author | : Ganji Purnachandra Nagaraju |
| Publisher | : Academic Press |
| Total Pages | : 420 |
| Release | : 2020-01-15 |
| Genre | : |
| ISBN | : 9780128194577 |
Download Theranostic Approach for Pancreatic Cancer Book in PDF, ePub and Kindle
Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. This book discusses several topics related to pancreatic cancer such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer Discusses treatment options available currently as well as prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment
| Author | : Andrew W. Bruce |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 363 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1447113985 |
Download Adenocarcinoma of the Prostate Book in PDF, ePub and Kindle
Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.
| Author | : Juan Enrique Dominguez-Munoz |
| Publisher | : John Wiley & Sons |
| Total Pages | : 752 |
| Release | : 2021-03-17 |
| Genre | : Medical |
| ISBN | : 111957014X |
Download Clinical Pancreatology for Practising Gastroenterologists and Surgeons Book in PDF, ePub and Kindle
Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for the development of minimally invasive approaches to pancreatic necrosis. The etiopathogenic knowledge of chronic pancreatitis and other pancreatopaties, like that associated with diabetes mellitus, has developed significantly. Especially important has been the development of the field of cystic pancreatic tumours, which has been reflected in the publication of several guidelines and consensus reports over the last few years. Most research efforts have focused on pancreatic cancer, which have led and will further lead to a significant increase in the therapeutic armamentarium against this devastating disease. Finally, many newly published studies have changed the concept, causes, clinical relevance, diagnosis and treatment of exocrine pancreatic insufficiency. This new edition of Clinical Pancreatology for Practising Gastroenterologists and Surgeons has enjoyed the collaboration of the world’s leading experts in each of the areas of clinical pancreatology with the aim of facilitating gastroenterologists, surgeons, oncologists, internists, nutritionists, diabetologists, paediatricians, radiologists, pathologists and other specialists in their decision making when facing patients with pancreatic diseases in their daily clinical practice. All in all, this book supplies an indispensable update of the relevant aspects of clinical pancreatology.
| Author | : F. T. Bosman |
| Publisher | : International Agency for Research on Cancer |
| Total Pages | : 424 |
| Release | : 2010-10-15 |
| Genre | : Medical |
| ISBN | : |
Download WHO Classification of Tumours of the Digestive System Book in PDF, ePub and Kindle
"The WHO Classification of Tumours of the Digestive System presented in this book reflects the views of a Working Group that convened for an Editorial and Consensus Conference at the International Agency for Research on Cancer (IARC), Lyon, December 10-12, 2009"--P. [5].
| Author | : Douglas B. Evans |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 413 |
| Release | : 2006-04-18 |
| Genre | : Medical |
| ISBN | : 0387216006 |
Download Pancreatic Cancer Book in PDF, ePub and Kindle
The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.
| Author | : Boris Rubinsky |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 320 |
| Release | : 2009-11-25 |
| Genre | : Technology & Engineering |
| ISBN | : 364205420X |
Download Irreversible Electroporation Book in PDF, ePub and Kindle
Non-thermal irreversible electroporation is a new minimally invasive surgical p- cedure with unique molecular selectivity attributes – in fact it may be considered the first clinical molecular surgery procedure. Non-thermal irreversible electro- ration is a molecular selective mode of cell ablation that employs brief electrical fields to produce nanoscale defects in the cell membrane, which can lead to cell death, without an effect on any of the other tissue molecules. The electrical fields can be produced through contact by insertion of electrode needles around the undesirable tissue and non-invasively by electromagnetic induction. This new - dition to the medical armamentarium requires the active involvement and is of interest to clinical physicians, medical researchers, mechanical engineers, che- cal engineers, electrical engineers, instrumentation designers, medical companies and many other fields and disciplines that were never exposed in their training to irreversible electroporation or to a similar concept. This edited book is designed to be a comprehensive introduction to the field of irreversible electroporation to those that were not exposed or trained in the field before and can also serve as a reference manual. Irreversible electroporation is broad and interdisciplinary. Therefore, we have made an attempt to cover every one of the various aspects of the field from an introductory basic level to state of the art.
