Paediatric Drug Optimization For Antibiotics PDF Download
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Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 27 |
Release | : 2023-03-22 |
Genre | : Medical |
ISBN | : 9240068937 |
Download Paediatric drug optimization for antibiotics Book in PDF, ePub and Kindle
Author | : |
Publisher | : World Health Organization |
Total Pages | : 24 |
Release | : 2021-11-19 |
Genre | : Medical |
ISBN | : 924003952X |
Download Paediatric drug optimization standard procedure Book in PDF, ePub and Kindle
The aim of this document is to provide guidance on how to undertake a paediatric drug optimization (PADO) exercise and identify key priority products for research and development. This guidance is for all technical units undertaking a PADO exercise, all stakeholders involved in PADO processes as well as interested organizations and experts involved in the research and development of therapeutics in the public and private sectors.
Author | : John C. Rotschafer |
Publisher | : Humana |
Total Pages | : 0 |
Release | : 2016-03-30 |
Genre | : Medical |
ISBN | : 9781493933211 |
Download Antibiotic Pharmacodynamics Book in PDF, ePub and Kindle
This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these antibiotics might be optimally used in a clinical situation. The book explores pharmacodynamics methods for anti-infective agents, pharmacodynamics of antibacterial agents and non-antibacterial agents, as well as pharmacodynamic considerations and special populations. As part of the Methods in Pharmacology and Toxicology series, chapters include detailed insight and practical information for the lab. Comprehensive and cutting-edge, Antibiotic Pharmacodynamics serves as an ideal reference for scientists investigating advances in antibiotic pharmacodynamics now finding their way into the antibiotic development process used for licensing new antibiotics.
Author | : Wei Zhao |
Publisher | : Frontiers Media SA |
Total Pages | : 160 |
Release | : 2021-10-01 |
Genre | : Science |
ISBN | : 2889714500 |
Download Model-Based Evaluation of Antimicrobial Agents in Children Book in PDF, ePub and Kindle
Topic Editor Johannes N. van den Anker is the Chief Medical Officer at Reveragen Biopharma, as well as holding his positions at academic institutions. The other Topic Editor declares no competing interests with regard to the Research Topic subject.
Author | : Evelyne Jacqz-Aigrain |
Publisher | : CRC Press |
Total Pages | : 830 |
Release | : 2021-02-25 |
Genre | : Medical |
ISBN | : 0849374448 |
Download Paediatric Clinical Pharmacology Book in PDF, ePub and Kindle
The treatment of children with medicinal products is an important scientific area. It is recognized that many medicines that are used extensively in pediatric patients are either unlicensed or off-label. This textbook will help pediatric health professionals effectively treat children with the most appropriate medicine with minimal side effects.
Author | : Mike Sharland |
Publisher | : Oxford University Press, USA |
Total Pages | : 913 |
Release | : 2011-04-07 |
Genre | : Medical |
ISBN | : 0199573581 |
Download Manual of Childhood Infections Book in PDF, ePub and Kindle
This manual gives information on the causative organisms, epidemiology and clinical features of all important childhood infections. It includes guidance on the clinical management of the infections and on steps to be taken to prevent future cases.
Author | : Nunzio Denora |
Publisher | : MDPI |
Total Pages | : 205 |
Release | : 2021-09-02 |
Genre | : Science |
ISBN | : 303650740X |
Download Paediatric Formulation Book in PDF, ePub and Kindle
The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 64 |
Release | : 2008-08-12 |
Genre | : Medical |
ISBN | : 0309178657 |
Download Addressing the Barriers to Pediatric Drug Development Book in PDF, ePub and Kindle
Decades of research have demonstrated that children do not respond to medications in the same way as adults. Differences between children and adults in the overall response to medications are due to profound anatomical, physiological, and developmental differences. Although few would argue that children should receive medications that have not been adequately tested for safety and efficacy, the majority of drugs prescribed for children-50 to 75 percent-have not been tested in pediatric populations. Without adequate data from such testing, prescribing drugs appropriately becomes challenging for clinicians treating children, from infancy through adolescence. Addressing the Barriers to Pediatric Drug Development is the summary of a workshop, held in Washington, D.C. on June 13, 2006, that was organized to identify barriers to the development and testing of drugs for pediatric populations, as well as ways in which the system can be improved to facilitate better treatments for children.
Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 56 |
Release | : 2023-11-21 |
Genre | : Business & Economics |
ISBN | : 9240085173 |
Download Paediatric drug optimization for neglected tropical diseases Book in PDF, ePub and Kindle
Priority-setting is the first step to enable a targeted approach to research and development. Developing a prioritized drug portfolio of the most needed formulations for children is essential to streamline researchers’ and supplier’s efforts and resources around specific dosage forms and formulations that address most urgent needs for children. In general, due to limited financial incentives, few new drugs are being developed for Neglected Tropical Diseases (NTDs). Several NTDs disproportionately affect children compared to adults and, as is the case like for most diseases affecting adults and children, the burden to children is compounded by lack of inclusion of paediatric populations in clinical trials and/or lack of age-appropriate dosing regimens and formulations. The PADO-NTD exercise concluded with a final meeting organized in September 2023 with representatives from the four prioritized disease areas to reach consensus on a final PADO-NTD priority list, watch list and research questions and discuss transversal issues for the way forward. The meeting report will include summaries of the background, discussions and deliberations of all PADO exercises, and final conclusions and outputs of the overall PADO for NTD exercises.
Author | : Matthew Laundy |
Publisher | : Oxford University Press |
Total Pages | : 177 |
Release | : 2016 |
Genre | : Medical |
ISBN | : 0198758790 |
Download Antimicrobial Stewardship Book in PDF, ePub and Kindle
Antibiotic resistance threatens the effective prevention and treatment of infections. Antimicrobial Stewardship provides a practical guide on this growing area, supported by the review of the available evidence, including example case studies.