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Optical Imaging and Spectroscopy

Optical Imaging and Spectroscopy
Author: David J. Brady
Publisher: John Wiley & Sons
Total Pages: 530
Release: 2009-04-27
Genre: Science
ISBN: 0470443723

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An essential reference for optical sensor system design This is the first text to present an integrated view of the optical and mathematical analysis tools necessary to understand computational optical system design. It presents the foundations of computational optical sensor design with a focus entirely on digital imaging and spectroscopy. It systematically covers: Coded aperture and tomographic imaging Sampling and transformations in optical systems, including wavelets and generalized sampling techniques essential to digital system analysis Geometric, wave, and statistical models of optical fields The basic function of modern optical detectors and focal plane arrays Practical strategies for coherence measurement in imaging system design The sampling theory of digital imaging and spectroscopy for both conventional and emerging compressive and generalized measurement strategies Measurement code design Linear and nonlinear signal estimation The book concludes with a review of numerous design strategies in spectroscopy and imaging and clearly outlines the benefits and limits of each approach, including coded aperture and imaging spectroscopy, resonant and filter-based systems, and integrated design strategies to improve image resolution, depth of field, and field of view. Optical Imaging and Spectroscopy is an indispensable textbook for advanced undergraduate and graduate courses in optical sensor design. In addition to its direct applicability to optical system design, unique perspectives on computational sensor design presented in the text will be of interest for sensor designers in radio and millimeter wave, X-ray, and acoustic systems.


Single-Molecule Optical Detection, Imaging and Spectroscopy

Single-Molecule Optical Detection, Imaging and Spectroscopy
Author: W. E. Moerner
Publisher: John Wiley & Sons
Total Pages: 264
Release: 2008-09-26
Genre: Science
ISBN: 3527614702

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Single Molecule Spectroscopy is one of the hottest topics in today's chemistry. It brings us close to the the most exciting vision generations of chemists have been dreaming of: To observe and examine single molecules! While most of chemistry deals with myriads of molecules, this books presents the latest developments for the detection and investigation of single entities. Written by internationally renowned authors, it is a thorough and comprehensive survey of current methods and their applications.


Photoacoustic Imaging and Spectroscopy

Photoacoustic Imaging and Spectroscopy
Author: Lihong V. Wang
Publisher: CRC Press
Total Pages: 518
Release: 2017-12-19
Genre: Science
ISBN: 1420059920

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Photoacoustics promises to revolutionize medical imaging and may well make as dramatic a contribution to modern medicine as the discovery of the x-ray itself once did. Combining electromagnetic and ultrasonic waves synergistically, photoacoustics can provide deep speckle-free imaging with high electromagnetic contrast at high ultrasonic resolution and without any health risk. While photoacoustic imaging is probably the fastest growing biomedical imaging technology, this book is the first comprehensive volume in this emerging field covering both the physics and the remarkable noninvasive applications that are changing diagnostic medicine. Bringing together the leading pioneers in this field to write about their own work, Photoacoustic Imaging and Spectroscopy is the first to provide a full account of the latest research and developing applications in the area of biomedical photoacoustics. Photoacoustics can provide functional sensing of physiological parameters such as the oxygen saturation of hemoglobin. It can also provide high-contrast functional imaging of angiogenesis and hypermetabolism in tumors in vivo. Discussing these remarkable noninvasive applications and so much more, this reference is essential reading for all researchers in medical imaging and those clinicians working at the cutting-edge of modern biotechnology to develop diagnostic techniques that can save many lives and just as importantly do no harm.


Biomedical Optical Imaging

Biomedical Optical Imaging
Author: James G. Fujimoto
Publisher: Oxford University Press
Total Pages: 435
Release: 2009-04-22
Genre: Science
ISBN: 0199722293

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Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques and applications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technology with exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to the macroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep inside biological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.


Optical Imaging and Microscopy

Optical Imaging and Microscopy
Author: Peter Török
Publisher: Springer
Total Pages: 504
Release: 2007-08-17
Genre: Science
ISBN: 3540695656

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This text on contemporary optical systems is intended for optical researchers and engineers, graduate students and optical microscopists in the biological and biomedical sciences. In three sections, the book discusses high-aperture optical systems, nonlinear optical techniques, and various techniques that are finding new applications. The new second edition has been thoroughly revised and expanded to account for new advances in fluorescence imaging and diffractive optical lenses.


Further Developments in Scientific Optical Imaging

Further Developments in Scientific Optical Imaging
Author: M Bonner Denton
Publisher: Royal Society of Chemistry
Total Pages: 217
Release: 2007-10-31
Genre: Science
ISBN: 1847550959

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The number of researchers using imaging devices in their work continues to increase rapidly. Disciplines including astronomy, biology, chemistry, physics and manufacturers of imaging devices, optical components and complete optical systems are recognising the enormous potential. Further Developments in Scientific Optical Imaging brings together the latest information on commercial and academic research, development and applications in scientific optical imaging, from state-of-the-art devices to exciting explorations in space. Topics range from a new generation of CCDs, through spectroscopic applications of CTDs, to improved image processing and new applications for microscopy and spectroscopy. Experts from around the world provide overviews of important aspects of optical imaging, such as design considerations, device fabrication and integration, and data reduction. Comprehensive and international in coverage, this book will be welcomed by developers, manufacturers and users of this technology in universities, observatories and businesses around the world.


In Vivo Optical Imaging of Brain Function

In Vivo Optical Imaging of Brain Function
Author: Ron D. Frostig
Publisher: CRC Press
Total Pages: 494
Release: 2009-05-06
Genre: Science
ISBN: 142007685X

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These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques a


New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging

New Horizons in Time-Domain Diffuse Optical Spectroscopy and Imaging
Author: Yoko Hoshi
Publisher: MDPI
Total Pages: 246
Release: 2020-06-23
Genre: Science
ISBN: 3039361007

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Jöbsis was the first to describe the in vivo application of near-infrared spectroscopy (NIRS), also called diffuse optical spectroscopy (DOS). NIRS was originally designed for the clinical monitoring of tissue oxygenation, and today it has also become a useful tool for neuroimaging studies (functional near-infrared spectroscopy, fNIRS). However, difficulties in the selective and quantitative measurements of tissue hemoglobin (Hb), which have been central in the NIRS field for over 40 years, remain to be solved. To overcome these problems, time-domain (TD) and frequency-domain (FD) measurements have been tried. Presently, a wide range of NIRS instruments are available, including commonly available commercial instruments for continuous wave (CW) measurements, based on the modified Beer–Lambert law (steady-state domain measurements). Among these measurements, the TD measurement is the most promising approach, although compared with CW and FD measurements, TD measurements are less common, due to the need for large and expensive instruments with poor temporal resolution and limited dynamic range. However, thanks to technological developments, TD measurements are increasingly being used in research, and also in various clinical settings. This Special Issue highlights issues at the cutting edge of TD DOS and diffuse optical tomography (DOT). It covers all aspects related to TD measurements, including advances in hardware, methodology, the theory of light propagation, and clinical applications.


Mathematics and Physics of Emerging Biomedical Imaging

Mathematics and Physics of Emerging Biomedical Imaging
Author: Committee on the Mathematics and Physics of Emerging Dynamic Biomedical Imaging
Publisher: National Academies Press
Total Pages: 261
Release: 1996-03-13
Genre: Science
ISBN: 0309552923

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This cross-disciplinary book documents the key research challenges in the mathematical sciences and physics that could enable the economical development of novel biomedical imaging devices. It is hoped that the infusion of new insights from mathematical scientists and physicists will accelerate progress in imaging. Incorporating input from dozens of biomedical researchers who described what they perceived as key open problems of imaging that are amenable to attack by mathematical scientists and physicists, this book introduces the frontiers of biomedical imaging, especially the imaging of dynamic physiological functions, to the educated nonspecialist. Ten imaging modalities are covered, from the well-established (e.g., CAT scanning, MRI) to the more speculative (e.g., electrical and magnetic source imaging). For each modality, mathematics and physics research challenges are identified and a short list of suggested reading offered. Two additional chapters offer visions of the next generation of surgical and interventional techniques and of image processing. A final chapter provides an overview of mathematical issues that cut across the various modalities.


Principles of Nonlinear Optical Spectroscopy

Principles of Nonlinear Optical Spectroscopy
Author: Shaul Mukamel
Publisher: Oxford University Press on Demand
Total Pages: 543
Release: 1999
Genre: Science
ISBN: 9780195132915

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This textbook presents a systematic and unifying viewpoint for a wide class of nonlinear spectroscopic techniques in time domain and frequency domain. It is directed towards active researchers in physics, optics, chemistry, and materials science, as well as graduate students who enter this complex and rapidly developing field. Nonlinear optical interactions of laser fields with matter provide powerful spectroscopic tools for the understanding of microscopic interactions and dynamic processes. One of the major obstacles facing researchers in this field, however, is the flood of experimental techniques and terminologies, which create a serious language barrier. The general microscopic correlation function approach to the nonlinear optical response developed in this book is essential for understanding the relationships among different techniques and a comparison of their information content, the design of new measurements, and for a systematic comparison of the optical response of different systems such as dyes in solutions, atoms and molecules in the gas phase, liquids, molecular aggregates and superlatives, and semiconductor nanostructures. The approach is based on formulating the nonlinear response by representing the state of matter by the density matrix and following its evolution on Liouville space. Current active research areas such as femtosecond time-domain techniques, semi-classical and wave-packet dynamics, pulse shaping, pulse locking, exciton confinement, and the interplay of electronic, nuclear and field coherence are emphasized. The material has been developed from the author's highly successful interdisciplinary course at the University of Rochester attended by science and engineering graduate students.