Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 414 Prenatal Developmental Toxicity Study PDF Download

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study
Author: OECD
Publisher: OECD Publishing
Total Pages: 14
Release: 2018-06-27
Genre:
ISBN: 9264070826

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 414: Prenatal Developmental Toxicity Study Book in PDF, ePub and Kindle

This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...


Test No. 443: Extended One-Generation Reproductive Toxicity Study

Test No. 443: Extended One-Generation Reproductive Toxicity Study
Author: OECD
Publisher: OECD Publishing
Total Pages: 25
Release: 2011-07-28
Genre:
ISBN: 9264122559

Download Test No. 443: Extended One-Generation Reproductive Toxicity Study Book in PDF, ePub and Kindle

This Test Guideline is designed to provide an evaluation of reproductive and developmental effects that may occur as a result of pre- and postnatal chemical exposure as well as an evaluation of systemic toxicity in pregnant and lactating females and ...


Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test

Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test
Author: OECD
Publisher: OECD Publishing
Total Pages: 14
Release: 1996-03-22
Genre:
ISBN: 9264070982

Download Test No. 422: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test Book in PDF, ePub and Kindle

The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks; females should be dosed throughout the study (approximately 54 days). Normally, matings “one male to one ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study
Author: OECD
Publisher: OECD Publishing
Total Pages: 8
Release: 1983-05-26
Genre:
ISBN: 9264070842

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 415: One-Generation Reproduction Toxicity Study Book in PDF, ePub and Kindle

This Test Guideline for reproduction testing is designed to provide general information concerning the effects of a test substance (Solid, liquid, gas or vapour) on male and female reproductive performance. The test substance is administered orally ...


Test No. 421: Reproduction/Developmental Toxicity Screening Test

Test No. 421: Reproduction/Developmental Toxicity Screening Test
Author: OECD
Publisher: OECD Publishing
Total Pages: 10
Release: 1995-07-27
Genre:
ISBN: 9264070966

Download Test No. 421: Reproduction/Developmental Toxicity Screening Test Book in PDF, ePub and Kindle

The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity
Author: OECD
Publisher: OECD Publishing
Total Pages: 13
Release: 2001-01-22
Genre:
ISBN: 9264070869

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 416: Two-Generation Reproduction Toxicity Book in PDF, ePub and Kindle

This Test Guideline for two-generation reproduction testing is designed to provide general information concerning the effects of a test substance on the integrity and performance of the male and female reproductive systems, and on the growth and ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study
Author: OECD
Publisher: OECD Publishing
Total Pages: 26
Release: 2007-10-15
Genre:
ISBN: 9264067396

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 426: Developmental Neurotoxicity Study Book in PDF, ePub and Kindle

A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies
Author: OECD
Publisher: OECD Publishing
Total Pages: 18
Release: 2018-06-27
Genre:
ISBN: 9264071202

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies Book in PDF, ePub and Kindle

The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity
Author: OECD
Publisher: OECD Publishing
Total Pages: 13
Release: 2017-10-09
Genre:
ISBN: 9264070583

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 402: Acute Dermal Toxicity Book in PDF, ePub and Kindle

This method provides information on health hazard likely to arise from a short-term exposure to solid or liquid test substance by the dermal route. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea pig may be ...


OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure
Author: OECD
Publisher: OECD Publishing
Total Pages: 14
Release: 2002-02-08
Genre:
ISBN: 926407094X

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure Book in PDF, ePub and Kindle

A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...