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Organic Nanomaterials for Cancer Phototheranostics

Organic Nanomaterials for Cancer Phototheranostics
Author: Manzar Abbas
Publisher: Elsevier
Total Pages: 274
Release: 2023-09-15
Genre: Technology & Engineering
ISBN: 0323957595

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Organic Nanomaterials for Cancer Phototheranostics highlights the use of biocompatible building blocks to make nanomaterials that can aid in medical treatment through better diagnostic and antitumor efficacy. It synthesizes the current literature on synthetic strategies and designs based on peptides, proteins, polymers, lipids, and their conjugates, as well as composites and complexes with metals and inorganic components used to form the nanomaterials. Mechanistic approaches, clinical problems, and therapeutic and diagnostics mechanisms are covered in each chapter. Cellular interactions and uptake, pharmacokinetics, biodistribution, drug delivery efficiency, and safety concerns of these types of nanomaterials are discussed, as well. Other topics looked at include photostability, clearance, metabolism, in-vitro and in-vivo mechanisms, therapeutic efficacy, imaging, and toxicology. Outlines fabrication and design strategies of peptides, proteins, polymers, lipids, composites, and complexes with metals and inorganic components Discusses the limitations and challenges of organic nanomaterials in clinical use, including their mechanisms of penetration into cancer cells and tissue, photostability, clearance, and metabolism Covers clinical problems and therapeutic and diagnostics mechanisms


Cancer Nanotheranostics

Cancer Nanotheranostics
Author: Muthupandian Saravanan
Publisher: Springer Nature
Total Pages: 379
Release: 2021-10-05
Genre: Medical
ISBN: 3030762637

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Cancer Nanotheranostics, Volume 2 continues the discussion of the important work being done in this field of cancer nanotechnology. The contents of these two volumes are explained in detail as follows. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials, and nano-antibodies. This important second volume discusses nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nanoerythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, safety of nanobiomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics. Volume 2 is a vital continuation of this two-volume set. Together, these two volumes create a comprehensive and unique examination of this important area of research.


Cancer Nanotheranostics

Cancer Nanotheranostics
Author: Muthupandian Saravanan
Publisher: Springer Nature
Total Pages: 362
Release: 2021-10-05
Genre: Medical
ISBN: 3030743306

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Nanotechnology is an interdisciplinary research field that integrates chemistry, engineering, biology, and medicine. Nanomaterials offer tremendous opportunity as well as challenges for researchers. Of course, cancer is one of the world's most common health problems, responsible for many deaths. Exploring efficient anticancer drugs could revolutionize treatment options and help manage cancer mortality. Nanomedicine plays a significant role in developing alternative and more effective treatment strategies for cancer theranostics. This book mainly focuses on the emerging trends using nanomaterials and nanocomposites as alternative anticancer material’s. The book is divided into three main topic areas: how to overcome existing traditional approaches to combat cancer, applying multiple mechanisms to target the cancer cells, and how nanomaterials can be used as effective carriers. The contents highlight recent advances in interdisciplinary research on processing, morphology, structure, and properties of nanostructured materials and their applications to combat cancer.Cancer Nanotheranostics is comprehensive in that it discusses all aspects of cancer nanotechnology. Because of the vast amount of information, it was decided to split this material into two volumes. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy, including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials and nano-antibodies. In the second volume, we discuss the nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nano-erythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, the safety of nano-biomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics.


Bionanotechnology in Cancer

Bionanotechnology in Cancer
Author: D. Sakthi Kumar
Publisher: CRC Press
Total Pages: 679
Release: 2022-10-27
Genre: Medical
ISBN: 0429750412

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The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer, which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews, but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer, focusing on nanodiagnostics and nanotherapy. The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles, magnetic nanoparticles, acoustically reflective nanoparticles, X-ray computed tomography, and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy, magnetic nanoparticles for hyperthermia against cancer, phototherapy, nanotechnology-mediated radiation therapy, nanoparticle-mediated small-RNA deliveries for molecular therapies, and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience, which is considered the last hope for the fight against cancer and will be a highly useful resource for the students, researchers, teachers, and curious readers working in this field or related fields.


Nanomedicine for Cancer Diagnosis and Therapy

Nanomedicine for Cancer Diagnosis and Therapy
Author: Arshi Malik
Publisher: Springer Nature
Total Pages: 249
Release: 2021-08-01
Genre: Medical
ISBN: 9811575649

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This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.


Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy

Emerging Trends in Immunomodulatory Nanomaterials Toward Cancer Therapy
Author: Anubhab Mukherjee
Publisher: Springer Nature
Total Pages: 84
Release: 2022-05-31
Genre: Technology & Engineering
ISBN: 3031016696

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Recently, immunomodulatory nanomaterials have gained immense attention due to their involvement in the modulation of the body’s immune response to cancer therapy. This book highlights various immunomodulatory nanomaterials (including organic, polymer, inorganic, liposomes, viral, and protein nanoparticles) and their role in cancer therapy. Additionally, the mechanism of immunomodulation is reviewed in detail. Finally, the challenges of these therapies and their future outlook are discussed. We believe this book will be helpful to a broad community including students, researchers, educators, and industrialists.


Nanotechnology-Based Precision Tools for the Detection and Treatment of Cancer

Nanotechnology-Based Precision Tools for the Detection and Treatment of Cancer
Author: Chad A. Mirkin
Publisher: Springer
Total Pages: 327
Release: 2015-04-20
Genre: Medical
ISBN: 3319165550

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This book discusses emerging nanotechnology-based tools that have the potential to dramatically impact cancer research, diagnostics, and treatment. Cancer is a complex, devastating, and debilitating disease and, although much progress has been made, novel, more effective diagnostic and treatment options are still needed, especially for advanced cancers. The ultimate goal is to detect cancer early and non-invasively and to provide efficacious and targeted precision treatments that cause fewer harmful side effects. This book explains how nanotechnology can exploit the size-, shape-, and composition-dependent properties of nanomaterials to provide novel tools for precision cancer medicine. It will be of interest to researchers and professionals working in the fields of chemistry, biology, materials science and engineering, and medicine who want to learn more about this fascinating and fast-paced area of research.


Nanooncology

Nanooncology
Author: Gil Gonçalves
Publisher: Springer
Total Pages: 455
Release: 2018-06-01
Genre: Technology & Engineering
ISBN: 3319898787

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This book presents a systematic overview of the most relevant nanomaterials and their respective intrinsic properties that have been highly explored by the scientific community and pharmaceutical companies in several different modalities for cancer therapy and bioimaging. The chapters explore the synergistic effects provided by the different nanostructured materials and highlight the main in vitro and in vivo therapeutic achievements on cancer. This work also provides relevant discussion about the recent progresses and future challenges that nanotechnology faces on the conception of more efficient nanoformulations against primary tumors, circulating cancer cells and metastases.


Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications
Author: Prakash Rai
Publisher: Springer
Total Pages: 484
Release: 2018-11-12
Genre: Technology & Engineering
ISBN: 3030017753

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This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.