Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 441 Hershberger Bioassay In Rats A Short Term Screening Assay For Antiandrogenic Properties PDF Download
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| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 20 |
| Release | : 2009-09-08 |
| Genre | : |
| ISBN | : 9264076336 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 441: Hershberger Bioassay in Rats A Short-term Screening Assay for (Anti)Androgenic Properties Book in PDF, ePub and Kindle
The Hershberger Bioassay is an in vivo short–term screening test. It evaluates the ability of a chemical to elicit biological activities consistent with androgen agonists, antagonists or 5 á-reductase inhibitors. The current bioassay is based on the ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 21 |
| Release | : 2007-10-15 |
| Genre | : |
| ISBN | : 9264067418 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 440: Uterotrophic Bioassay in Rodents A short-term screening test for oestrogenic properties Book in PDF, ePub and Kindle
The Uterotrophic Bioassay is an in vivo short-term screening test. It is based on the increase in uterine weight or uterotrophic response. The Uterotrophic Bioassay relies for its sensitivity on an animal test system in which the ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 27 |
| Release | : 2011-07-28 |
| Genre | : |
| ISBN | : 9264122648 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 456: H295R Steroidogenesis Assay Book in PDF, ePub and Kindle
This Test Guideline describes an in vitro screen for chemical effects on steroidogenesis, specifically the production of 17ß-estradiol (E2) and testosterone (T). The human H295R adreno-carcinoma cell line, used for the assay, expresses genes that ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 9 |
| Release | : 1998-09-21 |
| Genre | : |
| ISBN | : 9264070729 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 409: Repeated Dose 90-Day Oral Toxicity Study in Non-Rodents Book in PDF, ePub and Kindle
This method provides information on health hazard likely to arise from short-term exposure to test substance. The determination of sub-chronic oral toxicity using repeated doses may be carried out after initial information on toxicity has been ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 25 |
| Release | : 2018-06-27 |
| Genre | : |
| ISBN | : 9264185372 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 443: Extended One-Generation Reproductive Toxicity Study Book in PDF, ePub and Kindle
This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 14 |
| Release | : 2002-02-08 |
| Genre | : |
| ISBN | : 926407094X |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure Book in PDF, ePub and Kindle
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 15 |
| Release | : 1997-07-21 |
| Genre | : |
| ISBN | : 9264071024 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 424: Neurotoxicity Study in Rodents Book in PDF, ePub and Kindle
This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 6 |
| Release | : 1986-10-23 |
| Genre | : |
| ISBN | : 9264071504 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 485: Genetic toxicology, Mouse Heritable Translocation Assay Book in PDF, ePub and Kindle
The mouse heritable translocation test detects structural and numerical chromosome changes in mammalian germ cells as recovered in first generation progeny. The types of chromosome changes detected in this test system are reciprocal translocations ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 16 |
| Release | : 2016-07-29 |
| Genre | : |
| ISBN | : 9264264388 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 421: Reproduction/Developmental Toxicity Screening Test Book in PDF, ePub and Kindle
This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 38 |
| Release | : 2009-09-08 |
| Genre | : |
| ISBN | : 9264076220 |
Download OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 230: 21-day Fish Assay A Short-Term Screening for Oestrogenic and Androgenic Activity, and Aromatase Inhibition Book in PDF, ePub and Kindle
This Test Guideline describes an in vivo screening assay for certain endocrine active substances where sexually mature male and spawning female fish are held together and exposed to a chemical during a limited part of their life-cycle (21 days ...
