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| Author | : Pythagoras Cutchis |
| Publisher | : |
| Total Pages | : 180 |
| Release | : 1978 |
| Genre | : Skin |
| ISBN | : |
| Author | : Pythagoras Cutchis |
| Publisher | : |
| Total Pages | : 164 |
| Release | : 1978 |
| Genre | : Radiation carcinogenesis |
| ISBN | : |
The linkage of solar ultraviolet radiation to skin cancer is investigated in this paper by making comparisons of incidence rates in countries with predominantly white populations with respect to geographic, time, age, and anatomic site variations. It is concluded that the evidence in support of the hypothesis that solar ultraviolet radiation is a dominant factor in the induction of squamous cell and basal cell carcinomas is convincing. Many anomalies of various kinds are found in the hypothesis that solar ultraviolet radiation is a significant factor in the induction of malignant melanoma, leading to the conclusion that the primary cause(s) for this class of tumors must be sought elsewhere. Analysis of the data indicates that urbanization is an important factor in the etiology of basal cell carcinoma and, to a lesser degree, in the etiology of malignant melanoma. The biological amplification factor (ratio of percent increase in non-melanoma skin cancer incidence to percent increase in ultraviolet dose) is estimated to lie between 1 and 2. (Author).
| Author | : Pythagoras Cutchis |
| Publisher | : |
| Total Pages | : 173 |
| Release | : 1978 |
| Genre | : Skin |
| ISBN | : |
| Author | : |
| Publisher | : |
| Total Pages | : 146 |
| Release | : 1978 |
| Genre | : |
| ISBN | : |
| Author | : Jörg Reichrath |
| Publisher | : Springer Nature |
| Total Pages | : 428 |
| Release | : 2020-09-11 |
| Genre | : Medical |
| ISBN | : 3030462277 |
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
| Author | : David Hill |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 332 |
| Release | : 2013-03-14 |
| Genre | : Medical |
| ISBN | : 9401705119 |
Our series Cancer Prevention - Cancer Control continues to address the causes and prevention of cancer. In this volume, Hill, Elwood, and English bring together a rich resource summarizing the state of science underpinning the primary prevention of skin cancer. While skin cancer causes an increasing burden, particularly in populations of European origin, our understanding of the role of sun exposure together with the genetic components of skin cancer continues to grow. Given the emphasis on evidence-based medicine and public health prevention efforts, it is noteworthy that, although we can all access the same evidence base, countries around the world have had remarkably different responses to the application of this knowledge to prevent skin cancer. The outstanding contribution of the Australian public health community to the scientific understanding of skin cancer etiology and the translation of this knowledge into national prevention efforts uniquely positions the editors to compile this volume focused on the primary prevention of skin cancer. In so doing they draw on an international team of authors to present a “state of the science” summary of skin cancer prevention and to identify those areas where uncertainty remains. To achieve successful prevention of cancer we must translate our scientific knowledge base into effective prevention programs. This book offers the reader keen insights into the depth of our understanding of etiologic pathways for skin cancer. This etiologic science base is complemented by rigorous prevention science placing emphasis on the social context for effective and sustained prevention efforts.
| Author | : IARC Working Group on Risk of Skin Cancer and Exposure to Artificial Ultraviolet Light |
| Publisher | : World Health Organization |
| Total Pages | : 84 |
| Release | : 2006 |
| Genre | : Medical |
| ISBN | : |
This report represents the views and expert opinions of an IARC Working Group that met in Lyon, France, 27-29 June 2005
| Author | : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans |
| Publisher | : IARC |
| Total Pages | : 540 |
| Release | : 2004 |
| Genre | : Medical |
| ISBN | : 9789283212843 |
A working group of 23 experts from 13 countries met in Lyon to evaluate the evidence for carcinogenicity of arsenic (mostly naturally occurring) as a contaminant of drinking-water, and of the water-disinfectant chloramine. The working group also evaluated or re-evaluated four chlorination by-products found in drinking-water, namely chloral hydrate, di- and trichloroacetic acids, and 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (also known as MX). High-level exposure to arsenic in drinking-water occurs in some regions such as China, Latin America, Bangladesh and West Bengal. The Working Group reviewed epidemiological studies of human cancer (mainly ecological studies in Taiwan and Chile, and several case-control and cohort studies) in relation to arsenic in drinking-water. Arsenic in drinking-water (primarily inorganic, as arsenate and to a lesser extent arsenite) was evaluated as carcinogenic to humans (Group 1) on the basis of sufficient evidence for an increased risk for cancer of the urinary bladder, lung and skin. Studies on inorganic arsenic in experimental animals provided limited evidence for its carcinogenicity, but sufficient evidence was found in experimental animals for the carcinogenicity of dimethylarsinic acid (an organic form of arsenic), which produced urinary bladder tumours in rats and lung tumours in mice after oral administration.
| Author | : Peter Altmeyer |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 1476 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 3642607713 |
UV radiation is recognized as the major risk factor for skin can cer. For the last three decades the incidence and mortality of skin cancer have been increasing steadily in almost all parts of the world. Unfortunately, there have been very few advances in the management and treatment of skin cancer. In comparison to other malignant tumors, skin cancer offers the unique opportuni ty to identify this tumor at an early stage. Thus, there is strong interest in preventing death by early diagnosis and prompt treat ment. The proceedings of the International Congress on Skin Cancer and UV Radiation which was held in Bochum Germany in October 1996, reflect the newest scientific standards in the field of skin cancer. The conference in Bochum was a platform for leading scientists from all over the world to discuss the complexity and diversity of UV radiation in its interaction with the skin. Starting with basic science like physiology, immunology, and molecular biochemistry of the skin as influenced by UV radiati on, the book presents a profound survey into the field of skin can cer by focusing on the latest scientific results in prevention, early detection, treatment, and epidemiology. The congress in Bochum in 1996 was organized to provide a starting point for coordinated European strategies against skin cancer with internationally renown scientists.
| Author | : Christa Baumstark-Khan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 560 |
| Release | : 1999-03-31 |
| Genre | : Technology & Engineering |
| ISBN | : 9780792356677 |
Human health as well as aquatic and terrestrial ecosystems are threatened from increa sing levels of environmental radiation of various sources, many of them of anthropoge nic causality: large areas of the former Soviet Union suffer from radioactive pollution, in particular after the Chemobyl accident; the increase in the incidence of UVB radiati on at the Earth's surface as a result of a progressive depletion of stratospheric ozone is a global problem that requires international concerted actions; in areas of former uranium mining the natural radiation level is substantially increased due to elevated radon levels; a growing portion of the population involved in air traffic is exposed to increased levels of natural radiation; and with the International Space Station an increasing number of astronauts will be exposed to the complex field of cosmic radiation. To estimate the corresponding risks, a better knowledge of the underlying radiobiological mechanisms at the molecular, cellular and system level is required. This book is the result of a multidisciplinary effort to discuss the current state of knowledge of the fundamental processes that result from interactions of environmental radiation -ionizing as well as UV radiation -with living matter and the existing radiati on protection concepts, and then to define future research work needed as fundamental information for the assessment of risks from increased levels of environmental radiation to human health and ecosystem balance. It comprises the key lectures and statements presented at the NATO Advanced Research Workshop.
