Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 452 Chronic Toxicity Studies PDF Download

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies
Author: OECD
Publisher: OECD Publishing
Total Pages: 18
Release: 2018-06-27
Genre:
ISBN: 9264071202

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies Book in PDF, ePub and Kindle

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies
Author: OECD
Publisher: OECD Publishing
Total Pages: 20
Release: 2018-06-27
Genre:
ISBN: 9264071229

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 453: Combined Chronic Toxicity/Carcinogenicity Studies Book in PDF, ePub and Kindle

The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents
Author: OECD
Publisher: OECD Publishing
Total Pages: 16
Release: 2018-06-27
Genre:
ISBN: 9264070702

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents Book in PDF, ePub and Kindle

This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been obtained from acute or repeated dose ...


OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology

OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology
Author: OECD
Publisher: OECD Publishing
Total Pages: 12
Release: 2006-09-11
Genre:
ISBN: 9264035443

Download OECD Guidelines for the Testing of Chemicals / Section 4: Health Effects Summary of Considerations in the Report from the OECD Expert Groups on Short Term and Long Term Toxicology Book in PDF, ePub and Kindle


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents
Author: OECD
Publisher: OECD Publishing
Total Pages: 9
Release: 1998-09-21
Genre:
ISBN: 9264070729

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents Book in PDF, ePub and Kindle

This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents
Author: OECD
Publisher: OECD Publishing
Total Pages: 13
Release: 2008-10-16
Genre:
ISBN: 9264070680

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents Book in PDF, ePub and Kindle

This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The method is based on the repeated oral administration of the substance of interest during one limited period (one dose level ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity
Author: OECD
Publisher: OECD Publishing
Total Pages: 13
Release: 2017-10-09
Genre:
ISBN: 9264070583

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity Book in PDF, ePub and Kindle

This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study
Author: OECD
Publisher: OECD Publishing
Total Pages: 14
Release: 2018-06-27
Genre:
ISBN: 9264070826

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study Book in PDF, ePub and Kindle

This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure
Author: OECD
Publisher: OECD Publishing
Total Pages: 14
Release: 2002-02-08
Genre:
ISBN: 926407094X

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure Book in PDF, ePub and Kindle

A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...