Opportunities And Approaches For Supplying Molybdenum 99 And Associated Medical Isotopes To Global Markets PDF Download
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| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 87 |
| Release | : 2018-02-12 |
| Genre | : Medical |
| ISBN | : 030946630X |
Download Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets Book in PDF, ePub and Kindle
Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 264 |
| Release | : 2016-11-28 |
| Genre | : Medical |
| ISBN | : 0309445310 |
Download Molybdenum-99 for Medical Imaging Book in PDF, ePub and Kindle
The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 220 |
| Release | : 2009-06-27 |
| Genre | : Medical |
| ISBN | : 0309130395 |
Download Medical Isotope Production Without Highly Enriched Uranium Book in PDF, ePub and Kindle
This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.
| Author | : Aurobindo Sarkar |
| Publisher | : Packt Publishing |
| Total Pages | : 412 |
| Release | : 2018-02-01 |
| Genre | : Computers |
| ISBN | : 9781787289314 |
Download Learning AWS Book in PDF, ePub and Kindle
Discover techniques and tools for building serverless applications with AWS Key Features Get well-versed with building and deploying serverless APIs with microservices Learn to build distributed applications and microservices with AWS Step Functions A step-by-step guide that will get you up and running with building and managing applications on the AWS platform Book Description Amazon Web Services (AWS) is the most popular and widely-used cloud platform. Administering and deploying application on AWS makes the applications resilient and robust. The main focus of the book is to cover the basic concepts of cloud-based development followed by running solutions in AWS Cloud, which will help the solutions run at scale. This book not only guides you through the trade-offs and ideas behind efficient cloud applications, but is a comprehensive guide to getting the most out of AWS. In the first section, you will begin by looking at the key concepts of AWS, setting up your AWS account, and operating it. This guide also covers cloud service models, which will help you build highly scalable and secure applications on the AWS platform. We will then dive deep into concepts of cloud computing with S3 storage, RDS and EC2. Next, this book will walk you through VPC, building realtime serverless environments, and deploying serverless APIs with microservices. Finally, this book will teach you to monitor your applications, and automate your infrastructure and deploy with CloudFormation. By the end of this book, you will be well-versed with the various services that AWS provides and will be able to leverage AWS infrastructure to accelerate the development process. What you will learn Set up your AWS account and get started with the basic concepts of AWS Learn about AWS terminology and identity access management Acquaint yourself with important elements of the cloud with features such as computing, ELB, and VPC Back up your database and ensure high availability by having an understanding of database-related services in the AWS cloud Integrate AWS services with your application to meet and exceed non-functional requirements Create and automate infrastructure to design cost-effective, highly available applications Who this book is for If you are an I.T. professional or a system architect who wants to improve infrastructure using AWS, then this book is for you. It is also for programmers who are new to AWS and want to build highly efficient, scalable applications.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 173 |
| Release | : 2007-09-11 |
| Genre | : Medical |
| ISBN | : 0309134153 |
Download Advancing Nuclear Medicine Through Innovation Book in PDF, ePub and Kindle
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
| Author | : |
| Publisher | : |
| Total Pages | : 122 |
| Release | : 2019 |
| Genre | : |
| ISBN | : 9789264625099 |
Download The Supply of Medical Isotopes Book in PDF, ePub and Kindle
This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 144 |
| Release | : 1995-01-27 |
| Genre | : Medical |
| ISBN | : 0309176697 |
Download Isotopes for Medicine and the Life Sciences Book in PDF, ePub and Kindle
Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 87 |
| Release | : 2018-03-12 |
| Genre | : Medical |
| ISBN | : 030946627X |
Download Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets Book in PDF, ePub and Kindle
Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.
| Author | : Philip Ball |
| Publisher | : Oxford University Press |
| Total Pages | : 193 |
| Release | : 2004-04-08 |
| Genre | : Science |
| ISBN | : 0192840991 |
Download The Elements: A Very Short Introduction Book in PDF, ePub and Kindle
This Very Short Introduction traces the history and cultural impact of the elements on humankind, and examines why people have long sought to identify the substances around them. Looking beyond the Periodic Table, the author takes the reader on an engaging and entertaining tour: from the Greek philosophers who propounded a system with four elements - earth, air, fire, and water - to the modern-day scientists who are able to create their own.
| Author | : International Atomic Energy Agency |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2017 |
| Genre | : Technology & Engineering |
| ISBN | : 9789201029164 |
Download Cyclotron Based Production of Technetium-99m Book in PDF, ePub and Kindle
This publication presents a comprehensive overview of the technologies involved in the production of cyclotron based 99mTc. These would include techniques relevant to preparation of targets, irradiation of targets under high beam currents, target processing, target recovery and quality control of the final product. The publication provides broad information, well supported with references, on improved production routes and improved separation and purification of cyclotron based 99mTc. These approaches achieve high specific activity and chemical purity of 99mTc suitable for labelling molecules of medical interest and also enable spare capacity to be available at medical cyclotron centres. The readership of this publication is scientists interested in translating this technology to practice, technologists already working with cyclotrons wanting to enhance the utility of the existing machines and managers who are in the process of setting up facilities in their countries. Students working towards higher level degrees in related fields may also benefit from this publication.
