Oecd Guidelines For The Testing Of Chemicals Section 2 Test No 251 Rapid Androgen Disruption Activity Reporter Radar Assay PDF Download
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| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 44 |
| Release | : 2022-06-30 |
| Genre | : |
| ISBN | : 9264910557 |
Download OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 251: Rapid Androgen Disruption Activity Reporter (RADAR) assay Book in PDF, ePub and Kindle
The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect chemicals active on the androgen axis.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 84 |
| Release | : 2023-07-04 |
| Genre | : |
| ISBN | : 9264264361 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 458: Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals Book in PDF, ePub and Kindle
This Test Guideline describes in vitro assays, which use Androgen Receptor TransActivation (ARTA) to detect Androgen Receptor Agonists and Antagonists. The ARTA assay methods are mechanistically and functionally similar test methods that provide information on the transcription and translation of a reporter gene following the binding of a chemical to the androgen receptor and subsequent transactivation.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 45 |
| Release | : 2021-06-17 |
| Genre | : |
| ISBN | : 9264886109 |
Download OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 250: EASZY assay - Detection of Endocrine Active Substances, acting through estrogen receptors, using transgenic tg(cyp19a1b:GFP) Zebrafish embrYos Book in PDF, ePub and Kindle
The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b promoter. The EASZY assay allows for the detection of estrogenic activity of chemicals on transgenic tg(cyp19a1b:GFP) Zebrafish embryos exposed for 96 hours during the embryonic stages of development.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 74 |
| Release | : 2021-06-17 |
| Genre | : |
| ISBN | : 9264265295 |
Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 455: Performance-Based Test Guideline for Stably Transfected Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists and Antagonists Book in PDF, ePub and Kindle
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology of Stably Transfected Transactivation to detect Estrogen Receptor Agonists and Antagonists (ER TA assays).
| Author | : Beate Escher |
| Publisher | : IWA Publishing |
| Total Pages | : 273 |
| Release | : 2011-12-15 |
| Genre | : Science |
| ISBN | : 1843393689 |
Download Bioanalytical Tools in Water Quality Assessment Book in PDF, ePub and Kindle
Part of Water Quality Set - Buy all four books and save over 30% on buying separately! Bioanalytical Tools in Water Quality Assessment reviews the application of bioanalytical tools to the assessment of water quality including surveillance monitoring. The types of water included range from wastewater to drinking water, including recycled water, as well as treatment processes and advanced water treatment. Bioanalytical Tools in Water Quality Assessment not only demonstrates applications but also fills in the background knowledge in toxicology/ecotoxicology needed to appreciate these applications. Each chapter summarises fundamental material in a targeted way so that information can be applied to better understand the use of bioanalytical tools in water quality assessment. Bioanalytical tools in Water Quality Assessment can be used by lecturers teaching academic and professional courses and also by risk assessors, regulators, experts, consultants, researchers and managers working in the water sector. It can also be a reference manual for environmental engineers, analytical chemists, and toxicologists. Authors: Beate Escher, National Research Centre for Environmental Toxicology (EnTox), The University of Queensland, Australia, Frederic Leusch, Smart Water Research Facility (G51), Griffith University Gold Coast Campus, Australia. With contributions by Heather Chapman and Anita Poulsen
| Author | : Arnold Lyle Aspelin |
| Publisher | : |
| Total Pages | : 44 |
| Release | : 1997 |
| Genre | : Pesticides |
| ISBN | : |
Download Pesticides Industry Sales and Usage Book in PDF, ePub and Kindle
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 31 |
| Release | : 2016-07-29 |
| Genre | : |
| ISBN | : 9264264337 |
Download OECD Guidelines for the Testing of Chemicals, Section 2 Test No. 243: Lymnaea stagnalis Reproduction Test Book in PDF, ePub and Kindle
This Test Guideline is designed to assess effects of prolonged exposure to chemicals on the reproduction and survival of the hermaphrodite freshwater snail Lymnaea stagnalis (the Great Pond Snail).
| Author | : Damia Barcelo |
| Publisher | : Elsevier |
| Total Pages | : 349 |
| Release | : 2006-09-29 |
| Genre | : Science |
| ISBN | : 0080466672 |
Download Sediment Quality and Impact Assessment of Pollutants Book in PDF, ePub and Kindle
Volume 1 of the Sustainable Management of Sediment Resources mini-series is the first attempt to fill many of these gaps in knowledge and also in practice. The volume includes sections on: Sampling Characterization of contaminants in sediments being bioavailability the main issue Chemical analysis Biological analysis Effect directed analysis and toxicity Identification evaluation Benthos sediment quality assessment Modelling of pollutant fate and behaviour Sediment quality guidelines This first volume is applicable to a wide audience, from students at the graduate level, to experienced researchers and laboratory personnel in academia, industry and government. This volume also available as part of a 4-volume set, ISBN 0444519599. Discount price for set purchase. A broad overview on sediment quality and impact assessment of pollutants Suitable for both newcomers to the field of sediment treatment and specialists alike Outlines practical examples of methods used in sediment quality analysis
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 423 |
| Release | : 2017-08-14 |
| Genre | : Science |
| ISBN | : 0309458625 |
Download Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals Book in PDF, ePub and Kindle
To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.
| Author | : Nathan Burroughs |
| Publisher | : Springer |
| Total Pages | : 222 |
| Release | : 2019-05-23 |
| Genre | : Education |
| ISBN | : 303016151X |
Download Teaching for Excellence and Equity Book in PDF, ePub and Kindle
This open access book examines the interrelationship of national policy, teacher effectiveness, and student outcomes with a specific emphasis on educational equity. Using data from the IEA’s Trends in International Mathematics and Science Study (TIMSS) conducted between 1995 and 2015, it investigates grade four and grade eight data to assess trends in key teacher characteristics (experience, education, preparedness, and professional development) and teacher behaviors (instructional time and instructional content), and how these relate to student outcomes. Taking advantage of national curriculum data collected by TIMSS to assess changes in curricular strategy across countries and how these may be related to changes in teacher and student factors, the study focuses on the distributional impact of curriculum and instruction on students, paying particular attention to overall inequalities and variations in socioeconomic status at the student and country level, and how such factors have altered over time. Multiple methods, including regression and fixed effects analyses, and structural equation modelling, establish the evolution of these associations over time.
