Oncogenes And Growth Factors PDF Download
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Author | : Patricia Kahn |
Publisher | : Springer Science & Business Media |
Total Pages | : 384 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642733255 |
Download Oncogenes and Growth Control Book in PDF, ePub and Kindle
How is growth controlled in normal cells? How are the growth control mechanisms perturbed in cancer cells? This book provides an up-to-date description of research aimed at resolving these questions. It is organized into four sections, each containing a series of short reviews written by experts in the field. The general headings are: growth factors, receptors, and related oncogenes: transduction of mitogenic signals and ras oncogenes; nuclear oncogenes and regulation of gene expression; and multiple steps involved in malignant transformation. The articles emphasize concepts rather than detailed facts and are intended not only for specialists in the field but also for interested readers, such as physicians and advanced students, who wish to stay abreast of developments in one of the most exciting fields in current biomedical research.
Author | : Robert C. Bast, Jr. |
Publisher | : John Wiley & Sons |
Total Pages | : 2004 |
Release | : 2017-03-10 |
Genre | : Medical |
ISBN | : 111900084X |
Download Holland-Frei Cancer Medicine Book in PDF, ePub and Kindle
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author | : Gordon Guroff |
Publisher | : Wiley-Interscience |
Total Pages | : 410 |
Release | : 1987 |
Genre | : Genes |
ISBN | : |
Download Oncogenes, Genes, and Growth Factors Book in PDF, ePub and Kindle
Touching on virtually every area of biological science, from neurobiology to oncology and from basic research to clinical protocols, the chapters in this contributed work address every known structural relationship between growth factor, or growth factor receptor, and oncogene. The seminal observations published three years ago by Doolittle et al and Waterfield et al that there is a close structural relationship between the platelet-derived growth factor and the V-sis oncogene electrified the field. And aside from their structural relationship, it is now clear that many of the growth factors, acting on their target cells, induce the transcription of a battery of oncogenes. This volume represents the first effort to collect such material in one place. Chapters cover in detail the background information available about the factors for which relationships have been established. Other chapters offer detailed discussions of growth factor receptor genes for which relationships have not yet been observed. The information gathered here should prove invaluable to researchers in this new and rapidly advancing field.
Author | : Enrique Pimentel |
Publisher | : CRC Press |
Total Pages | : 274 |
Release | : 1987-06-30 |
Genre | : Medical |
ISBN | : 9780849353468 |
Download Hormones Growth Factors & Oncogenes Book in PDF, ePub and Kindle
This text examines the hormones and peptide growth factors involved in the regulation of metabolism, growth and differentiation in metazoan organisms and proto-oncogene expression. Investigates protein products of some proto-oncogenes for involvement in the transductional and post-transductional and mechanisms of hormones and peptide growth factors.
Author | : Ralph A. Bradshaw |
Publisher | : Elsevier Science & Technology |
Total Pages | : 342 |
Release | : 1987 |
Genre | : Medical |
ISBN | : |
Download Oncogenes and Growth Factors Book in PDF, ePub and Kindle
Author | : M. Bolla |
Publisher | : Inserm |
Total Pages | : 244 |
Release | : 1989 |
Genre | : Medical |
ISBN | : |
Download Growth Factors and Oncogenes Book in PDF, ePub and Kindle
Author | : Mels Sluyser |
Publisher | : John Wiley & Sons |
Total Pages | : 218 |
Release | : 1987 |
Genre | : Breast |
ISBN | : |
Download Growth Factors and Oncogenes in Breast Cancer Book in PDF, ePub and Kindle
Author | : David A. Frank |
Publisher | : Springer Science & Business Media |
Total Pages | : 358 |
Release | : 2002-12-31 |
Genre | : Medical |
ISBN | : 1402073402 |
Download Signal Transduction in Cancer Book in PDF, ePub and Kindle
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Author | : J. E. Kudlow |
Publisher | : Springer Science & Business Media |
Total Pages | : 237 |
Release | : 2013-11-09 |
Genre | : Science |
ISBN | : 1475719809 |
Download Biology of Growth Factors Book in PDF, ePub and Kindle
Growth factors are elaborated to control the growth of cells in such physiological processes as wound healing, tissue regeneration and the immune response. Abnormal production of these growth factors, their receptors or intracellular med!ators of their action may lead to disease states including oncogenesis. This volume will focus on exciting developments in defining the precise molecular lesions that permit the conversion of controlled proliferative signals to neoplasia, on the possible involvement of growth factors in the development of blood vessel diseases as seen in diabetes and atherosclerosis, on the altered immune surveillance that leads to autoimmunity and on the fundamental mechanisms by which growth factors signal their target cells. We expect that the contents of this volume will help promote understanding of the role of these fundamental biological processes and their alterations in a wide variety of disease states and stimulate new investi gations in this important area of biomedical research. The Editors v CONTENTS PERSPECTIVES ON THE CONTROL OF GROWTH AND DIFFERENTIATION Perspectives on the Biology of Growth Factors . . . •. . . . . . . . . . . . . . . • I. B. Fritz Platelet-Derived Growth Factor- Its Role in Health and Disease. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 R. Ross and E. W. Raines Molecular and Developmental Biology Aspects of Fibroblast Growth Factor. • . . . . . . . . . . . . . . • . . . . . . . . . • • . . . . . . . . . . . . . . . . . . • 23 D. Gospodarowicz Chemical and Biochemical Properties of Human Angiogenin. . . . . . . . . . 41 B. L. Vallee and J. F. Riordan GROWTH FACTOR - ONCOGENE RELATIONSHIPS Structure - Function Relationships in Cellular and Viral fps/fes Cytoplasmic Protein-Tyrosine Kinases. . . . . . . . . . . . . . . . . . . . . . . . 55 T. Pawson. P. Greer, M. Moran, K.
Author | : S. Papa |
Publisher | : Birkhäuser |
Total Pages | : 315 |
Release | : 2013-03-11 |
Genre | : Medical |
ISBN | : 303488950X |
Download Cell Growth and Oncogenesis Book in PDF, ePub and Kindle
Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. This book comprises recent results on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolism pathways during oncogenesis.