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| Author | : Aneta Kielar |
| Publisher | : Frontiers Media SA |
| Total Pages | : 140 |
| Release | : 2023-03-20 |
| Genre | : Science |
| ISBN | : 2832517900 |
| Author | : Mahendra K. Thakur |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 300 |
| Release | : 2012-12-11 |
| Genre | : Medical |
| ISBN | : 9400752377 |
This book brings together most up-to-date information on different aspects of brain aging and on the strategies for intervention and therapy of age-related brain disorders. It includes 18 chapters by leading researchers, and each chapter is a comprehensive and critical review of the topic in question, discusses the current scenario and focuses on future perspectives. The target readership is the undergraduate and graduate students in the universities, in medical and nursing colleges, along with the post-graduate researchers and practicing clinicians who would like to know about the latest developments in the field of neurodegenerative disorders and their therapeutic interventions. This book will be of much interest to pharmaceutical, nutrition and healthcare industry for an easy access to accurate and reliable information in the field of aging research and intervention.
| Author | : Abhilash K. Desai |
| Publisher | : Elsevier Health Sciences |
| Total Pages | : 180 |
| Release | : 2010-03-17 |
| Genre | : Medical |
| ISBN | : 1455700320 |
This issue examines what is a healthy aging brain and covers preventive measures for succesful cognitive aging. Topics covered include: A road map to healthy aging brain; Cardiovascular risk factors, cerebrovascular disease burden and healthy aging brain; Healthy aging brain: Impact of head injury, alcohol and environmental toxins; Healthy aging brain: What has sleep go to do with it?; Endocrine aspects of healthy aging brain; Healthy aging brain: Role of exercise and physically active lifestyle; Healthy aging brain: Role of nutrition and nutritional supplements; Healthy aging brain: Role of cognitive reserve, cognitive stimulation and cognitive exercises; Healthy aging brain: Impact of positive and negative emotions; Dementia risk predictor. Are we there yet?; Potential future neuroprotective therapies for neurodegenerative disorders and stroke; Healthy aging brain: Importance of promoting resilience and creativity.
| Author | : Yuichi Takeuchi |
| Publisher | : Frontiers Media SA |
| Total Pages | : 115 |
| Release | : 2023-03-01 |
| Genre | : Science |
| ISBN | : 2832512550 |
Oscillatory brain activities reflect and affect network activities in the brain. They support many physiological functions from motor control to cognition and emotion. Abnormal oscillatory brain activities are commonly observed in neurological and psychiatric disorders including epilepsy, Parkinson’s disease, Alzheimer’s disease, schizophrenia, anxiety/trauma-related disorders, major depressive disorders, addiction, etc. Therefore, these disorders can be considered as common oscillation defects “oscillopathies” despite having distinct behavioral manifestations. Recent advances in brain activity measurements and analyses have allowed us to study the pathological oscillations of each disorder as a possible biomarker of symptoms. Furthermore, novel brain stimulation technologies will enable time- and space-targeted interventions of the pathological oscillations of both neurological and psychiatric disorders as possible therapeutic targets for regulating their symptoms. This Research Topic focused on understanding and controlling pathological oscillations in the brain will provide a comprehensive overview of pathological oscillations in neurological and psychiatric disorders. This Research Topic will also examine correlations or causal relationships between pathological oscillations and the symptoms of disorders with a view to the possible use of oscillations as biomarkers or therapeutic targets. Good animal models that accurately reflect neurological and psychiatric symptoms of patients are necessary for providing the proof-of-concept toward future translational research. Large-scale recording and reliable decoding technologies are crucial for discovering the correlations between pathological oscillations and some symptoms, while time- and space-targeted intervention technologies are necessary for studying their causal relationships, Such data will eventually allow the development of neuroprosthesis devices for pathological oscillations. Revealing the mechanisms of physiological oscillations is also important for the direction of this topic.
| Author | : Bhim M. Adhikari |
| Publisher | : LAP Lambert Academic Publishing |
| Total Pages | : 136 |
| Release | : 2014-12-03 |
| Genre | : |
| ISBN | : 9783659646416 |
Recent experimental studies point to the notion that the brain is a complex dynamical system whose behaviors relating to brain functions and dysfunctions can be described by the physics of network phenomena. The brain consists of anatomical axonal connections among neurons and neuronal populations in various spatial scales. Neuronal interactions and synchrony of neuronal oscillations are central to normal brain functions. Breakdowns in interactions and modifications in synchronization behaviors are usual hallmarks of brain dysfunctions. Here, in this dissertation for PhD degree in physics, we report discoveries of brain oscillatory network activity from two separate studies. These studies investigated the large-scale brain activity during tactile perceptual decision-making and epileptic seizures.
| Author | : |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2017 |
| Genre | : |
| ISBN | : |
Impairment of energy metabolism is a hallmark of brain aging and several neurodegenerative diseases, such as the Alzheimer's disease (AD). Age- and disease-related hypometabolism is commonly associated with oxidative stress and they are both regarded as major contributors to the decline in synaptic plasticity and cognition. Neuroinflammatory changes, entailing microglial activation and elevated expression of inflammatory cytokines, also correlate with age-related cognitive decline. It is still under debate whether the mitochondrial dysfunction-induced metabolic deficits or the microglia activation-mediated neuroinflammation is the initiator of the cognitive changes in aging and AD. Nevertheless, multiple lines of evidence support the notion that mitochondrial dysfunction and chronic inflammation exacerbate each other, and these mechanistic diversities have cellular redox dysregulation as a common denominator. This research topic focuses on the role of a metabolic-inflammatory axis encompassing the bioenergetic activity, brain inflammatory responses and their redox regulation in healthy brain aging and neurodegenerative diseases. Dynamic interactions among these systems are reviewed in terms of their causative or in-tandem occurrence and how the systemic environment, -e.g., insulin resistance, diabetes, and systemic inflammation-, impacts on brain function.
| Author | : Nancy C. Andreasen |
| Publisher | : Harper Collins |
| Total Pages | : 290 |
| Release | : 1985-10-29 |
| Genre | : Health & Fitness |
| ISBN | : 0060912723 |
Details recent advances in neuroscience that have yielded a more accurate understanding of the brain's functions and malfunctions and, in turn, have moved psychiatry away from psychotherapy and into the mainstream biological traditions of medicine.
| Author | : Shozo Tobimatsu |
| Publisher | : Springer |
| Total Pages | : 321 |
| Release | : 2016-02-19 |
| Genre | : Medical |
| ISBN | : 4431557296 |
This book presents an overview of the recent advances in clinical applications of magnetoencephalography (MEG). With the expansion of MEG to neuroscience, its clinical applications have also been actively pursued. Featuring contributions from prominent experts in the fields, the book focuses on the current status of the application of MEG, not only to each nervous system but also to various diseases such as epilepsy, neurological disorders, and psychiatric disorders, while also examining the feasibility of using MEG for these diseases. Clinical Applications of Magnetoencephalography offers an indispensable resource for neurologists, neurosurgeons, pediatricians, and psychiatrists, as well as researchers in the field of neuroscience.
| Author | : Christa Neuper |
| Publisher | : Elsevier |
| Total Pages | : 465 |
| Release | : 2006-12-03 |
| Genre | : Science |
| ISBN | : 0080465595 |
Research on brain oscillations and event-related electroencephalography (EEG) and event-related (de-) synchronization (ERD/ERS) in particular became a rapidly growing field in the last decades. A large number of laboratories worldwide are using ERD/ERS to study cognitive and motor brain function and the importance of this tool in neurocognitive research is widely recognized. This book is a summary of the most current research, methods, and applications of the study of event-related dynamics of brain oscillations. Facing the rapid progress in this field, it brings together, on the one side, fundamental questions of the underlying events, which still remain to be clarified and, on the other side, some of the most significant novel findings, which point to the key topics for future research. In particular, the chapters of this volume cover the neurophysiological fundamentals and models (Section I), new methodological approaches (Section II), current ERD research related to cognitive (Section III) and sensorimotor brain function (Section IV), invasive approaches and clinical applications (Section V), and novel developments of EEG-based brain-computer interfaces and neurofeedback (Section IV).
| Author | : Donald W. Pfaff |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2016-10-27 |
| Genre | : Medical |
| ISBN | : 9781493934737 |
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
